Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Juan F, Miquel"'
Autor:
José P. Miranda, Ana Pereira, Camila Corvalán, Juan F. Miquel, Gigliola Alberti, Juan C. Gana, José L. Santos
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Gene variants in the UGT1A1 gene are strongly associated with circulating bilirubin levels in several populations, as well as other variants of modest effect across the genome. However, the effects of such variants are unknown regarding the Native Am
Externí odkaz:
https://doaj.org/article/549c2a7a7155479085641b2e3be5986d
Autor:
Francisco Barrera, Lorena Azocar, Héctor Molina, Kurt A. Schalper, Marcia Ocares, Jessica Liberona, Luis Villarroel, Fernando Pimentel, Rosa M. Pérez-Ayuso, Flavio Nervi, Albert K. Groen, Juan F. Miquel
Publikováno v:
Annals of Hepatology, Vol 14, Iss 5, Pp 710-721 (2015)
Background and rationale for the study. FGF19/15 is a gut-derived hormone presumably governing bile acid (BA) synthesis and gallbladder (GB) refilling. FGF19 mRNA is present in human GB cholangiocytes (hGBECs); however, the physiological significance
Externí odkaz:
https://doaj.org/article/4f36d2ee70f3407485f572df30b96ee5
Publikováno v:
Annals of Hepatology, Vol 4, Iss 3, Pp 192-199 (2005)
Background: Gallbladder carcinoma (GBC) is a frequent neoplasm in Hispanic and native American populations. GBC is preceded by gallstones, chronic cholecystitis and dysplastic changes of the gallbladder epithelium. The knowledge of the molecular even
Externí odkaz:
https://doaj.org/article/6650600bcb6843b9914c8c59ba506935
Autor:
Jill Koshiol, Aniela Wozniak, Paz Cook, Christina Adaniel, Johanna Acevedo, Lorena Azócar, Ann W. Hsing, Juan C. Roa, Marcela F. Pasetti, Juan F. Miquel, Myron M. Levine, Catterina Ferreccio, the Gallbladder Cancer Chile Working Group
Publikováno v:
Cancer Medicine, Vol 5, Iss 11, Pp 3310-3235 (2016)
Abstract In Chile, where gallbladder cancer (GBC) rates are high and typhoid fever was endemic until the 1990s, we evaluated the association between Salmonella enterica serovar Typhi (S. Typhi) antibodies and GBC. We tested 39 GBC cases, 40 gallstone
Externí odkaz:
https://doaj.org/article/8e9fe5cb259c4d698c67bd4eb0e85ef7
Publikováno v:
Human Pathology. 30:21-25
Although most gallbladder carcinomas evolve from dysplasia and carcinoma in situ, the role of gallbladder adenomas in the pathogenesis of gallbladder carcinoma is still controversial. A series of molecular changes including loss of heterozygosity (LO
Autor:
Luis, Ibáñez, Ruth, Sanzana, Carlos, Salas, Claudia, Navarrete, Ricardo, Cartes-Velásquez, Angélica, Rainqueo, Tamara, Jara, Francisco, Pérez-Bravo, Natalia, Ulloa, Carlos, Calvo, Juan F, Miquel, Carlos, Celis-Morales
Publikováno v:
Revista medica de Chile. 142(8)
Metabolic Syndrome (MS) increases the risk of diabetes and mortality associated with cardiovascular disease. However, the prevalence of MS could differ by ethnicity and lifestyle factors.To determine the prevalence of MS in Mapuche individuals living
Autor:
Luis, Méndez, Marcela, Lagoa, Teresa, Quiroga, Paula, Margozzini, Lorena, Azócar, Héctor R, Molina, Alejandra, Vera, Luis, Villarroel, Marco, Arrese, Jochen, Hampe, Stephan, Buch, Juan F, Miquel
Publikováno v:
Revista medica de Chile. 141(10)
In Europeans the TATA box TA7 repeat promoter variant in the UGT1A1 gene (UGT1A1*28) is the major determinant of bilirubin levels.To study the prevalence of Gilbert Syndrome (GS) and its genetic determinants in Chile.Three different studies were cond
