Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Juan E. Camacho Londoño"'
Publikováno v:
Cells, Vol 11, Iss 20, p 3225 (2022)
Calcium signalling in platelets through store operated Ca2+ entry (SOCE) or receptor-operated Ca2+ entry (ROCE) mechanisms is crucial for platelet activation and function. Orai1 proteins have been implicated in platelet’s SOCE. In this study we eva
Externí odkaz:
https://doaj.org/article/845834a39e764ddc84c4a6e7d64e4464
Autor:
Lucas Bacmeister, Sebastian Segin, Rebekka Medert, Diana Lindner, Marc Freichel, Juan E. Camacho Londoño
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Aim: Cardiac pressure-volume (PV loop) analysis under β-adrenergic stimulation is a powerful method to simultaneously determine intrinsic cardiac function and β-adrenergic reserve in mouse models. Despite its wide use, several key approaches of thi
Externí odkaz:
https://doaj.org/article/3754e18e862048b9ac03318e4ea2d8b0
Autor:
Sebastian Segin, Michael Berlin, Christin Richter, Rebekka Medert, Veit Flockerzi, Paul Worley, Marc Freichel, Juan E. Camacho Londoño
Publikováno v:
Cells, Vol 9, Iss 5, p 1092 (2020)
Pathological cardiac remodeling correlates with chronic neurohumoral stimulation and abnormal Ca2+ signaling in cardiomyocytes. Store-operated calcium entry (SOCE) has been described in adult and neonatal murine cardiomyocytes, and Orai1 proteins act
Externí odkaz:
https://doaj.org/article/2d2511f56f374360bc34d2e171854732
Autor:
Juan E. Camacho Londoño, André Marx, Axel E. Kraft, Alexander Schürger, Christin Richter, Alexander Dietrich, Peter Lipp, Lutz Birnbaumer, Marc Freichel
Publikováno v:
Cells, Vol 9, Iss 2, p 322 (2020)
TRPC proteins form cation conducting channels regulated by different stimuli and are regulators of the cellular calcium homeostasis. TRPC are expressed in cardiac cells including cardiac fibroblasts (CFs) and have been implicated in the development o
Externí odkaz:
https://doaj.org/article/29752007b159443c9aeec537c9250d02
Autor:
Juan E. Camacho Londoño, Peter Lipp, Norbert Hubner, Lutz Birnbaumer, Vladimir Kuryshev, Markus Zorn, Qinghai Tian, Peter P. Nawroth, Marc Freichel, Alexander Dietrich, Kathrin Saar, Christoph Dieterich
Publikováno v:
Progress in Biophysics and Molecular Biology. 159:86-104
Aims After summarizing current concepts for the role of TRPC cation channels in cardiac cells and in processes triggered by mechanical stimuli arising e.g. during pressure overload, we analysed the role of TRPC1 and TRPC4 for background Ca2+ entry (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebc06d6fdf5e4a0eb7a597900b6db6e6
https://doi.org/10.1016/j.pbiomolbio.2020.07.006
https://doi.org/10.1016/j.pbiomolbio.2020.07.006
Autor:
Ayse Sanlialp, Shirin Doroudgar, Leon Kiper, Frank Zimmermann, Agnieszka A. Gorska, Sascha Dlugosz, Hugo A. Katus, Mirko Völkers, Jana Burghaus, Eshita Varma, Dagmar Schumacher, Juan E. Camacho Londoño, Marc Freichel, Eva Riechert, Vivien Kmietczyk, Angela Wirth, Thanh Cao Ho, Christoph Hofmann
Publikováno v:
Journal of Molecular and Cellular Cardiology. 141:30-42
Pathological cardiac hypertrophy is an independent risk for heart failure (HF) and sudden death. Deciphering signaling pathways regulating intracellular Ca2+ homeostasis that control adaptive and pathological cardiac growth may enable identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c392b0788d106856889220a5a0006b1a
https://doi.org/10.1016/j.yjmcc.2020.03.004
https://doi.org/10.1016/j.yjmcc.2020.03.004
Autor:
Rebekka, Medert, Lucas, Bacmeister, Sebastian, Segin, Marc, Freichel, Juan E, Camacho Londoño
Publikováno v:
Journal of visualized experiments : JoVE. (171)
Determination of the cardiac function is a robust endpoint analysis in animal models of cardiovascular diseases in order to characterize effects of specific treatments on the heart. Due to the feasibility of genetic manipulations the mouse has become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::016e28646506960ad56d7eb95875d47e
https://pubmed.ncbi.nlm.nih.gov/34096910
https://pubmed.ncbi.nlm.nih.gov/34096910
Publikováno v:
Journal of Visualized Experiments.
Determination of the cardiac function is a robust endpoint analysis in animal models of cardiovascular diseases in order to characterize effects of specific treatments on the heart. Due to the feasibility of genetic manipulations the mouse has become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7426398f1095bd1a2df19fe7ba4826
https://doi.org/10.3791/62057-v
https://doi.org/10.3791/62057-v
Autor:
Michael Berlin, Marc Freichel, Paul F. Worley, Juan E. Camacho Londoño, Sebastian Segin, Rebekka Medert Veit Flockerzi, Christin Richter
Publikováno v:
Cells
Cells, Vol 9, Iss 1092, p 1092 (2020)
Volume 9
Issue 5
Cells, Vol 9, Iss 1092, p 1092 (2020)
Volume 9
Issue 5
Pathological cardiac remodeling correlates with chronic neurohumoral stimulation and abnormal Ca2+ signaling in cardiomyocytes. Store-operated calcium entry (SOCE) has been described in adult and neonatal murine cardiomyocytes, and Orai1 proteins act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1118298dcb00716f1015f4366b273fd7
Genetic background influences expression and function of the cation channel TRPM4 in the mouse heart
Autor:
Lucas Bacmeister, Rebekka Medert, Sebastian Segin, Andy Pironet, Juan E. Camacho Londoño, Rudi Vennekens, Marc Freichel
Publikováno v:
Basic Research in Cardiology
Transient receptor potential melastatin 4 (TRPM4) cation channels act in cardiomyocytes as a negative modulator of the L-type Ca2+ current. Ubiquitous Trpm4 deletion in mice leads to an increased β-adrenergic inotropy in healthy mice as well as afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5241a018bf490fcc9bbc7ca84fbdfe08
https://doi.org/10.1007/s00395-020-00831-x
https://doi.org/10.1007/s00395-020-00831-x