Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Juan Francisco Miquel, P."'
Autor:
Tamara Pérez-Jeldres, Fabien Magne, Gabriel Ascui, Danilo Alvares, Matias Orellana, Manuel Alvarez-Lobos, Cristian Hernandez-Rocha, Lorena Azocar, Nataly Aguilar, Alberto Espino, Ricardo Estela, Sergio Escobar, Alejandra Zazueta, Pablo Baez, Verónica Silva, Andres De La Vega, Elizabeth Arriagada, Carolina Pavez-Ovalle, Alejandro Díaz-Asencio, Dante Travisany, Juan Francisco Miquel, Eduardo J. Villablanca, Mitchell Kronenberg, María Leonor Bustamante
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Background and aimsLatin American populations remain underrepresented in genetic studies of inflammatory bowel diseases (IBDs). Most genetic association studies of IBD rely on Caucasian, African, and Asian individuals. These associations have yet to
Externí odkaz:
https://doaj.org/article/7ffc78ebfeca4fa88dee089835f2fae8
Autor:
Gareth I. Owen, Miguel Cordova-Delgado, Bernabé I. Bustos, Leslie C. Cerpa, Pamela Gonzalez, Sebastián Morales-Pison, Benjamín Garcia-Bloj, Marcelo Garrido, Juan Francisco Miquel, Luis A. Quiñones
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 561 (2024)
Background: Pharmacogenomic knowledge as a biomarker for cancer care has transformed clinical practice, however, as current guidelines are primarily derived from Eurocentric populations, this limits their application in Latin America, particularly am
Externí odkaz:
https://doaj.org/article/7c33563f4b7e4080b31af09370753e1e
Autor:
Miguel Cordova-Delgado, María Loreto Bravo, Elisa Cumsille, Charlotte N. Hill, Matías Muñoz-Medel, Mauricio P. Pinto, Ignacio N. Retamal, María A. Lavanderos, Juan Francisco Miquel, Maria Rodriguez-Fernandez, Yuwei Liao, Zhiguang Li, Alejandro H. Corvalán, Ricardo Armisén, Marcelo Garrido, Luis A. Quiñones, Gareth I. Owen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
Abstract Background Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe fluoropyrimidine toxicity wit
Externí odkaz:
https://doaj.org/article/63e96e3bc013444db64e630114bf6b8d
Autor:
Lorena Rosa, Lorena Lobos‐González, Natalia Muñoz‐Durango, Patricia García, Carolina Bizama, Natalia Gómez, Ximena González, Ignacio A. Wichmann, Nicolás Saavedra, Francisca Guevara, Jaime Villegas, Marco Arrese, Catterina Ferreccio, Alexis M. Kalergis, Juan Francisco Miquel, Jaime A. Espinoza, Juan C. Roa
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2834-2852 (2020)
Gallbladder stones (cholecystolithiasis) are the main risk factor for gallbladder cancer (GBC), a lethal biliary malignancy with poor survival rates worldwide. Gallbladder stones are thought to damage the gallbladder epithelium and trigger chronic in
Externí odkaz:
https://doaj.org/article/555482fa74f1498e9ea86a122d8b51ed
Akademický článek
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Autor:
Constanza Martínez-Valdebenito, Jenniffer Angulo, Nicole Le Corre, Claudia Marco, Cecilia Vial, Juan Francisco Miquel, Jaime Cerda, Gregory Mertz, Pablo Vial, Marcelo Lopez-Lastra, Marcela Ferrés
Publikováno v:
Viruses, Vol 11, Iss 2, p 169 (2019)
The Andes Orthohantavirus (ANDV), which causes the hantavirus cardiopulmonary syndrome, enters cells via integrins, and a change from leucine to proline at residue 33 in the PSI domain (L33P), impairs ANDV recognition. We assessed the association bet
Externí odkaz:
https://doaj.org/article/6e3e5c61e5bf4890a7bebd770bb6d7ce
Autor:
Alberto Espino, Andrea Villagrán, Valeska Vollrath, Paulina Hanckes, Roberto Salas, Andrea Farah, Nancy Solís, Margarita Pizarro, Alex Escalona, Camilo Boza, Gustavo Pérez, Gonzalo Carrasco, Oslando Padilla, Juan Francisco Miquel, Flavio Nervi, Norberto C. Chavez-Tapia, Juan Pablo Arab, Manuel Álvarez-Lobos, Marco Arrese, Arnoldo Riquelme
Publikováno v:
Annals of Hepatology, Vol 10, Iss 4, Pp 493-501 (2011)
Background. The plasminogen activator inhibitor type-1 (PAI-1) has been implicated in the regulation of fibrinolysis and extracellular matrix components. The single base pair guanine insertion/deletion polymorphism (4G/5G) within the promoter region
Externí odkaz:
https://doaj.org/article/2ae28f0dfd2d45569c44f46a637dbec9
Publikováno v:
Revista Médica Clínica Las Condes, Vol 22, Iss 4, Pp 486-491 (2011)
Chile tiene la mayor tasa de incidencia de cáncer de vesícula biliar (CVB) en el mundo (> 30 por 100.000). Siendo la principal causa de muerte por cáncer entre las mujeres chilenas. Para diseñar estrategias de prevención y diagnóstico precoz de
Externí odkaz:
https://doaj.org/article/87395dc657cd4dbc987fb7c7e1f25900
Autor:
Juan G. Mella, Ramin Schirin-Sokhan, Attilio Rigotti, Fernando Pimentel, Luis Villarroel, Hermann E. Wasmuth, Tilman Sauerbruch, Flavio Nervi, Frank Lammert, Juan Francisco Miquel
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 6, Pp 1378-1385 (2007)
Apolipoprotein E (apoE) isoforms are genetic determinants of interindividual variations in lipid metabolism. To assess whether apoE is a genetic risk factor for cholesterol gallstone disease (GD), we analyzed apoE variants in populations from Chile a
Externí odkaz:
https://doaj.org/article/387caafd0f8441bba955e61d97d39dab
Autor:
Robinson González, Alejandro Soza, Verónica Hernández, Rosa M. Pérez, Manuel Álvarez, Arturo Morales, Marco Arellano, Arnoldo Riquelme, Paola Viviani, Carmen Covarrubias, Marco Arrese, Juan Francisco Miquel, Flavio Nervi
Publikováno v:
Annals of Hepatology, Vol 4, Iss 2, Pp 127-130 (2005)
Chronic hepatitis C is a major cause of liver-related morbidity and mortality. Epidemiological data regarding this infection in developing countries is scanty. Methods: Prevalence of hepatitis C (HCV) infection was investigated in a random sample of
Externí odkaz:
https://doaj.org/article/d82961ca7d954e84883372056d7d8f35