Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Juan Fernández-Recio"'
Autor:
Elena Erausquin, Adela Rodríguez-Fernández, Luis Ángel Rodríguez-Lumbreras, Juan Fernández-Recio, María Gilda Dichiara-Rodríguez, Jacinto López-Sagaseta
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-6 (2024)
Abstract The endothelial protein C receptor (EPCR) is a fundamental component of the vascular system in mammals due to its contribution in maintaining blood in a non-prothrombotic state, which is crucial for overall life development. It accomplishes
Externí odkaz:
https://doaj.org/article/a432af67f6bd4dffac723ce3606344ae
Autor:
Luis Angel Rodríguez-Lumbreras, Brian Jiménez-García, Silvia Giménez-Santamarina, Juan Fernández-Recio
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Proteins and nucleic acids are essential biological macromolecules for cell life. Indeed, interactions between proteins and DNA regulate many biological processes such as protein synthesis, signal transduction, DNA storage, or DNA replication and rep
Externí odkaz:
https://doaj.org/article/16eae038fc514e338ef924ba7bea44f7
Autor:
Mireia Rosell, Juan Fernández-Recio
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3750-3761 (2020)
Protein-protein interactions play an essential role in many biological processes, and their perturbation is a major cause of disease. The use of small molecules to modulate them is attracting increased attention, but protein interfaces generally do n
Externí odkaz:
https://doaj.org/article/9148bbdc7ed94273bda14907c8aa45f4
Autor:
Ekaitz Errasti-Murugarren, Joana Fort, Paola Bartoccioni, Lucía Díaz, Els Pardon, Xavier Carpena, Meritxell Espino-Guarch, Antonio Zorzano, Christine Ziegler, Jan Steyaert, Juan Fernández-Recio, Ignacio Fita, Manuel Palacín
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
L-Amino acid Transporters (LATs) are asymmetric amino acid exchangers. Here the authors determine the crystal structure of a prokaryotic LAT, the alanine-serine-cysteine exchanger (BasC) and identify key residues for asymmetric substrate interaction
Externí odkaz:
https://doaj.org/article/02f00387781745f491d1d369e1db2215
Autor:
Juan Fernández-Recio
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 6, p 1825 (2020)
A previously developed mechanistic model of COVID-19 transmission has been adapted and applied here to study the evolution of the disease and the effect of intervention measures in some European countries and territories where the disease has had a m
Externí odkaz:
https://doaj.org/article/b02412d153fb4b539df9cf85172f5626
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183643 (2017)
Next-generation sequencing (NGS) technologies are providing genomic information for an increasing number of healthy individuals and patient populations. In the context of the large amount of generated genomic data that is being generated, understandi
Externí odkaz:
https://doaj.org/article/eaed9a0146184272984b700fc7e29de1
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1583 (2019)
One of the known potential effects of disease-causing amino acid substitutions in proteins is to modulate protein-protein interactions (PPIs). To interpret such variants at the molecular level and to obtain useful information for prediction purposes,
Externí odkaz:
https://doaj.org/article/b70ae63318964483a6eb653d3322d5ad
Publikováno v:
Advances and Applications in Bioinformatics and Chemistry, Vol 2009, Iss default, Pp 101-123 (2009)
Solène Grosdidier1, Max Totrov2, Juan Fernández-Recio11Life Sciences Department, Barcelona Supercomputing Center, Barcelona, Spain; 2Molsoft LLC, La Jolla, CA, USAAbstract: In recent years, protein–protein interactions are becoming the object of
Externí odkaz:
https://doaj.org/article/e91bbaa3961c48dc8846f551d88f340d
Autor:
Juan Fernández-Recio
Publikováno v:
EBioMedicine, Vol 9, Iss C, Pp 7-8 (2016)
Externí odkaz:
https://doaj.org/article/d1e805dc64264dbabfc8b51c9801af5e
Autor:
Yang Chen, Igor Tascón, M. Ramona Neunuebel, Chiara Pallara, Jacqueline Brady, Lisa N. Kinch, Juan Fernández-Recio, Adriana L. Rojas, Matthias P. Machner, Aitor Hierro
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/89598b7102c7417a93e7a482b85e7057