Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Juan F Gomez"'
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217993 (2019)
BackgroundHeart failure (HF) is characterized, among other factors, by a progressive loss of contractile function and by the formation of an arrhythmogenic substrate, both aspects partially related to intracellular Ca2+ cycling disorders. In failing
Externí odkaz:
https://doaj.org/article/5afef8d64cf147aea55c12fba4d22975
Publikováno v:
AIMS Mathematics, Vol 9, Iss 9, Pp 24247-24270 (2024)
A fundamental assumption in addressing real-world problems is acknowledging the presence of uncertainty and dynamism. Dismissing these factors can lead to the formulation of an optimal solution for an entirely different problem. This paper presents a
Externí odkaz:
https://doaj.org/article/826feae39f8d42129b8ac05f32fc529f
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103273 (2014)
Heart failure is operationally defined as the inability of the heart to maintain blood flow to meet the needs of the body and it is the final common pathway of various cardiac pathologies. Electrophysiological remodeling, intercellular uncoupling and
Externí odkaz:
https://doaj.org/article/0a3697143a3b4919b0010be269ca478c
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106602 (2014)
Heart failure is a final common pathway or descriptor for various cardiac pathologies. It is associated with sudden cardiac death, which is frequently caused by ventricular arrhythmias. Electrophysiological remodeling, intercellular uncoupling, fibro
Externí odkaz:
https://doaj.org/article/fdfe6027738849bfb910d07b800dbd81
Autor:
Beatriz Trenor, Karen Cardona, Juan F Gomez, Sridharan Rajamani, Jose M Ferrero, Luiz Belardinelli, Javier Saiz
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32659 (2012)
Heart failure constitutes a major public health problem worldwide. The electrophysiological remodeling of failing hearts sets the stage for malignant arrhythmias, in which the role of the late Na(+) current (I(NaL)) is relevant and is currently under
Externí odkaz:
https://doaj.org/article/82641182e1904377907f2bf61fb91e47
Publikováno v:
Mathematics, Vol 12, Iss 11, p 1758 (2024)
The team orienteering problem (TOP) is a well-studied optimization challenge in the field of Operations Research, where multiple vehicles aim to maximize the total collected rewards within a given time limit by visiting a subset of nodes in a network
Externí odkaz:
https://doaj.org/article/e064e9ccc1ef4e6a9b3ff4806bee4c69
Publikováno v:
Mathematics, Vol 12, Iss 6, p 909 (2024)
In an effort to balance the distribution of services across a given territory, dispersion and diversity models typically aim to maximize the minimum distance between any pair of facilities. Specifically, in the capacitated dispersion problem (CDP), e
Externí odkaz:
https://doaj.org/article/ef2ff072f94140a2a1aeadcdd31e95d6
Publikováno v:
Algorithms, Vol 16, Iss 12, p 532 (2023)
The capacitated dispersion problem, which is a variant of the maximum diversity problem, aims to determine a set of elements within a network. These elements could symbolize, for instance, facilities in a supply chain or transmission nodes in a telec
Externí odkaz:
https://doaj.org/article/97244df87b8248839e1d2ffdc3daa806
Autor:
Edison F. Carpio, Juan F. Gomez, Rafael Sebastian, Alejandro Lopez-Perez, Eduardo Castellanos, Jesus Almendral, Jose M. Ferrero, Beatriz Trenor
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Patients suffering from heart failure and left bundle branch block show electrical ventricular dyssynchrony causing an abnormal blood pumping. Cardiac resynchronization therapy (CRT) is recommended for these patients. Patients with positive therapy r
Externí odkaz:
https://doaj.org/article/55aec4b29851441790eecdcf661ff91a
Publikováno v:
2021 Winter Simulation Conference (WSC).