Synthesis, characterization, theoretical studies and biological (antioxidant, anticancer, toxicity and neuroprotective) determinations of a copper(II) complex with 5-hydroxytryptophan

Autor: María Valcárcel, Clarisa Salado, Juan José Martínez Medina, Alberto Claudio Rizzi, Patricia A.M. Williams, Ana Laura Pérez, Luciana G. Naso, Evelina G. Ferrer, Nora Beatriz Okulik

Publikováno v: Biomedicine & Pharmacotherapy, Vol 111, Iss, Pp 414-426 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

5-Hydroxy-L-tryptophan (5-HTP) is a serotonin pathway metabolite of L-tryptophan in the brain. In the knowledge that the biological properties of some compounds can be modified upon metal complexation, a new solid metal complex, [Cu(5-hydroxytryptoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7009c3cac8d7e1277c4296a998ed4bc
https://doi.org/10.1016/j.biopha.2018.12.098

Convergence of p-stable random fractional wavelet series and some of Its properties

Autor: Juan José Martínez Medina, Fernando Dobarro, Bruno Cernuschi-Frias

For appropriate orthonormal wavelet basis {ψ^e_jk} j∈Zk∈Z^de∈{0,1}^d, constants p and γ , if I_γ denotes the Riesz fractional integral operator of order γ and (ηjke)j∈Zk∈Z^de∈{0,1}^d a sequence of independent identically distributed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8594972e10e2c23ad15dff4af1fe3ca4
https://ieeexplore.ieee.org/document/9069293/

Apigenin oxidovanadium(IV) cation interactions. Synthesis, spectral, bovine serum albumin binding, antioxidant and anticancer studies

Autor: Juan José Martínez Medina, Alberto Claudio Rizzi, Luciana G. Naso, Evelina G. Ferrer, Ana Laura Pérez, Nora Beatriz Okulik, Patricia A.M. Williams

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Continuing and expanding our previous work on flavonoid oxidovanadium(IV) (VO) metal complexes as possible anti-cancer agents, the VOapigenin compound was synthesized and characterized. An “acetylacetone-like” coordination through the C=O and O m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e6bb57ba89b2a0e0dfc1d6883272c2
https://doi.org/10.1016/j.jphotochem.2017.05.007

Improving the antidepressant action and the bioavailability of sertraline by co-crystallization with coumarin 3-carboxylate. Structural determination

Autor: Nancy Martini, Patricia A.M. Williams, Evelina G. Ferrer, Juan José Martínez Medina, Oscar E. Piro, Graciela Escudero, Ailén Natalí Rodríguez, Gustavo A. Echeverría, Carlos Horacio Laino, Libertad Leonor López Tévez

Publikováno v: Chemico-Biological Interactions. 249:46-55

To improve the antidepressant action of sertraline a new salt with coumarin-3-carboxylate anion (SerH-CCA) has been synthesized by two different methods and characterized by FTIR spectroscopy and structural determinations by X-ray diffraction methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbdf8a723da5e528f0f32f8ec1551aa
https://doi.org/10.1016/j.cbi.2016.03.010

Antitumour and Antimetastatic Effects and Safety Profile of a New Magnesium(II)-Chrysin Complex

Autor: Juan José Martínez Medina, Julia Mermot, Javier Rodríguez, Luciana G. Naso

Publikováno v: Australian Journal of Chemistry. 73:614

Chrysin is a flavone found in many plant extracts including blue passion flower, propolis and honey. The magnesium(ii) cation is an essential metal for life and it is involved in a variety of metabolic and physiological functions. Biological activiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4305df326838f38496951c66d3e9c74
https://doi.org/10.1071/ch19333