Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Juan E. Belforte"'
Publikováno v:
J Neurosci
How do animals adopt a given behavioral strategy to solve a recurrent problem when several effective strategies are available to reach the goal? Here we provide evidence that striatal cholinergic interneurons (SCINs) modulate their activity when mice
Autor:
Ettel Keifman, Camila Coll, Cecilia Tubert, Rodrigo M. Paz, Juan E. Belforte, Mario G. Murer, Barbara Y. Braz
Publikováno v:
J Neurosci
In Parkinson's disease patients and rodent models, dopaminergic neuron loss (DAN) results in severe motor disabilities. In contrast, general motility is preserved after early postnatal DAN loss in rodents. Here we used mice of both sexes to show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e928ef6fb91553e7e7592eb77d3b88
https://europepmc.org/articles/PMC9698699/
https://europepmc.org/articles/PMC9698699/
Publikováno v:
J Neurosci
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Although the etiology of schizophrenia is still unknown, it is accepted to be a neurodevelopmental disorder that results from the interaction of genetic vulnerabilities and environmental insults. Although schizophrenia’s pathophysiology is still un
Publikováno v:
Schizophr Bull
Altered Excitatory/Inhibitory (E/I) balance of cortical synaptic inputs has been proposed as a central pathophysiological factor for psychiatric neurodevelopmental disorders, including schizophrenia (SZ). However, direct measurement of E/I synaptic b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1076d88718add68aed1ef5c8ba5c35ba
https://europepmc.org/articles/PMC8379555/
https://europepmc.org/articles/PMC8379555/
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62978 (2013)
The marked anatomical and functional changes taking place in the medial prefrontal cortex (PFC) during adolescence set grounds for the high incidence of neuropsychiatric disorders with adolescent onset. Although circuit refinement through synapse pru
Externí odkaz:
https://doaj.org/article/f169afe2d0ef4290aa2c1a705992bf05
Autor:
Carlos Alfredo Pretell Annan, Noelia Belen Diaz, Juan E. Belforte, Kenji Hashimoto, Yuko Fujita, Kazuhito Nakao, Sunny Zhihong Jiang, Kazu Nakazawa, Vivek Jeevakumar, Karen L. Eskow Jaunarajs
Publikováno v:
Schizophrenia Bulletin
Amphetamine-induced augmentation of striatal dopamine and its blunted release in prefrontal cortex (PFC) is a hallmark of schizophrenia pathophysiology. Although N-methyl-D-aspartate receptor (NMDAR) hypofunction is also implicated in schizophrenia,
Autor:
Mariela Veronica Escande, Juan E. Belforte, Rosario Moratalla, Gimena Gomez, Mario Gustavo Murer, Lorena Rela, Oscar S. Gershanik, Irene Rita Eloisa Taravini, Luz M. Suárez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Using bacterial artificial chromosome¿double transgenic mice expressing tdTomato in D1 receptor-medium spiny neurons (MSNs) and enhanced green fluorescent protein in D2 receptor-MSNs, we have studied changes in spine density and perisomatic GABAergi
Autor:
Sonia Espindola, Jean-Marc Gallo, Juan E. Ferrario, Ana Damianich, Juan E. Belforte, Maria Elena Avale, Manuela Sartor, Rodrigo Javier Alvarez
Publikováno v:
Espíndola, S L, Damianich, A, Alvarez, R J, Sartor, M, Belforte, J E, Ferrario, J E, Gallo, J-M & Avale, M E 2018, ' Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy ', Cell Reports, vol. 23, no. 3, pp. 709-715 . https://doi.org/10.1016/j.celrep.2018.03.079
Cell Reports, Vol 23, Iss 3, Pp 709-715 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Cell Reports, Vol 23, Iss 3, Pp 709-715 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The microtubule-associated protein tau regulates myriad neuronal functions, such as microtubule dynamics, axonal transport and neurite outgrowth. Tauopathies are neurodegenerative disorders characterized by the abnormal metabolism of tau, which accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a0dbce0308c51c0aeb258585fda120
https://www.sciencedirect.com/science/article/pii/S2211124718304406
https://www.sciencedirect.com/science/article/pii/S2211124718304406
Autor:
Maria Elena Avale, Juan E. Belforte, Manuela Sartor, Ana Damianich, Jean-Marc Gallo, Sonia Espindola
Publikováno v:
Alzheimer's & Dementia. 13
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repetitive stimulation of cognitive forebrain circuits at frequencies capable of inducing corticostriatal long term plasticity is increasingly being used with therapeutic purposes in patients with neuropsychiatric disorders. However, corticostriatal