Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Juan I. Blanco Capurro"'
Autor:
Kevin P. Guay, Roberta Ibba, J.L. Kiappes, Snežana Vasiljević, Francesco Bonì, Maria De Benedictis, Ilaria Zeni, James D. Le Cornu, Mario Hensen, Anu V. Chandran, Anastassia L. Kantsadi, Alessandro T. Caputo, Juan I. Blanco Capurro, Yusupha Bayo, Johan C. Hill, Kieran Hudson, Andrea Lia, Juliane Brun, Stephen G. Withers, Marcelo Martí, Emiliano Biasini, Angelo Santino, Matteo De Rosa, Mario Milani, Carlos P. Modenutti, Daniel N. Hebert, Nicole Zitzmann, Pietro Roversi
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107919- (2023)
Summary: Misfolded glycoprotein recognition and endoplasmic reticulum (ER) retention are mediated by the ER glycoprotein folding quality control (ERQC) checkpoint enzyme, UDP-glucose glycoprotein glucosyltransferase (UGGT). UGGT modulation is a promi
Externí odkaz:
https://doaj.org/article/65e937022caf475ebc2513beca012f73
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Galectins (formerly known as “S-type lectins”) are a subfamily of soluble proteins that typically bind β-galactoside carbohydrates with high specificity. They are present in many forms of life, from nematodes and fungi to animals, where they per
Externí odkaz:
https://doaj.org/article/754c793355b4420786be1721f1e58ff5
Autor:
Kevin P. Guay, Roberta Ibba, JL Kiappes, Maria De Benedictis, Ilaria Zeni, James D. Le Cornu, Mario Hensen, Anu V. Chandran, Anastassia L. Kantsadi, Alessandro T. Caputo, Juan I. Blanco Capurro, Yusupha Bayo, Johan C. Hill, Kieran Hudson, Andrea Lia, Snežana Vasiljević, Carlos P. Modenutti, Stephen G. Withers, Marcelo Martí, Emiliano Biasini, Angelo Santino, Daniel N. Hebert, Nicole Zitzmann, Pietro Roversi
Publikováno v:
SSRN Electronic Journal.
The Endoplasmic Reticulum (ER) glycoprotein folding Quality Control (ERQC) machinery aids folding of glycoproteins in the ER. Misfolded glycoprotein recognition and ER-retention is mediated by the ERQC checkpoint enzyme, the 170 kDa UDP-Glucose glyco
Autor:
Carlos P. Modenutti, Dominic S. Alonzi, Roberta Ibba, Anu V. Chandran, Gabor Tax, Thomas Waksman, Andrea Lia, Angelo Santino, Jonathan Rushton, Abhinav Kumar, Snežana Vasiljević, Marcelo A. Martí, Mauro N. Song, Mario Hensen, Lucia Marti, Juan I. Blanco Capurro, Pietro Roversi, Simone Rubichi, Nicole Zitzmann, Johan C. Hill
Publikováno v:
Structure(London, England:1993)
Structure (Lond.) 29 (2021): 357–370.e9. doi:10.1016/j.str.2020.11.017
info:cnr-pdr/source/autori:Modenutti C.P.; Blanco Capurro J.I.; Ibba R.; Alonzi D.S.; Song M.N.; Vasiljevic S.; Kumar A.; Chandran A.V.; Tax G.; Marti L.; Hill J.C.; Lia A.; Hensen M.; Waksman T.; Rushton J.; Rubichi S.; Santino A.; Marti M.A.; Zitzmann N.; Roversi P./titolo:Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase/doi:10.1016%2Fj.str.2020.11.017/rivista:Structure (Lond.)/anno:2021/pagina_da:357/pagina_a:370.e9/intervallo_pagine:357–370.e9/volume:29
Structure (Lond.) 29 (2021): 357–370.e9. doi:10.1016/j.str.2020.11.017
info:cnr-pdr/source/autori:Modenutti C.P.; Blanco Capurro J.I.; Ibba R.; Alonzi D.S.; Song M.N.; Vasiljevic S.; Kumar A.; Chandran A.V.; Tax G.; Marti L.; Hill J.C.; Lia A.; Hensen M.; Waksman T.; Rushton J.; Rubichi S.; Santino A.; Marti M.A.; Zitzmann N.; Roversi P./titolo:Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase/doi:10.1016%2Fj.str.2020.11.017/rivista:Structure (Lond.)/anno:2021/pagina_da:357/pagina_a:370.e9/intervallo_pagine:357–370.e9/volume:29
Summary UDP-glucose:glycoprotein glucosyltransferase (UGGT) flags misfolded glycoproteins for ER retention. We report crystal structures of full-length Chaetomium thermophilum UGGT (CtUGGT), two CtUGGT double-cysteine mutants, and its TRXL2 domain tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba809d96b8e8640d443e2d32e298256
https://ora.ox.ac.uk/objects/uuid:7ebfcefe-a06c-4124-aabf-01bc5589b350
https://ora.ox.ac.uk/objects/uuid:7ebfcefe-a06c-4124-aabf-01bc5589b350
Autor:
Gabor Tax, Angelo Santino, Anu V. Chandran, Snežana Vasiljević, Thomas Waksman, Roberta Ibba, Abhinav Kumar, Lucia Marti, Dominic S. Alonzi, Nicole Zitzmann, Juan I. Blanco Capurro, Johan C. Hill, Marcelo A. Martí, Mario Hensen, Jonathan Rushton, Carlos P. Modenutti, Andrea Lia, Pietro Roversi, Simone Rubichi
Publikováno v:
SSRN Electronic Journal.
UDP-glucose: glycoprotein glucosyltransferase (UGGT) is the glycoprotein folding checkpoint in the eukaryotic glycoprotein secretory pathway. The enzyme detects misfolded glycoproteins in the Endoplasmic Reticulum, and flags them for retention by re-
Autor:
Juan I. Blanco Capurro, Mariano C. González Lebrero, Marcelo A. Martí, Chad W. Hopkins, Gustavo Pierdominici Sottile, Adrian E. Roitberg
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Understanding enzymatic reactions with atomic resolution has proven in recent years to be of tremendous interest for biochemical research, and thus, the use of QM/MM methods for the study of reaction mechanisms is experiencing a continuous growth. Gl