Respiratory syncytial virus infection in adults: Differences with influenza

Autor: Oscar Losa-Martin, Alicia Frisuelos-Garcia, Alberto Delgado-Iribarren, Maria Rosa Martin-deCabo, Oriol Martin-Segarra, Ana Vegas-Serrano, Rafael Hervas-Gomez, Leonor Moreno-Nuñez, Maria Velasco-Arribas, Juan E. Losa-Garcia

Publikováno v: Enfermedades infecciosas y microbiologia clinica (English ed.).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8887f7111b77477a3a5cf0478d6b1153
https://doi.org/10.1016/j.eimce.2022.12.013

Social and health factors associated with adverse treatment outcomes among people with multidrug-resistant tuberculosis in Sierra Leone: a national, retrospective cohort study

Autor: Rashidatu Fouad Kamara, Matthew J Saunders, Foday Sahr, Juan E Losa-Garcia, Lynda Foray, Geraint Davies, Tom Wingfield

Publikováno v: The Lancet. Global health. 10(4)

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is a global health emergency. We aimed to evaluate treatment outcomes among people with MDR-TB in Sierra Leone and investigate social and health factors associated with adverse treatment outcomes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03e443a31f34190cff3d642261fa04c
https://pubmed.ncbi.nlm.nih.gov/35303445

First confirmation of importation and transmission in Spain of the newly identified SARS-CoV-2 B.1.1.7 variant

Autor: Elena Rodriguez Baena, M Dolores Folgueira, Irene Muñoz Gallego, María Ordobás Gavín, Arturo Fraile Torres, Esther Viedma, Isabel Fradejas-Villajos, M Angeles Meléndez, Pilar Catalán, Juan E. Losa-Garcia, Cristina Andrés Zayas, Darío García de Viedma, Carmen Del Arco, Daniel López-Wolf, Sergio Buenestado-Serrano, Raúl Recio, Carolina Campelo-Gutierrez, Víctor Manuel de la Cueva, Araceli Arce Arnáez, Andres Von Wermitz, Laura Cardeñoso, Sara González Bodi, Patricia Muñoz, Higinio Iglesias-Franco, Jennifer Villa, M José Goyanes, Rafael Delgado, Laura Pérez-Lago, Pedro J Sola Campoy

Publikováno v: Enfermedades Infecciosas Y Microbiologia Clinica

INTRODUCTION: A newly identified SARS-CoV-2 variant, VOC202012/01 originating lineage B.1.1.7, recently emerged in the United Kingdom. The rapid spread in the UK of this new variant has caused other countries to be vigilant. MATERIAL AND METHODS: We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16087b96777e21d01b9b4a30d8aa54b8
https://pubmed.ncbi.nlm.nih.gov/33685741

Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2): week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials

Autor: Pedro Cahn, Juan Sierra Madero, José Ramón Arribas, Andrea Antinori, Roberto Ortiz, Amanda E Clarke, Chien-Ching Hung, Jürgen K Rockstroh, Pierre-Marie Girard, Jörg Sievers, Choy Man, Alexander Currie, Mark Underwood, Allan R Tenorio, Keith Pappa, Brian Wynne, Anna Fettiplace, Martin Gartland, Michael Aboud, Kimberly Smith, Lidia Cassetti, Daniel David, Laura Figueras, Marcelo Losso, Gustavo Lopardo, Sergio Lupo, Norma Porteiro, Marisa Sánchez, Mark Bloch, David Cooper, Robert Finlayson, Anthony Kelleher, Kenneth Koh, David Lewis, James McMahon, Richard Moore, Norman Roth, Matthew Shields, Stephane De Wit, Eric Florence, Jean-Christophe Goffard, Remy Demeester, Patrick Lacor, Bernard Vandercam, Linos Vandekerckhove, Jonathan Angel, Jean-Guy Baril, Brian Conway, Alexandra De Pokomandy, Jason Szabo, Sharon Walmsley, Olivier Bouchaud, Christian Chidiac, Pierre Delobel, Cecile Goujard, Christine Katlama, Jean-Michel Molina, Gilles Pialoux, Patrick Philibert, Johannes Bogner, Stefan Esser, Ivanka Krznaric, Clara Lehmann, Christoph Spinner, Hans-Jurgen Stellbrink, Christoph Stephan, Albrecht Stoehr, Enrico Barchi, Pietro Caramello, Francesco Castelli, Anna Maria Cattelan, Antonella D'Arminio Monforte, Antonio Di Biagio, Giovanni Di Perri, Andrea Gori, Franco Maggiolo, Barbara Menzaghi, Guglielmo Migliorino, Cristina Mussini, Giovanni Penco, Massimo Puoti, Giuliano Rizzardini, Roberto Gulminetti, Adriano Lazzarin, Tiziano Quirino, Laura Sighinolfi, Pierluigi Viale, Gerardo Amaya Tapia, Jaime Andrade Villanueva, Enrique R Granados Reyes, Alma Perez Rios, Mario Santoscoy Gomez, Jan Den Hollander, Bart Rijnders, José A Hidalgo, Luis Hercilla Vasquez, Luis Illescas, Anita Olczak, Kamal Mansinho, Patricia Paula Correia Pacheco, Eugénio Teófilo, Jose Saraiva da Cunha, Rui Sarmento e Castro, Rosário Serrão, Manuela Arbune, Cristian Jianu, Anca Oprea, Liliana Preotescu, Liviu-Jany Prisacariu, Elena Belonosova, Olga Borodkina, Oxana Chernova, Natalia Gankina, Svetlana Kizhlo, Valeriy Kulagin, Nadezhda Kurina, Firaya Nagimova, Vadim Pokrovsky, Elena Ryamova, Evgeny Voronin, Alexey Yakovlev, Richard Kaplan, Sun Hee Lee, Shin-Woo Kim, Sang-Il Kim, Woo Joo Kim, Antonio Antela Lopez, Jose L Casado Osorio, Manuel A Castaño Carracedo, Ignacio De Los Santos Gil, Vicente Estrada Perez, Vicenç Falco Ferrer, Luis Force, Maria Jose Galinda Puerto, Miguel Garcia Deltoro, Josep M Gatell, Miguel A Goenaga Sanchez, Ana González Cordón, Hernando Knobel, Juan Carlos Lopez Bernaldo de Quiros, Juan E Losa Garcia, Mar Masia, Marta Montero-Alsonso, Antonio Ocampo Hermida, Juan Pasquau Liaño, Joaquin Portilla Sogorb, Federico Pulido Ortega, Antonio Rivera Roman, Jose Ramon Santos Fernandez, Rafael Torres Perea, Jesus Troya Garcia, Pompeyo Viciana Fernandez, Alexandra Calmy, Christoph Hauser, Jan Fehr, Shu-Hsing Cheng, Wen-Chien Ko, Hsi-Hsun Lin, Po-Liang Lu, Yu-Ting Tseng, Ning-Chi Wang, Wing-Wai Wong, Chia-Jui Yang, Roberto Arduino, Paul Benson, Mezgebe Berhe, Fritz Bredeek, Cynthia Brinson, Thomas Campbell, Gordon Crofoot, Douglas Cunningham, Edwin DeJesus, Robin Dretler, Joseph Eron, Kenneth Fife, Carl Fichtenbaum, Jason Flamm, Deborah Goldstein, Samir Gupta, Debbie Hagins, Margaret Hoffman-Terry, Dushyantha Jayaweera, Clifford Kinder, Daniel Klein, Cheryl McDonald, Anthony Mills, Ronald Nahass, Olayemi Osiyemi, Edgar Overton, David Parks, David Prelutsky, Moti Ramgopal, Shannon Schrader, Beverly Sha, Gary Simon, James Sims, Daniel Skiest, Jihad Slim, Karen Tashima, Blair Thedinger, Brian Gazzard, Julie Fox, Margaret Johnson, Stephen Kegg, Saye Khoo, Charles Mazhude, Chloe Orkin, Gabriel Schembri, Andrew Ustianowski

Publikováno v: The Lancet, 393(10167), 143-155. Elsevier Ltd.

Summary Background Effective two-drug regimens could decrease long-term drug exposure and toxicity with HIV-1 antiretroviral therapy (ART). We therefore aimed to evaluate the efficacy and safety of a two-drug regimen compared with a three-drug regime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad70b60db548619c808fac0879d6106
https://hdl.handle.net/11380/1221490

Cyclosporin A decreases human macrophage interleukin-6 synthesis at post-transcriptional level

Autor: Ana M. Rodríguez López, Juan E. Losa Garcia, Antonio Jiménez López, Jesús Pérez Losada, Rogelio González Sarmiento, José Luis Pérez Arellano, María Rosa Martín de Cabo, Fernando Mateos Rodríguez

Publikováno v: Mediators of Inflammation
Mediators of Inflammation, Vol 8, Iss 4-5, Pp 253-259 (1999)

In addition to its well-established effect on T cells, cyclosporin A (CsA) also inhibits inflammatory cytokine production by macrophages. However, little is known about the mechanism of action of CsA on macrophage cytokine production. We measured the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f5714af37266f9fa1b4361fb025d34
http://europepmc.org/articles/PMC1781800