Autor:
Goodarz, Danaei, Gitanjali, M Singh, Christopher, J Paciorek, John, K Lin, Melanie, J Cowan, Mariel, M Finucane, Farshad, Farzadfar, Gretchen, A Stevens, Leanne, M Riley, Yuan, Lu, Mayuree, Rao, Majid, Ezzati, Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group: Writing and Global Analysis Group: Goodarz Danaei, Paciorek, Christopher J., Lin, John K., Cowan, Melanie J., Finucane, Mariel M., Stevens, Gretchen A., Riley, Leanne M., Peres, Cynthia Pérez, Román Pérez-Fernández, Rafael Pichardo, Hwee Pin Phua, Majid Ezzati. Contributed equally to the research and manuscript and listed in alphabetic order. Country Data Group: Geir Aamodt, Ziad Abdeen, Nabila A. Abdella, Hanan F. Abdul Rahim, Juliet Addo, Wichai Aekplakorn, Mustafa M. Afifi, Enrico Agabiti-Rosei, Carlos A. Aguilar Salinas, Charles Agyemang, Mohamed M. Ali, Mohannad Al-Nsour, Abdul R. Al-Nuaim, Ramachandran Ambady, Pertti Aro, Fereidoun Azizi, Carlo M. Barbagallo, Marco Antonio M. Barbieri, Alberto Barceló, Sandhi M. Barreto, Henrique Barros, Leonelo E. Bautista, Athanase Benetos, Peter Bjerregaard, Cecilia Björkelund, Simona Bo, Martin Bobak, Enzo Bonora, Babu V. Bontha, Manuel A. Botana, Pascal Bovet, Juergen Breckenkamp, Monique M. Breteler, Grazyna Broda, Ian J. Brown, Michael Bursztyn, Antonio Cabrera de León, Hannia Campos, Francesco P. Cappuccio, Vincenzo Capuano, Edoardo Casiglia, Maurizio Castellano, Katia Castetbon, Luis Cea, ChihJen Chang, Noureddine Chaouki, Somnath Chatterji, Chien-Jen Chen, Zhengming Chen, Jin-Su Choi, Lily Chua, Renata Cífková, Linda J. Cobiac, Richard S. Cooper, Anna Maria Corsi, Michael C. Costanza, Cora L. Craig, Rachel S. Dankner, Saeed Dastgiri, Elias Delgado, Gonul Dinc, Yasufumi Doi, Guang-Hui Dong, Eleonora Dorsi, Nico Dragano, Adam Drewnowski, Robert W. Eggertsen, Paul Elliott, Anders Engeland, Cihangir Erem, Alireza Esteghamati, Caroline H. D. Fall, Jian-Gao Fan, Catterina Ferreccio, Leopold Fezeu, Josélia O. Firmo, Hermes J. Florez, Nélida S. Fornés, F. Gerry R. Fowkes, Guido Franceschini, Fredrik Frisk, Flávio D. Fuchs, Eva L. Fuller, Linn Getz, Simona Giampaoli, Luis F. Gómez, Juan M. Gomez-Zumaquero, Sidsel Graff-Iversen, Janet F. Grant, Ramiro Guerrero Carvajal, Martin C. Gulliford, Rajeev Gupta, Prakash C. Gupta, Oye Gureje, Tine W. Hansen, Jun Hata, Jiang He, Noor Heim, Joachim Heinrich, Tomas Hemmingsson, Anselm Hennis, William H. Herman, Victor M. Herrera, Suzanne Ho, Michelle Holdsworth, Gunilla Hollman Frisman, Wilma M. Hopman, Akhtar Hussain, Abdullatif Husseini, M. Mohsen Ibrahim, Nayu Ikeda, Bjarne K. Jacobsen, Hashem Y. Jaddou, Tazeen H. Jafar, Mohsen Janghorbani, Grazyna Jasienska, Michel R. Joffres, Jost B. Jonas, Othman A. Kadiki, Ofra Kalter-Leibovici, Raoul M. Kamadjeu, Ioannis Karalis, Mika J. Kastarinen, Joanne Katz, Lital Keinan-Boker, Paul Kelly, Omid Khalilzadeh, Young-Ho Khang, Stefan Kiechl, Ki Woong Kim, Yutaka Kiyohara, Junji Kobayashi, Maressa P. Krause, Růžena Kubínová, Pawel Kurjata, Yadlapalli S. Kusuma, Tai Hing Lam, Arnulf Langhammer, Carlene M. M. Lawes, Cai Le, Jeannette Lee, Claire Lévy-Marchal, Yanping Li, Yuqiu Li, Stephen Lim, T. O. Lim, Xu Lin, Cheng-Chieh Lin, Hsien-Ho Lin, Lars Lind, Lauren Lissner, Xiaoqing Liu, Patricio Lopez-Jaramillo, Roberto Lorbeer, Guansheng Ma, Stefan Ma, Francesc Macià, David R. MacLean, Stefania Maggi, Dianna J. Magliano, Marcia Makdisse, Giuseppe Mancia, Toshifumi Mannami, Pedro Marques-Vidal, Jean