Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Juan J. Perez"'
Autor:
Maria Nuria Peralta-Moreno, Yago Mena, David Ortega-Alarcon, Ana Jimenez-Alesanco, Sonia Vega, Olga Abian, Adrian Velazquez-Campoy, Timothy M. Thomson, Marta Pinto, José M. Granadino-Roldán, Maria Santos Tomas, Juan J. Perez, Jaime Rubio-Martinez
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6119 (2024)
The development of specific antiviral therapies targeting SARS-CoV-2 remains fundamental because of the continued high incidence of COVID-19 and limited accessibility to antivirals in some countries. In this context, dark chemical matter (DCM), a set
Externí odkaz:
https://doaj.org/article/112df38d75b74c1394a53416a4e0597f
Autor:
Santiago Felici-Castell, Jaume Segura-Garcia, Juan J. Perez-Solano, Rafael Fayos-Jordan, Antonio Soriano-Asensi, Jose M. Alcaraz-Calero
Publikováno v:
Sensors, Vol 23, Iss 23, p 9585 (2023)
The proliferation and great variety of low-cost air quality (AQ) sensors, combined with their flexibility and energy efficiency, gives an opportunity to integrate them into Wireless Sensor Networks (WSN). However, with these sensors, AQ monitoring po
Externí odkaz:
https://doaj.org/article/7ea9242ab57741149b3b3d73b8f447d5
Autor:
Santiago Felici-Castell, Emilio Fernandez-Vargas, Jaume Segura-Garcia, Juan J. Perez-Solano, Rafael Fayos-Jordan, Jesus Lopez-Ballester
Publikováno v:
Applied Sciences, Vol 13, Iss 17, p 9930 (2023)
There is clear evidence of the effects of air pollution on health. In this paper, we present an innovative application designed to assess Air Quality (AQ) exposure based on the World Health Organization’s AQ Guidelines, analysing pollutants and the
Externí odkaz:
https://doaj.org/article/87f51e4a527d42b7b35a1bfa903807f0
Autor:
Rafael Fayos-Jordan, Raquel Araiz-Chapa, Santiago Felici-Castell, Jaume Segura-Garcia, Juan J. Perez-Solano, Jose M. Alcaraz-Calero
Publikováno v:
Information, Vol 14, Iss 8, p 445 (2023)
The increase and diversity of low-cost air quality (AQ) sensors, as well as their flexibility and low power consumption, offers us the opportunity to integrate them into broad AQ wireless sensor networks, with the aim of enabling real-time monitoring
Externí odkaz:
https://doaj.org/article/a468305445804a23b0ed12d8719579b3
Autor:
Ramon Roozendaal, Laura Solforosi, Daniel J. Stieh, Jan Serroyen, Roel Straetemans, Anna Dari, Muriel Boulton, Frank Wegmann, Sietske K. Rosendahl Huber, Joan E. M. van der Lubbe, Jenny Hendriks, Mathieu Le Gars, Liesbeth Dekking, Dominika N. Czapska-Casey, Nuria Guimera, Sarah Janssen, Sarah Tete, Abishek Chandrashekar, Noe B. Mercado, Jingyou Yu, Wouter Koudstaal, Juan J. Perez-Ruixo, Jerry Sadoff, Dan H. Barouch, Hanneke Schuitemaker, Roland Zahn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Several COVID-19 vaccines have received emergency approval, but durability of protection is unclear. Here, the authors describe correlates of protection (CoP) for the Ad26.COV2.S vaccine in rhesus macaques and report that CoP predict the protection o
Externí odkaz:
https://doaj.org/article/c77c130d228d404b88e0e8b1e5e20f78
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Protein-protein interactions (PPIs) mediate a large number of important regulatory pathways. Their modulation represents an important strategy for discovering novel therapeutic agents. However, the features of PPI binding surfaces make the use of str
Externí odkaz:
https://doaj.org/article/553c389edbba4a26a2d8455baedb4172
Autor:
Juan J. Perez
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 651 (2021)
Endogenous peptides are important mediators in cell communication, being consequently involved in many physiological processes. Their use as therapeutic agents is limited due to their poor pharmacokinetic profile. To circumvent this drawback, alterna
Externí odkaz:
https://doaj.org/article/b5e3797d4da94170ae13e03f9fd26936
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 257 (2020)
Covid-19 urges a deeper understanding of the underlying molecular mechanisms involved in illness progression to provide a prompt therapeutical response with an adequate use of available drugs, including drug repurposing. Recently, it was suggested th
Externí odkaz:
https://doaj.org/article/9dcc494c7c7b4ee9970bff18ca65a31c
Publikováno v:
Pharmaceuticals, Vol 13, Iss 9, p 259 (2020)
Angiotensin converting enzyme 2 (ACE2) downregulation is a key negative factor for the severity of lung edema and acute lung failure observed in patients infected with SARS-CoV-2. ACE2 downregulation affects the levels of diverse peptide mediators of
Externí odkaz:
https://doaj.org/article/56cddc8380ac4b78aef84e0b7ab4c8f8
Publikováno v:
Pharmaceuticals, Vol 13, Iss 8, p 197 (2020)
Members of the family of bombesinlike peptides exert a wide range of biological activities both at the central nervous system and in peripheral tissues through at least three G-Protein Coupled Receptors: BB1, BB2 and BB3. Despite the number of peptid
Externí odkaz:
https://doaj.org/article/bbf5f158b878474b92d77ac95ddb5775