Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Juan Codina"'
Autor:
Zachary B. Powell, Thomas D. DuBose, Raymond B. Penn, Juan Codina, Cristina M. Furdui, Snezana Petrovic, Timothy S. Opyd
Publikováno v:
American Journal of Physiology-Renal Physiology. 301:F536-F543
The H+-K+-ATPase α-subunit (HKα2) participates importantly in systemic acid-base homeostasis and defends against metabolic acidosis. We have previously shown that HKα2plasma membrane expression is regulated by PKA (Codina J, Liu J, Bleyer AJ, Penn
Autor:
Juan Codina, Thomas D. DuBose
Publikováno v:
Seminars in Nephrology. 26:345-351
Two H(+), K(+)-adenosine triphosphatase (ATPase) proteins participate in K(+) absorption and H(+) secretion in the renal medulla. Both the gastric (HKalpha(1)) and colonic (HKalpha(2)) H(+),K(+)-ATPases have been localized and characterized by a numb
Autor:
Elizabeth Petroske, Jian Li, Mike J. Werle, Thomas D. DuBose, Mark C. Willingham, Juan Codina
Publikováno v:
Kidney International. 66(3):1068-1075
The effect of β-subunit assembly on function and localization of the colonic H + ,K + -ATPase α-subunit. Background Previous experiments from our laboratory have demonstrated that HKα 2 coimmunoprecipitated with β 1 -Na + ,K + -ATPase. Although H
Publikováno v:
Kidney International. 55:2376-2382
Peptides derived from the human transferrin receptor stimulate endosomal acidification via a G i -type protein. Background Acidification of the endosomal compartment is a prerequisite for intracellular processing of endocytosed complexes. Endosomal a
The α-Subunit of the Colonic H+,K+-ATPase Assembles with β1-Na+,K+-ATPase in Kidney and Distal Colon
Publikováno v:
Journal of Biological Chemistry. 273:7894-7899
Previous experiments from our laboratory (Codina, J., Kone, B. C., Delmas-Mata, J. T., and DuBose, T. D., Jr. (1996) J. Biol. Chem. 271, 29759-29763) demonstrated that the alpha-subunit of the colonic H+, K+-ATPase (HKalpha2) requires coexpression wi
Publikováno v:
Journal of Biological Chemistry. 271:29759-29763
The functional and pharmacological properties of the alpha-subunit of the colonic H+,K+-ATPase (alphaC) were studied in Xenopus laevis oocytes. alphaC was injected with different rat beta-subunits, the beta-subunit of the gastric H+,K+-ATPase (betaG,
Publikováno v:
American journal of physiology. Renal physiology. 303(9)
Acid-secreting intercalated cells respond to changes in systemic pH through regulation of apical H+transporters. Little is known about the mechanism by which these cells sense changes in extracellular pH (pHo). Pyk2 is a nonreceptor tyrosine kinase a
Autor:
Deepak A. Deshpande, Thomas C. Rich, Sarah Horvat, Juan Codina, Raymond B. Penn, Wenkuan Xin, Huandong Yan, Thomas D. DuBose, Reynold A. Panettieri
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(9)
A-kinase anchoring proteins (AKAPs) have emerged as important regulatory molecules that can compartmentalize cAMP signaling transduced by β2-adrenergic receptors (β2ARs); such compartmentalization ensures speed and fidelity of cAMP signaling and ef
Autor:
Enrico Stefani, Juan Codina, L. Toro, F M Strickland, A M Spiegel, Atsuko Yatani, T Sawada, S C Froehner, Susan L. Hamilton, M. J. Hawkes
Publikováno v:
Journal of Biological Chemistry. 266:19528-19535
The alpha subunits of heterotrimeric GTP-binding (G) proteins act upon ion channels through both cytoplasmic and membrane-delimited pathways (Brown, A. M., and Birnbaumer, L. (1990) Annu. Rev. Physiol. 52, 197-213). The membrane pathway may involve e
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 72:867-875
We and others have used the term MVP dysautonomia for a particular subset of hyperadrenergic dysautonomia patients. The role of the stimulatory guanine nucleotide regulatory protein (Gs) in this dysautonomia was studied by cholate extraction of Gs fr