Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Juan F, Medrano"'
Autor:
Victoria Asselstine, Juan F. Medrano, Malane M. M. Muniz, Bonnie A. Mallard, Niel A. Karrow, Angela Cánovas
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Despite regulatory elements such as long non - coding RNAs representing most of the transcriptome, the functional understanding of long non - coding RNAs in relation to major health conditions including bovine mastitis is limited. This study
Externí odkaz:
https://doaj.org/article/cb2cbde2a20e4e1cb912086bc78958c2
Autor:
Luis A. Contreras-Méndez, Juan F. Medrano, Milton G. Thomas, R. Mark Enns, Scott E. Speidel, Guillermo Luna-Nevárez, Pedro A. López-Castro, Fernando Rivera-Acuña, Pablo Luna-Nevárez
Publikováno v:
Animals, Vol 14, Iss 2, p 213 (2024)
Anti-Müllerian hormone (AMH) is proposed as a biomarker for fertility in cattle, yet this associative relationship appears to be influenced by heat stress (HS). The objective was to test serum AMH and AMH-related single nucleotide polymorphisms (SNP
Externí odkaz:
https://doaj.org/article/39fbc92511b648b39c892bcce3dea2c1
Autor:
Ricardo Zamorano-Algandar, Juan F. Medrano, Milton G. Thomas, R. Mark Enns, Scott E. Speidel, Miguel A. Sánchez-Castro, Guillermo Luna-Nevárez, José C. Leyva-Corona, Pablo Luna-Nevárez
Publikováno v:
Biology, Vol 12, Iss 5, p 679 (2023)
Dairy production in Holstein cows in a semiarid environment is challenging due to heat stress. Under such conditions, genetic selection for heat tolerance appears to be a useful strategy. The objective was to validate molecular markers associated wit
Externí odkaz:
https://doaj.org/article/d5e52f99e3a845f4a1269b37704166cb
Autor:
Colin Kern, Ying Wang, Xiaoqin Xu, Zhangyuan Pan, Michelle Halstead, Ganrea Chanthavixay, Perot Saelao, Susan Waters, Ruidong Xiang, Amanda Chamberlain, Ian Korf, Mary E. Delany, Hans H. Cheng, Juan F. Medrano, Alison L. Van Eenennaam, Chris K. Tuggle, Catherine Ernst, Paul Flicek, Gerald Quon, Pablo Ross, Huaijun Zhou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
In order to interpret non-coding variants, information about regulatory elements in the genome is essential. Here, the authors annotate regulatory elements in chicken, pig and cattle, and characterize conservation of these elements between species.
Externí odkaz:
https://doaj.org/article/2a0d0f16ec8a4f52b116348aae893cf0
Autor:
Michelle M. Halstead, Colin Kern, Perot Saelao, Ying Wang, Ganrea Chanthavixay, Juan F. Medrano, Alison L. Van Eenennaam, Ian Korf, Christopher K. Tuggle, Catherine W. Ernst, Huaijun Zhou, Pablo J. Ross
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Although considerable progress has been made towards annotating the noncoding portion of the human and mouse genomes, regulatory elements in other species, such as livestock, remain poorly characterized. This lack of functional an
Externí odkaz:
https://doaj.org/article/021ea6b0f94e46c5a3998910d08cf005
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10218 (2022)
We investigated the possibility of single-step genome editing in small ruminants by CRISPR-Cas9 zygote electroporation. We targeted SOCS2 and PDX1 in sheep embryos and OTX2 in goat embryos, utilizing a dual sgRNA approach. Gene editing efficiency was
Externí odkaz:
https://doaj.org/article/05e8d08ff394404ab402f6cd54faf9d9
Autor:
Michelle M. Halstead, Alma Islas-Trejo, Daniel E. Goszczynski, Juan F. Medrano, Huaijun Zhou, Pablo J. Ross
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
A comprehensive annotation of transcript isoforms in domesticated species is lacking. Especially considering that transcriptome complexity and splicing patterns are not well-conserved between species, this presents a substantial obstacle to genomic s
Externí odkaz:
https://doaj.org/article/0d6121504286487dadedaae5da0946af
Autor:
Colin Kern, Ying Wang, James Chitwood, Ian Korf, Mary Delany, Hans Cheng, Juan F. Medrano, Alison L. Van Eenennaam, Catherine Ernst, Pablo Ross, Huaijun Zhou
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Numerous long non-coding RNAs (lncRNAs) have been identified and their roles in gene regulation in humans, mice, and other model organisms studied; however, far less research has been focused on lncRNAs in farm animal species. Whi
Externí odkaz:
https://doaj.org/article/23e9e760eb6c474f9711e87e26f60d37
Autor:
Anna Cuscó, Janelle M. Belanger, Liza Gershony, Alma Islas-Trejo, Kerinne Levy, Juan F. Medrano, Armand Sánchez, Anita M. Oberbauer, Olga Francino
Publikováno v:
Microbiome, Vol 5, Iss 1, Pp 1-15 (2017)
Abstract Background The individual, together with its environment, has been reported as the main force driving composition and structure of skin microbiota in healthy dogs. Therefore, one of the major concerns when analyzing canine skin microbiota is
Externí odkaz:
https://doaj.org/article/580beff8ed1c415da41126c26957ae6f
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 3, Pp 865-870 (2017)
Parameters of bone geometry such as width, length, and cross-sectional area are major determinants of bone strength. Although these traits are highly heritable, few genes influencing bone geometry have been identified. Here, we dissect a major quanti
Externí odkaz:
https://doaj.org/article/5dca533493c348918d4539fe1297b828