Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Juan J. Martinez-Irujo"'
Autor:
Guillermo Zalba, Iñigo Izal, Silvia Cenoz, Juan J. Martinez-Irujo, Javier Marqués, Carlos de Miguel, Álvaro Pejenaute, Eduardo Ansorena, Adriana Cortés
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 194, p 194 (2021)
Volume 10
Issue 2
Antioxidants, Vol 10, Iss 194, p 194 (2021)
Volume 10
Issue 2
Oxidative stress constitutes a key molecular mechanism in the development of cardiovascular diseases. A potential relationship between reactive oxygen species (ROS) driven by the NADPH oxidase family (NOX) and the unfolded protein response (UPR) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250473f79b78af839644708f22ee282c
http://europepmc.org/articles/PMC7911693
http://europepmc.org/articles/PMC7911693
Autor:
Álvaro Pejenaute, Felipe Prosper, Javier Marqués, Gloria Abizanda, Guillermo Zalba, Eduardo Ansorena, Carlos de Miguel, Juan J. Martinez-Irujo, Adriana Cortés
Publikováno v:
Cells, Vol 9, Iss 3, p 637 (2020)
Cells
Volume 9
Issue 3
Cells
Volume 9
Issue 3
Oxidative stress is a main molecular mechanism that underlies cardiovascular diseases. A close relationship between reactive oxygen species (ROS) derived from NADPH oxidase (NOX) activity and the prostaglandin (PG) biosynthesis pathway has been descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62789c2a8736081b5f956588c71b5f1
https://www.mdpi.com/2073-4409/9/3/637
https://www.mdpi.com/2073-4409/9/3/637
Autor:
Enric Xipell, Tomás J. Aragón, Miguel Angel Idoate, Antonia García Garzón, Marta M. Alonso, Naiara Martinez-Velez, Frederick F. Lang, Beatriz Vera, Juan J. Martinez-Irujo, Marisol Gonzalez-Huarriz, Arlet M. Acanda, Juan Fueyo, Chris Jones, Candelaria Gomez-Manzano
Publikováno v:
Neuro-Oncology. 18:1109-1119
Background Endoplasmic reticulum (ER) stress results from protein misfolding imbalance and has been postulated as a therapeutic strategy. ER stress activates the unfolded protein response which leads to a complex cellular response, including the upre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461439f5ae145ab244a07b8e5cba1305
https://doi.org/10.1093/neuonc/now022
https://doi.org/10.1093/neuonc/now022
Autor:
Gloria Alvarez-Sola, Eduardo Ansorena, María J. Iraburu, Matías A. Avila, María J. López-Zabalza, Amaia Navarro-Corcuera, Juan J. Martinez-Irujo, Cristina Montiel-Duarte
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1866(4)
Liver damage induces hepatic stellate cells (HSC) activation, characterised by a fibrogenic, proliferative and migratory phenotype. Activated HSC are mainly regulated by transforming growth factor β 1 (TGFβ1), which increases the production of extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce0aaed8b8fee16501b93a4d5bdfd47
https://pubmed.ncbi.nlm.nih.gov/30660615
https://pubmed.ncbi.nlm.nih.gov/30660615
Autor:
Eduardo Ansorena, María J. Iraburu, María J. López-Zabalza, Guillermo Zalba, Antonia García-Garzón, Naiara Garde, Aitor Andueza, Juan J. Martinez-Irujo
Publikováno v:
Free radical biologymedicine. 126
NADPH oxidase (Nox) variants Nox1, Nox2 and Nox4 are implicated in the progression of liver fibrosis. However, the role of Nox5 is not yet known, mainly due to the lack of this enzyme in rat and mouse genomes. Here we describe the expression and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6901912a92301fba807552ca419b364
https://pubmed.ncbi.nlm.nih.gov/30036633
https://pubmed.ncbi.nlm.nih.gov/30036633
Autor:
Teresa Mòdol, Antonia García Garzón, María J. López-Zabalza, Juan J. Martinez-Irujo, María J. Iraburu, Natalia Brice, Marina Ruiz de Galarreta
Publikováno v:
Journal of Cellular Physiology. 230:546-553
The turnover of extracellular matrix (ECM) components can generate signals that regulate several cellular functions such as proliferation, differentiation, and apoptosis. During liver injury, matrix metalloproteases (MMPs) production is enhanced and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06f57282b8f9e6c61f48a6e84628c0a9
https://doi.org/10.1002/jcp.24714
https://doi.org/10.1002/jcp.24714
Autor:
Maria C. Urdaci, Ana Rouzaut, Marta Irigoyen, Juan J. Martinez-Irujo, Alicia Zuazo, Elena Ansó
Publikováno v:
Biochemical Pharmacology. 79:1600-1609
Flavonoids are a group of polyphenolic dietary compounds that have been proposed to possess chemopreventive properties against lung cancer. In this work we analyzed the effect of a group of 20 structurally related flavonoids, including flavones, flav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5856ff32cd16434b9952a128dcab50
https://doi.org/10.1016/j.bcp.2010.02.004
https://doi.org/10.1016/j.bcp.2010.02.004
Autor:
Aitor Andueza, Eduardo Ansorena, María J. López-Zabalza, Antonia García-Garzón, María J. Iraburu, Guillermo Zalba, Naiara Garde, Juan J. Martinez-Irujo
Publikováno v:
Free Radical Biology and Medicine. 120:S86
NADPH oxidase (Nox) variants Nox1, Nox2 and Nox4 have been implicated in the progression of liver fibrosis. However, the role of Nox5 is unknown, mainly due to the lack of this enzyme in rat and mouse genomes. Here we describe the expression and func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9693fc360810a6e42585cc44590aa899
https://doi.org/10.1016/j.freeradbiomed.2018.04.284
https://doi.org/10.1016/j.freeradbiomed.2018.04.284
Publikováno v:
Toxicology and Applied Pharmacology. 228:334-342
Cigarette smoking is the major preventable cause of lung cancer in developed countries. Nicotine (3-(1-methyl-2-pyrrolidinyl)-pyridine) is one of the major alkaloids present in tobacco. Besides its addictive properties, its effects have been describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3628add50485c0ae5681970e36a70b14
https://doi.org/10.1016/j.taap.2007.12.016
https://doi.org/10.1016/j.taap.2007.12.016
Autor:
E. Martínez, Elena Ansó, Mercedes Garayoa, Ana Rouzaut, Juan J. Martinez-Irujo, Marta Irigoyen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1773(6):880-890
Recent advances in our understanding of the molecular biology of lymphatic endothelial cells have revealed that these vessels, besides their known function in tissue homeostasis and immunity, constitute conduits for the tumor cells to metastasize. On
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10507f3a74002ac62e18cc5d968b9794