Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Juan J. Torres-Labandeira"'
Autor:
Bruno Dacunha-Marinho, Juan J. Torres-Labandeira, Pedro José Rolim Neto, Marcílio S. S. Cunha-Filho, José Lamartine Soares-Sobrinho
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 3, Pp o634-o634 (2008)
The conformation of the title compound [systematic name: N-benzyl-2-(2-nitroimidazol-1-yl)acetamide], C12H12N4O3, can be described in terms of the relative orientation of three planar fragments, the imidazol group (A), benzyl group (B), and the aceta
Externí odkaz:
https://doaj.org/article/a70af60acdb649b7ac799712360bc471
Autor:
Susana Simões, Juan J. Torres-Labandeira, Angel Concheiro, Carmen Alvarez-Lorenzo, Francisco Veiga, Ana C.F. Ribeiro
Publikováno v:
Current Topics in Medicinal Chemistry. 14:494-509
The design of syringeable cyclodextrin (CD) gels is a developing area in the drug delivery and tissue engineering fields, since they offer the possibility of being administered with minimally invasive maneuvers to form depots that can remain for prol
Autor:
Carmen Alvarez-Lorenzo, Ana C.F. Ribeiro, Angel Concheiro, Francisco Veiga, Susana Simões, Juan J. Torres-Labandeira
Publikováno v:
Macromolecular Bioscience. 13:723-734
Osteogenic/osteoinductive systems combine simvastatin, poloxamine Tetronic 908 (T908) and α-cyclodextrins (αCDs) in a supramolecular network that enhances the solubility/stability of the simvastatin hydroxy acid form and synergistically promotes os
Autor:
Lariza Darlene Santos Alves, Monica Felts de La Roca Soares, Ádley Antonini Neves de Lima, Lívio César Cunha Nunes, José Lamartine Soares-Sobrinho, Fabiana L. A. Santos, Larissa Araújo Rolim, Pedro José Rolim-Neto, Magaly Andreza Marques de Lyra, Juan J. Torres-Labandeira
Publikováno v:
Carbohydrate Polymers. 89:323-330
Benznidazole (BNZ) is the drug of choice for Chagas disease treatment, which affects about 9.8 million people worldwide. It has low solubility and high toxicity. The present study aimed to develop and characterize inclusion complexes (IC) in binary s
Autor:
Delfim Santos, Juan J. Torres-Labandeira, Andreza Maria Ribeiro, Carmen Alvarez-Lorenzo, Angel Concheiro, Francisco Veiga
Publikováno v:
Carbohydrate Polymers. 88:977-985
Carbonic anhydrase inhibitors (CAIs) are gaining interest for local treatment of glaucoma and other ocular disorders. The aim of this work was to elucidate the role of cyclodextrins (CDs) in the loading and the release rate of acetazolamide (ACT) and
Autor:
Francisco Veiga, Angel Concheiro, Juan J. Torres-Labandeira, Delfim Santos, Andreza Maria Ribeiro, Carmen Alvarez-Lorenzo
Publikováno v:
Journal of Membrane Science. 383:60-69
Biomimetic principles were applied to design N,N-dimethylacrylamide (DMA) and N-vinylpyrrolidone (NVP) hydrogels with enhanced affinity for the antiglaucoma drugs acetazolamide (ACT) and ethoxzolamide (ETOX). These inhibitors of carbonic anhydrase ar
Autor:
Delfim Santos, Angel Concheiro, Francisco Veiga, Andreza Maria Ribeiro, Carmen Alvarez-Lorenzo, Juan J. Torres-Labandeira
Publikováno v:
Biomacromolecules. 12:701-709
Hydrogels with high affinity for carbonic anhydrase (CA) inhibitor drugs have been designed trying to mimic the active site of the physiological metallo-enzyme receptor. Using hydroxyethyl methacrylate (HEMA) as the backbone component, zinc methacryl
Autor:
José Lamartine Soares-Sobrinho, Juan J. Torres-Labandeira, Pedro José Rolim-Neto, Monica Felts de La Roca Soares
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 106:319-325
Although not being the ideal drug due to its low solubility and high toxicity, the benznidazole is the drug currently chosen for Chagas disease treatment. The deep knowledge about the characteristics of the drug in addition to the knowledge of more e
Autor:
José Blanco-Méndez, Francisco J. Otero-Espinar, Juan J. Torres-Labandeira, Carmen Alvarez-Lorenzo
Publikováno v:
Journal of Drug Delivery Science and Technology. 20:289-301
Cyclodextrins are one of the most versatile aids in pharmaceutical technology, being of interest for the formulation of a wide range of delivery devices from the most classical dosage forms to the newest drug carriers. Their unique structural conform
Autor:
Juan J. Torres-Labandeira, Angel Concheiro, Carmen Alvarez-Lorenzo, Elena Lopez-Montero, Jose-Fernando Rosa dos Santos
Publikováno v:
The Open Drug Delivery Journal. 3:1-9
The aim of the present work was to develop novel hydrogels for delivering sertaconazole based on cyclodex- trins and various biocompatible polysaccharides. Sertaconazole is an antifungal agent very effective for treatment of Can- dida albicans infect