Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Juan I. Bravo"'
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 22-31 (2020)
In multi-cellular organisms, the control of gene expression is key not only for development, but also for adult cellular homeostasis, and deregulation of gene expression correlates with aging. A key layer in the study of gene regulation mechanisms li
Externí odkaz:
https://doaj.org/article/ec36eb0e2d184a8da8e74a4d576b52b3
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100406- (2021)
Summary: Researchers need in vitro models that mirror the biology of organisms. Primary fibroblasts play essential roles in wound healing and are present in many tissues. They are widely used in studies of cell cycle control, reprogramming, and aging
Externí odkaz:
https://doaj.org/article/63e6e2f534e742c38aaf23bbd5872f5e
Autor:
Gabriel L. Lozano, Juan I. Bravo, Manuel F. Garavito Diago, Hyun Bong Park, Amanda Hurley, S. Brook Peterson, Eric V. Stabb, Jason M. Crawford, Nichole A. Broderick, Jo Handelsman
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The quest to manipulate microbiomes has intensified, but many microbial communities have proven to be recalcitrant to sustained change. Developing model communities amenable to genetic dissection will underpin successful strategies for shapi
Externí odkaz:
https://doaj.org/article/ebbf26fcf5c649b5b947227fd73e51c2
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011311 (2024)
Long interspersed element 1 (LINE-1; L1) are a family of transposons that occupy ~17% of the human genome. Though a small number of L1 copies remain capable of autonomous transposition, the overwhelming majority of copies are degenerate and immobile.
Externí odkaz:
https://doaj.org/article/5a13ff5896db40189d81505b73524748
Autor:
Prakroothi S. Danthi, Juan I. Bravo, Rochelle W. Lai, Erin K Donahue, Yilin Chen, Lewis T Randall, Ryan Lu, Nika Vinson, Bérénice A. Benayoun, Nirmal K Sampathkumar
Publikováno v:
Hum Genet
Although aging is a conserved phenomenon across evolutionary distant species, aspects of the aging process have been found to differ between males and females of the same species. Indeed, observations across mammalian studies have revealed the existe
Autor:
Nirmal K Sampathkumar, Minhoo Kim, Juan I. Bravo, Bérénice A. Benayoun, Ryan J Lu, Kévin Contrepois, Mathew Ellenberger, Shalina Taylor
Publikováno v:
Nat Aging
Neutrophils are the most abundant human white blood cell and constitute a first line of defense in the innate immune response. Neutrophils are short-lived cells, and thus the impact of organismal aging on neutrophil biology, especially as a function
Autor:
Pierre M. Joubert, Juan I. Bravo, Melanie B. Abrams, Rachel B. Brem, Carly V. Weiss, Claire A. Dubin, Faisal AlZaben
Publikováno v:
G3: Genes|Genomes|Genetics
Many familiar traits in the natural world—from lions’ manes to the longevity of bristlecone pine trees—arose in the distant past, and have long since fixed in their respective species. A key challenge in evolutionary genetics is to figure out h
Publikováno v:
Development. 147
Our understanding of the molecular regulation of aging and age-related diseases is still in its infancy, requiring in-depth characterization of the molecular landscape shaping these complex phenotypes. Emerging classes of molecules with promise as ag
Publikováno v:
Transl Med Aging
Translational Medicine of Aging, Vol 4, Iss, Pp 22-31 (2020)
Translational Medicine of Aging, Vol 4, Iss, Pp 22-31 (2020)
In multi-cellular organisms, the control of gene expression is key not only for development, but also for adult cellular homeostasis, and deregulation of gene expression correlates with aging. A key layer in the study of gene regulation mechanisms li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f0c98798b517135fc5e08ffb441664
https://europepmc.org/articles/PMC7252472/
https://europepmc.org/articles/PMC7252472/
In multi-cellular organisms, the control of gene expression is key not only for development, but also for adult cellular homeostasis, and deregulation of gene expression correlates with aging. A key layer in the study of gene regulation mechanisms li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7bfd2e89fb9bd18ffb31f11079d5552