Claude N. Mbanya, Norma McFarlane-Anderson, Roberto Miccoli, Juhani Miettola, Hoang V. Minh, Juan F. Miquel, J. Jaime Miranda, Mostafa K. Mohamed, V. Mohan, Salim Mohanna, Ali Mokdad, Willem F. Mollentze, Dante D. Morales, Karen Morgan, Lorenza M. Muiesan, Sergio Muntoni, Iraj Nabipour, Tomoko Nakagami, Vinay Nangia, Barbara Nemesure, Martin Neovius, Kjersti A. Nerhus, Flavio Nervi, Hannelore Neuhauser, Minh Nguyen, Toshiharu Ninomiya, Marianna Noale, Sang W. Oh, Takayoshi Ohkubo, Oliviero Olivieri, Ayse Emel Önal, Altan Onat, Myriam Oróstegui, Hermann Ouedraogo, Wen-Harn Pan, Demosthenes B. Panagiotakos, Francesco Panza, Yongsoo Park, Valeria M. A. Passos, Mangesh S. Pednekar, Marco A., Pistelli, Francesco, Pedro Plans, Maria Polakowska, Neil Poulter, Dorairaj Prabhakaran, Qing Qiao, Masoud Rafiei, Olli, T. Raitakari, Luiz R. Ramos, Sanjay Rampal, Lekhraj Rampal, Finn Rasmussen, Kanala K. R. Reddy, Josep Redon, Luis Revilla, Victoria Reyes-García, Ragab B. Roaeid, Fernando Rodriguez-Artalejo, Rosalba Rojas-Martinez, Kimmo Ronkainen, Luis Rosero-Bixby, Gregory A. Roth, Harshpal S. Sachdev, José R. Sánchez, Selim Y. Sanisoglu, Susana Sans, Nizal Sarraf-Zadegan, Marcia Scazufca, Beatriz D. Schaan, Norberto Schapochnik, Hedi Schelleman, Ione J. C. Schneider, C. Mary Schooling, Bernhard Schwarz, Cevad Sekuri, Martha S. Sereday, Lluís Serra-Majem, Jonathan Shaw, Abdul S. Shera, Zumin Shi, Rahman Shiri, Xiao Ou Shu, Diego Augusto Santos Silva, Eglé Silva, Leon A. Simons, Margaret Smith, Stefan Söderberg, Suharko Soebardi, Vincenzo Solfrizzi, Emily Sonestedt, Ahmet Soysal, Pär Stattin, Aryeh D. Stein, George S. Stergiou, Jochanan Stessman, Akihiro Sudo, Machi Suka, Valter Sundh, Kristina Sundquist, Johan Sundström, Andrew B. Swai, E. Shyong Tai, Kristian Tambs, Fikru Tesfaye, George N. Thomas, Margaret Thorogood, Reijo S. Tilvis, Martin Tobias, Liv E. Torheim, Peter Trenkwalder, Jaakko O. Tuomilehto, Josep A. Tur, Christophe Tzourio, Ana I. Uhernik, Flora A. Ukoli, Nigel Unwin, Stephen Vander Hoorn, Mark P. Vanderpump, Jose Javier Varo, Marit B. Veierød, Gustavo Velásquez-Meléndez, Monique Verschuren, Lucie Viet, Salvador Villalpando, Jesus Vioque, Peter Vollenweider, Stefano Volpato, Ningli Wang, Ya X. Wang, Mark Ward, Sarwono Waspadji, Lennart X. Welin, Lars Wilhelmsen, Johann Willeit, Mark Woodward, André J. Xavier, Fei Xu, Liang Xu, Akira Yamamoto, Gonghuan Yang, Xiaoguang Yang, Li-Chia Yeh, Jin-Sang Yoon, Qisheng You, Zhijie Yu, Jian Zhang, Lei Zhang, Wei Zheng, Maigeng Zhou.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3728::f6d67d21ee2e11538552e8e693280d59
http://hdl.handle.net/11568/1122009
http://hdl.handle.net/11568/1122009
Publikováno v:
Free Radical Biology and Medicine. 20:743-749
In animal models of gallstone disease inflammatory alterations of the gallbladder mucosa are regularly found before the first appearance of cholesterol monohydrate crystals in bile. At sites of inflammation granulocytes generate reactive oxygen metab
Autor:
Silvia, Zúñiga, Héctor, Molina, Lorena, Azocar, Ludwig, Amigo, Flavio, Nervi, Fernando, Pimentel, Nicolás, Jarufe, Marco, Arrese, Frank, Lammert, Juan F, Miquel
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 28(7)
Intestinal cholesterol absorption may influence gallstone formation and its modulation could be a useful therapeutic strategy for gallstone disease (GSD). Ezetimibe (EZET) is a cholesterol-lowering agent that specifically inhibits intestinal choleste