Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Juan J, Cazzulo"'
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205527 (2018)
Nowadays, most reverse genetics approaches in Trypanosoma brucei, a protozoan parasite of medical and veterinary importance, rely on pre-established cell lines. Consequently, inducible experimentation is reduced to a few laboratory strains. Here we d
Externí odkaz:
https://doaj.org/article/f509cebc40674bb0bf1ac05ebcad8402
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 79, Iss 4, Pp 649-663 (2007)
Trypanosoma cruzi is highly sensitive to oxidative stress caused by reactive oxygen species. Trypanothione, the parasite's major protection against oxidative stress, is kept reduced by trypanothione reductase, using NADPH; the major source of the red
Externí odkaz:
https://doaj.org/article/3c8564c942714b76941c04d5cd684449
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 85, Iss 4, Pp 523-529 (1990)
Externí odkaz:
https://doaj.org/article/8a3b74484df24129a75e9c47f009f645
Autor:
Dante A. Maugeri, Juan J. Cazzulo
Publikováno v:
FEMS Microbiology Letters. 234:117-123
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d385ba4fe9e4f40c0d14d9d08f1ae6c
https://doi.org/10.1111/j.1574-6968.2004.tb09522.x
https://doi.org/10.1111/j.1574-6968.2004.tb09522.x
Autor:
Juan J. Cazzulo
Publikováno v:
Current Topics in Medicinal Chemistry. 2:1261-1271
Trypanosoma cruzi, the agent of the American Trypanosomiasis, Chagas Disease, contains cysteine, serine, threonine and metallo proteinases. Aspartic proteinases have not been found so far. The most abundant among these enzymes is cruzipain, a cystein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badddd8d2888614bc2f1ee1510ab8f57
https://doi.org/10.2174/1568026023392995
https://doi.org/10.2174/1568026023392995
Autor:
Chiara, Pizzo, Cecilia, Saiz, Alan, Talevi, Luciana, Gavernet, Pablo, Palestro, Carolina, Bellera, Luis Bruno, Blanch, Diego, Benítez, Juan J, Cazzulo, Agustina, Chidichimo, Peter, Wipf, S Graciela, Mahler
Publikováno v:
Chemical biologydrug design. 77(3)
A series of 18 novel 2-hydrazolyl-4-thiazolidinones-5-carboxylic acids, amides and 5,6-α,β-unsaturated esters were synthesized, and their in vitro activity on cruzipain and T. cruzi epimastigotes was determined. Some agents show activity at 37 μm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2419e6ddfe3a4f3b2cf15bd3dcaaa468
https://pubmed.ncbi.nlm.nih.gov/21251233
https://pubmed.ncbi.nlm.nih.gov/21251233
Publikováno v:
FEMS microbiology letters. 314(1)
Comparative studies showed that, like Trypanosoma cruzi, Trypanosoma brucei exhibits functional cytosolic and mitochondrial malic enzymes (MEs), which are specifically linked to NADP. Kinetic studies provided evidence that T. cruzi and T. brucei MEs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9057ec4848179c048e00b02f3f8499bf
https://pubmed.ncbi.nlm.nih.gov/21105905
https://pubmed.ncbi.nlm.nih.gov/21105905
Cysteine proteinases of Trypanosoma cruzi: from digestive enzymes to programmed cell death mediators
Publikováno v:
Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. 30(3)
Trypanosoma cruzi, the parasite causing Chagas disease, contains a number of proteolytic enzymes. The recent completion of the genome sequence of the T. cruzi CL Brener clone suggests the presence of 70 cysteine peptidases, 40 serine peptidases (none
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76fb3434bb05a2bca76e9165d8912c75
https://pubmed.ncbi.nlm.nih.gov/17375468
https://pubmed.ncbi.nlm.nih.gov/17375468
Autor:
Dante A, Maugeri, Juan J, Cazzulo
Publikováno v:
FEMS microbiology letters. 234(1)
The pentose phosphate pathway has been studied in Trypanosoma cruzi, Clone CL Brener. Functioning of the pathway was demonstrated in epimastigotes by measuring the evolution of (14)CO(2) from [1-(14)C] or [6-(14)C]D-glucose. Glucose consumption throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db88f290d333e79c02d3f86b6ab42de7
https://pubmed.ncbi.nlm.nih.gov/15109729
https://pubmed.ncbi.nlm.nih.gov/15109729
Autor:
Williams Porcal, Paola Hernández, Mariana Boiani, Gabriela Aguirre, Lucía Boiani, Agustina Chidichimo, Juan J. Cazzulo, Nuria E. Campillo, Juan A. Paez, Ana Castro, R. Luise Krauth-Siegel, Carolina Davies, Miguel Ángel Basombrío, Mercedes González, Hugo Cerecetto
Publikováno v:
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 24, p6004-6015, 12p