Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Juan J, Lafaille"'
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-9 (2021)
Measurement(s) RNA Technology Type(s) RNA sequencing Factor Type(s) genotype • diet Sample Characteristic - Organism Mus musculus Sample Characteristic - Location United States Machine-accessible metadata file describing the reported data: https://
Externí odkaz:
https://doaj.org/article/c84bcc2be65d42c19fe61a9ac3976254
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
P2X7 receptors are purinergic receptors with pro-inflammatory functions. Here, the authors show that inhibition of leukocyte P2X7 receptors reduces dendritic spine pathology and social behavioral deficits in a mouse model of Rett syndrome.
Externí odkaz:
https://doaj.org/article/0e8545eb2716481fa8f38410a3a24538
Autor:
Jin-Shu He, Sharrada Subramaniam, Vipin Narang, Kandhadayar Srinivasan, Sean P. Saunders, Daniel Carbajo, Tsao Wen-Shan, Nur Hidayah Hamadee, Josephine Lum, Andrea Lee, Jinmiao Chen, Michael Poidinger, Francesca Zolezzi, Juan J. Lafaille, Maria A. Curotto de Lafaille
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
IgE is an important mediator of protective immunity as well as allergic reaction, but how high affinity IgE antibodies are produced in memory responses is not clear. Here the authors show that IgE can be generated via class-switch recombination in Ig
Externí odkaz:
https://doaj.org/article/b0cb1457667e4bd2866daf4adcb12580
Increased generation of Foxp3+ regulatory T cells by manipulating antigen presentation in the thymus
Autor:
Jiqiang Lin, Lu Yang, Hernandez Moura Silva, Alissa Trzeciak, Yongwon Choi, Susan R. Schwab, Michael L. Dustin, Juan J. Lafaille
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The degree of Treg self-antigen reactivity varies across experimental systems. Here the authors develop a new model of skin autoimmunity and show that the size of tissue-specific Treg pool in the thymus depends on AIRE, the availability of the tissue
Externí odkaz:
https://doaj.org/article/0e0b6c0f56ef4a0d8b0da62b638522a4
Autor:
Andrey Korshunov, Alexandra L. Joyner, Reeti Mayur Sanghrajka, Antoine Tanne, Juan J. Lafaille, N. Sumru Bayin, Raquel Duque Nascimento Arifa, Veronika Kana, Zhimin Lao, Harikrishna Rallapalli, Nina Bhardwaj, Alexandre Wojcinski, Daniel H. Turnbull, Miriam Merad, I-Li Tan
Publikováno v:
Oncogene
The immune microenvironment of tumors can play a critical role in promoting or inhibiting tumor progression depending on the context. We present evidence that tumor-associated macrophages/microglia (TAMs) can promote tumor progression in the sonic he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fb59da0407e8fb823c67896327b54a
https://doi.org/10.1038/s41388-020-01536-0
https://doi.org/10.1038/s41388-020-01536-0
Autor:
Alejandra Mendoza, Béatrice Bréart, Willy D. Ramos-Perez, Lauren A. Pitt, Michael Gobert, Manjula Sunkara, Juan J. Lafaille, Andrew J. Morris, Susan R. Schwab
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1104-1110 (2012)
Plasma sphingosine-1-phosphate (S1P) regulates vascular permeability, and plasma and lymph S1P guide lymphocyte egress from lymphoid organs. S1P is made intracellularly, and little is known about how S1P is delivered into circulatory fluids. Here, we
Externí odkaz:
https://doaj.org/article/2ee8f61c589d47f4a343c861eed15190
Autor:
Jin-Shu He, Sharrada Subramaniam, Vipin Narang, Kandhadayar Srinivasan, Sean P. Saunders, Daniel Carbajo, Tsao Wen-Shan, Nur Hidayah Hamadee, Josephine Lum, Andrea Lee, Jinmiao Chen, Michael Poidinger, Francesca Zolezzi, Juan J. Lafaille, Maria A. Curotto de Lafaille
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this Article contained errors in Fig. 4 that were introduced during the production process. In panel c, the two uppermost labels ‘IgE spleen’ and ‘IgE BM’ incorrectly read ‘IgG1 spleen’ and ‘IgE1 BM
Externí odkaz:
https://doaj.org/article/c034e958099243d49d5167842016b4be
Autor:
Jamil Z. Kitoko, Juan J. Lafaille, Fanny Matheis, Bernardo S. Reis, Daniel Mucida, Katharine Lu Yang, Dan R. Littman, Camila Pereira Queiroz, Hernandez Moura Silva, Christine Ren-Fielding, Lina Kroehling, Marcelo T. Bozza
Publikováno v:
Science immunology. 6(64)
Macrophages are an essential part of tissue development and physiology. Perivascular macrophages have been described in tissues and appear to play a role in development and disease processes, although it remains unclear what the key features of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccfd7b4d0701629846eaa0c1f17e5245
https://pubmed.ncbi.nlm.nih.gov/34597120
https://pubmed.ncbi.nlm.nih.gov/34597120
Autor:
Jingyi Chi, André Báfica, Daniel Augusto Gasparin Bueno Mendes, Audrey Crane, Patricia Martin, Raquel Duque Nascimento Arifa, Daniel S. Mansur, Daniel Mucida, Hernandez Moura Silva, Bernardo S. Reis, Victor J. Torres, Juan J. Lafaille, Patricia d’Emery Alves Santos, Ken Cadwell, Gabriela F. Rodrigues-Luiz, Paul Cohen, David P. Hoytema van Konijnenburg
Publikováno v:
The Journal of Experimental Medicine
Silva et al. describe and characterize a population of adipose tissue macrophages (VAMs) that are in close contact with the vasculature and powerfully uptake blood-borne macromolecules. VAMs harbor a repair/detoxifying gene signature and adapt quickl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433f3de37d0d3a5c46798f9d7e14c98f
https://doi.org/10.1084/jem.20181049
https://doi.org/10.1084/jem.20181049
Publikováno v:
Developmental neurobiologyREFERENCES. 81(5)
Cognitive impairment is often observed in multiple sclerosis and its animal models, experimental autoimmune encephalomyelitis (EAE). Using mice with immunization-induced EAE, we have previously shown that the stability of cortical synapses is markedl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff937f4db5e82c46509846c0ccb523c
https://pubmed.ncbi.nlm.nih.gov/33949123
https://pubmed.ncbi.nlm.nih.gov/33949123