Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Juan José Nogal"'
Publikováno v:
Pathogens, Vol 13, Iss 2, p 126 (2024)
More than one million curable sexually transmitted infections occur every day. Trichomonas vaginalis is one of the main infections responsible for these epidemiological data; however, the diagnosis of this protozoan is still mainly based on microscop
Externí odkaz:
https://doaj.org/article/337b0fe715f841a6b80913b2937fa3b0
Autor:
Alexandra Ibáñez Escribano, Alfredo Meneses Marcel, Yanetsy Machado Tugores, Juan José Nogal Ruiz, Vicente J Arán Redó, José Antonio Escario García-Trevijano, Alicia Gómez Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss 5, Pp 637-643 (2012)
A fluorimetric microassay that uses a redox dye to determine the viability of the flagellate Trichomonas vaginalis has been optimised to provide a more sensitive method to evaluate potential trichomonacidal compounds. Resazurin has been used in recen
Externí odkaz:
https://doaj.org/article/3d54a80d7ae7461d8654683bf4d01c96
Autor:
Susana Muelas-Serrano, Ana Le-Senne, Carlos Fernández-Portillo, Juan José Nogal, Carmen Ochoa, Alicia Gómez-Barrio
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 97, Iss 4, Pp 553-557 (2002)
Nitroarylidenemalononitriles and their cyanoacetamide derivatives with remarkable anti-epimastigote properties, were synthesized attempting to obtain new 3,5-diamino-4-(5'-nitroarylidene)-4H-thiadiazine 1,1-dioxide derivatives, which in previous repo
Externí odkaz:
https://doaj.org/article/0ae5da67da4f43f78c11c8f57d93e43b
Autor:
Alexandra Ibáñez-Escribano, Leyre Pernaute Lau, Juan José Nogal-Ruiz, Alicia Gómez-Barrio, Jose Antonio Escario, Michael A. Zeligs
Publikováno v:
Proceedings, Vol 1, Iss 6, p 645 (2017)
New, safe, well tolerated, and versatile anti-trichomonal agents for oral and topical use are needed to combat spreading resistance of Trichomonas vaginalis to metronidazole (MTZ). [...]
Externí odkaz:
https://doaj.org/article/5fa70984e779414299cc7d67a749b245
Autor:
Alexandra Ibáñez-Escribano, Nerea Vela, Felipe Reviriego, Cristina Fonseca-Berzal, Vicente J. Arán, Juan José Nogal-Ruiz, Alicia Gómez-Barrio, José Antonio Escario
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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E-Prints Complutense. Archivo Institucional de la UCM
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E-Prints Complutense. Archivo Institucional de la UCM
A series of 11 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles (2–12) has been prepared starting from 1-benzyl-5-nitroindazol-3-ol 13, and evaluated against sensitive and resistant isolates of the sexually transmitted protozoan Trichomonas vaginalis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3001b7853b50b016b3da7f2e64b24d
https://eprints.ucm.es/id/eprint/70434/
https://eprints.ucm.es/id/eprint/70434/
Autor:
José Cumella, Juan José Nogal-Ruiz, Alexandra Ibáñez-Escribano, Vicente J. Arán, Felipe Reviriego, Nadine Jagerovic, Cristina Fonseca-Berzal, Patrícia Bernardino da Silva, Maria de Nazaré Correia Soeiro, Alicia Gómez-Barrio, José Antonio Escario, Paula Morales
Publikováno v:
European Journal of Medicinal Chemistry. 115:295-310
Two series of new 5-nitroindazole derivatives, 1-substituted 2-benzylindazolin-3-ones ( 6 – 29 , series A ) and 3-alkoxy-2-benzyl-2 H -indazoles ( 30 – 37 , series B ), containing differently functionalized chains at position 1 and 3, respectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5b614271c074e66364500dee955667
https://doi.org/10.1016/j.ejmech.2016.03.036
https://doi.org/10.1016/j.ejmech.2016.03.036
Autor:
Alexandra Ibáñez-Escribano, César R. García-Jacas, Yanetsy Machado-Tugores, Alfredo Meneses-Marcel, Juan José Nogal-Ruiz, Vicente J Arán-Redó, Stephen J. Barigye, Enrique Teran, Yovani Marrero-Ponce, Alicia Gómez-Barrio, José Antonio Escario
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Aim: Metronidazole is the most widely used drug in trichomoniasis therapy. However, the emergence of metronidazole-resistant Trichomonas vaginalis isolates calls for the search for new drugs to counter the pathogenicity of these parasites. Results: C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da738f327f15ba2a1180d7cb73e46074
https://pubmed.ncbi.nlm.nih.gov/29589477
https://pubmed.ncbi.nlm.nih.gov/29589477
Autor:
Vicente J. Arán, Alexandra Ibáñez-Escribano, Alicia Gómez-Barrio, José Antonio Escario, Patrícia Bernardino da Silva, Marcos Meuser Batista, Alfredo Meneses-Marcel, Juan José Nogal-Ruiz, Maria de Nazaré Correia Soeiro, José Cumella, Cristina Fonseca-Berzal, Nerea Vela, Sergio Sifontes-Rodríguez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Three different series of new 5-nitroindazole derivatives—1-(ω-aminoalkyl)-2-benzylindazolin-3-ones (series A; ten compounds), 3-(ω-aminoalkoxy)-2-benzylindazoles (series B; four compounds) and 3-alkylamino-2-benzylindazoles (series C; five compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b138a72a34ab6fa3a9879b631a01b5e
https://pubmed.ncbi.nlm.nih.gov/29624912
https://pubmed.ncbi.nlm.nih.gov/29624912
Autor:
Alicia Gómez-Barrio, Alexandra Ibáñez-Escribano, Jorge Pérez-Serrano, Juan José Nogal-Ruiz, J. Antonio Escario, John F. Alderete
Publikováno v:
Acta Tropica. 149:1-7
Trichomonas vaginalis is known to evade complement-mediated lysis. Because the genome of T. vaginalis does not possess DNA sequence with homology to human protectin (CD59), a complement lysis restricting factor, we tested the hypothesis that host CD5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e13dd41d97ce7980414132fb7b0fd7
https://doi.org/10.1016/j.actatropica.2015.05.003
https://doi.org/10.1016/j.actatropica.2015.05.003
Autor:
José Antonio Escario, Alicia Gómez-Barrio, Juan José Nogal-Ruiz, Leyre Pernaute Lau, Alexandra Ibáñez-Escribano, Michael A. Zeligs
Publikováno v:
E-Prints Complutense. Archivo Institucional de la UCM
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Proceedings, Vol 1, Iss 6, p 645 (2017)
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Proceedings, Vol 1, Iss 6, p 645 (2017)
New, safe, well tolerated, and versatile anti-trichomonal agents for oral and topical use are needed to combat spreading resistance of Trichomonas vaginalis to metronidazole (MTZ). Diindolylmethane (DIM) is a non-toxic, cruciferous indole under pharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c04d6eed820bbd704be4e39eccbc52
https://eprints.ucm.es/id/eprint/70338/1/proceedings-01-00645.pdf
https://eprints.ucm.es/id/eprint/70338/1/proceedings-01-00645.pdf