Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Juan Carlos Pena-Philippides"'
Autor:
Juan Carlos Pena‐Philippides, Amy Sabrina Gardiner, Ernesto Caballero‐Garrido, Rong Pan, Yiliang Zhu, Tamara Roitbak
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 13 (2018)
Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to ce
Externí odkaz:
https://doaj.org/article/4198973b22b3475c8ac73ba80928a1d3
Autor:
Tamara Roitbak, Juan Carlos Pena-Philippides, Rong Pan, Amy S. Gardiner, Yiliang Zhu, Ernesto Caballero-Garrido
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Brain microvascular endothelial cells form a highly selective blood brain barrier regulated by the endothelial tight junctions. Cerebral ischemia selectively targets tight junction protein complexes, which leads to significant damage to ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c316d14f0b65d24d2710c585d12703f5
https://doi.org/10.1161/jaha.118.009244
https://doi.org/10.1161/jaha.118.009244
Autor:
Erik B. Erhardt, Tamar Lordkipanidze, Juan Carlos Pena-Philippides, Yirong Yang, Tamara Roitbak, Denis E. Bragin, Ernesto Caballero-Garrido
Publikováno v:
Journal of Neuroscience. 35:12446-12464
A multifunctional microRNA, miR-155, has been recently recognized as an important modulator of numerous biological processes. In our previous in vitro studies, miR-155 was identified as a potential regulator of the endothelial morphogenesis. The pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc974e86c9514ff17780787849102c3c
https://doi.org/10.1523/jneurosci.1641-15.2015
https://doi.org/10.1523/jneurosci.1641-15.2015
Autor:
Erik B. Erhardt, Juan Carlos Pena-Philippides, Tamara Roitbak, Z. Galochkina, Ernesto Caballero-Garrido
Evaluation of functional outcome is widely used across species to assess the recovery process following various pathological conditions, including spinal cord injury, musculo-skeletal injury, mithochondrial disease, neuropathic cancer, Huntington's d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46fc03fd8012234f9bdedeabc3a5125
https://europepmc.org/articles/PMC5543803/
https://europepmc.org/articles/PMC5543803/
Publikováno v:
Journal of Neuroinflammation
Background MicroRNA miR-155 is implicated in modulation of the inflammatory processes in various pathological conditions. In our previous studies, we demonstrated that in vivo inhibition of miR-155 promotes functional recovery after mouse experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262352442e58e43512f4ef2150e92aba
https://doi.org/10.1186/s12974-016-0753-x
https://doi.org/10.1186/s12974-016-0753-x
Autor:
Neerad C. Mishra, Sravanthi Gundavarapu, Juan Carlos Pena-Philippides, Shashi P. Singh, Mohan L. Sopori, Jules Rir-sima-ah, Raymond J. Langley, Seddigheh Razani-Boroujerdi
Publikováno v:
Journal of Neuroimmune Pharmacology. 6:585-596
Although a number of inflammatory cytokines are increased during sepsis, the clinical trials aimed at down-regulating these mediators have not improved the outcome. These paradoxical results are attributed to loss of the “tolerance” phase that no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::704210dc804865b5af1a642da6908137
https://doi.org/10.1007/s11481-011-9284-5
https://doi.org/10.1007/s11481-011-9284-5
Autor:
Raymond J. Langley, Seddigheh Razani-Boroujerdi, Juan Carlos Pena-Philippides, Neerad C. Mishra, Mohan L. Sopori, Shashi P. Singh
Publikováno v:
Toxicology Letters. 167:231-237
Annually, approximately two million babies are exposed to cigarette smoke in utero and postnatally through cigarette smoking of their mothers. Exposure to mainstream cigarette smoke is known to impair both innate and adaptive immunities, and it has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b61b53b38fbbfddf9798587d421efa
https://doi.org/10.1016/j.toxlet.2006.10.001
https://doi.org/10.1016/j.toxlet.2006.10.001
Immunosuppressive and Anti-Inflammatory Effects of Nicotine Administered by Patch in an Animal Model
Autor:
Mohan L. Sopori, Roma Kalra, Raymond J. Langley, Juan Carlos Pena-Philippides, Shashi P. Singh, Seddigheh Razani-Boroujerdi
Publikováno v:
Clinical and Vaccine Immunology. 11:563-568
To study the immunological effects of nicotine, there are several rodent models for chronic nicotine administration. These models include subcutaneously implanted miniosmotic pumps, nicotine-spiked drinking water, and self-administration via jugular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ebc09a177cc304a3530be6a4325cec
https://doi.org/10.1128/cdli.11.3.563-568.2004
https://doi.org/10.1128/cdli.11.3.563-568.2004
Autor:
Juan Carlos Pena-Philippides, Sean Hagberg, Edwin M. Nemoto, Yirong Yang, Tamara Roitbak, Olga Bragina
Publikováno v:
Translational stroke research. 5(4)
Pulsed electromagnetic fields (PEMF) have been demonstrated to have anti-inflammatory and pro-regenerative effects in animals and humans. We used the FDA-approved Sofpulse™ (Ivivi Health Sciences, LLC) to study effect of PEMF on infarct size and po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b88a169422f82f053070508cfb5f2c1
https://pubmed.ncbi.nlm.nih.gov/24549571
https://pubmed.ncbi.nlm.nih.gov/24549571
Autor:
Juan Carlos Pena-Philippides, Raymond J. Langley, Shashi P. Singh, JeanClare Seagrave, Neerad C. Mishra, Mohan L. Sopori, Brandon J. Rice
Publikováno v:
Journal of toxicology and environmental health. Part A. 74(19)
Silicosis, a fibrotic granulomatous lung disease, may occur through accidental high-dose or occupational inhalation of silica, leading to acute/accelerated and chronic silicosis, respectively. While chronic silicosis has a long asymptomatic latency,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e405739c435ba75458bbfc702e3a6f65
https://pubmed.ncbi.nlm.nih.gov/21830856
https://pubmed.ncbi.nlm.nih.gov/21830856