Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Juan F, Santibanez"'
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25081- (2024)
Myeloid malignancies are clonal disorders of the progenitor cells or hematopoietic stem cells, including acute myeloid leukemia, myelodysplastic syndromes, myeloproliferative malignancies, and chronic myelomonocytic leukemia. Myeloid neoplastic cells
Externí odkaz:
https://doaj.org/article/b10458d431124248bf80461df02859cf
Autor:
Puthiyavalappil Rasin, Sabeel M. Basheer, Jebiti Haribabu, K.N. Aneesrahman, Vipin Manakkadan, Vishnunarayanan Namboothiri Vadakkedathu Palakkeezhillam, Nattamai Bhuvanesh, Cesar Echeverria, Juan F. Santibanez, Anandaram Sreekanth
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e24077- (2024)
A novel Coumarin-based 1,2-pyrazole, HCPyTSC is synthesised and characterized. The chemosensor has been shown to have efficient colourimetric and fluorescence sensing capabilities for the quick and selective detection of fluoride and copper ions. At
Externí odkaz:
https://doaj.org/article/2ac1114b22e54b8881f9b88ed0c6d6f7
Autor:
Cesar Echeverría, Aldo Martin, Felipe Simon, Cristian O. Salas, Mariajesus Nazal, Diego Varela, Ramón A. Pérez-Castro, Juan F. Santibanez, Ricardo O. Valdés-Valdés, Oscar Forero-Doria, Javier Echeverría
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: There is abundant ethnopharmacological evidence the uses of regarding Solanum species as antitumor and anticancer agents. Glycoalkaloids are among the molecules with antiproliferative activity reported in these species.Purpose: To evaluat
Externí odkaz:
https://doaj.org/article/ded390d9bcbc4197b0bf58cb25b3f7ed
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1543 (2023)
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 and ranking as the second-leading cause of death in economically developed countries [...]
Externí odkaz:
https://doaj.org/article/2df70f15ee9549c384779ebec30a414b
Autor:
Yolanda Prado, Cesar Echeverría, Carmen G. Feijóo, Claudia A. Riedel, Claudio Cabello-Verrugio, Juan F. Santibanez, Felipe Simon
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 659 (2023)
Sepsis syndrome develops through enhanced secretion of pro-inflammatory cytokines and the generation of reactive oxygen species (ROS). Sepsis syndrome is characterized by vascular hyperpermeability, hypotension, multiple organ dysfunction syndrome (M
Externí odkaz:
https://doaj.org/article/6d60f5fef043430aa5165c745528ebb0
Autor:
Dusan Ruzic, Bernhard Ellinger, Nemanja Djokovic, Juan F. Santibanez, Sheraz Gul, Milan Beljkas, Ana Djuric, Arasu Ganesan, Aleksandar Pavic, Tatjana Srdic-Rajic, Milos Petkovic, Katarina Nikolic
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2600 (2022)
Isoform-selective histone deacetylase (HDAC) inhibition is promoted as a rational strategy to develop safer anti-cancer drugs compared to non-selective HDAC inhibitors. Despite this presumed benefit, considerably more non-selective HDAC inhibitors ha
Externí odkaz:
https://doaj.org/article/9553b260a016413db518fa18e856ad8a
Publikováno v:
Analytical Cellular Pathology, Vol 2021 (2021)
Besides transformed cells, the tumors are composed of various cell types that contribute to undesirable tumor progression. Tumor-associated macrophages (TAMs) are the most abundant innate immune cells in the tumor microenvironment (TME). Within the T
Externí odkaz:
https://doaj.org/article/25c7e3d6672948f0b4bb2754a8308adc
Autor:
Dragoslava Đikić, Andrija Bogdanović, Dragana Marković, Olivera Mitrović-Ajtić, Tijana Subotički, Miloš Diklić, Milica Vukotić, Teodora Dragojević, Emilija Živković, Juan F. Santibanez, Vladan P. Čokić
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 247 (2022)
Chronic inflammation is characterized by the production of reactive oxygen species (ROS), reactive nitrogen species, and inflammatory cytokines in myeloproliferative neoplasms (MPNs). In addition to these parameters, the aim of this study was to anal
Externí odkaz:
https://doaj.org/article/6db52a5140744ce7b434d052922ca4c8
Autor:
Dusan Ruzic, Nemanja Djoković, Tatjana Srdić-Rajić, Cesar Echeverria, Katarina Nikolic, Juan F. Santibanez
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 209 (2022)
The dysregulation of gene expression is a critical event involved in all steps of tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene expression due to the abnormal activation of histone deacetylases (HDAC) have been rep
Externí odkaz:
https://doaj.org/article/4f669d97d82d4339b71747758c21b181
Autor:
Tijana Subotički, Olivera Mitrović Ajtić, Dragoslava Djikić, Marijana Kovačić, Juan F. Santibanez, Milica Tošić, Vladan P. Čokić
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1562 (2021)
In several systems, hydroxyurea has been shown to trigger nitric oxide (NO) release or activation of NO synthase (NOS). To elucidate this duality in its pharmacological effects, during myelosuppression, we individually examined hydroxyurea’s (NO re
Externí odkaz:
https://doaj.org/article/d9113f8dbc9b4b628f010db3de4ea6ef