Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Juan Carlos G. Marvizón"'
cAMP signaling through protein kinase A and Epac2 induces substance P release in the rat spinal cord
Publikováno v:
Neuropharmacology
Using neurokinin 1 receptor (NK1R) internalization to measure of substance P release in rat spinal cord slices, we found that it was induced by the adenylyl cyclase (AC) activator forskolin, by the protein kinase A (PKA) activators 6-Bnz-cAMP and 8-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc676b40a353114ef32edd6145eb71c
https://pubmed.ncbi.nlm.nih.gov/33744339
https://pubmed.ncbi.nlm.nih.gov/33744339
Autor:
Wenling Chen, Juan Carlos G. Marvizón
Latent sensitization is a model of chronic pain in which a persistent state of pain hypersensitivity is suppressed by opioid receptors, as evidenced by the ability of opioid antagonists to induce a period of mechanical allodynia. Our objective was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4197abf46fc98e0dbd8c503dfed995
Autor:
Wenling Chen, Juan Carlos G. Marvizón
Publikováno v:
Brain research. 1746
Latent sensitization is a long-term model of chronic pain in which hyperalgesia is continuously suppressed by opioid receptors, as demonstrated by the induction of mechanical allodynia by opioid antagonists. Different intracellular signals may mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca089be134146deaa670ba8cb61b61d6
https://pubmed.ncbi.nlm.nih.gov/32579948
https://pubmed.ncbi.nlm.nih.gov/32579948
Autor:
Juan Carlos G. Marvizón, Wenling Chen
Latent sensitization is a long-term model of chronic pain in which hyperalgesia is continuously suppressed by opioid receptors. This is demonstrated by the induction of mechanical allodynia by opioid antagonists. Different intracellular signals may m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e549a88ba11df6d0bd06bdde475298
Autor:
Claire Gaveriaux-Ruff, Brigitte L. Kieffer, Amie L. Severino, Juan Carlos G. Marvizón, Wendy Walwyn, Wenling Chen, Joshua K. Hakimian
Publikováno v:
Pain. 159:1607-1620
The latent sensitization model of chronic pain reveals that recovery from some types of long-term hyperalgesia is an altered state in which nociceptive sensitization persists but is suppressed by the ongoing activity of analgesic receptors such as μ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a41b3a387f6398cedc1a4a4718c342
https://doi.org/10.1097/j.pain.0000000000001247
https://doi.org/10.1097/j.pain.0000000000001247
Publikováno v:
Neuropharmacology. 128:255-268
The interaction between NMDA receptors and μ-opioid receptors in primary afferent terminals was studied by using NMDA to induce substance P release, measured as neurokinin 1 receptor internalization. In rat spinal cord slices, the μ-opioid receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73369bbe1f9d039882fab387aa1194a
https://doi.org/10.1016/j.neuropharm.2017.10.014
https://doi.org/10.1016/j.neuropharm.2017.10.014
Autor:
Helena S. Ennes, Wendy Walwyn, James A. McRoberts, Wenling Chen, Juan Carlos G. Marvizón, Ani Minasyan, Hyeyoung Kim
Publikováno v:
The Journal of Neuroscience. 36:204-221
Many chronic pain disorders alternate between bouts of pain and periods of remission. The latent sensitization model reproduces this in rodents by showing that the apparent recovery (“remission”) from inflammatory or neuropathic pain can be rever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11d969f63acbdfdc6e8cc2530b53c9df
https://doi.org/10.1523/jneurosci.1751-15.2016
https://doi.org/10.1523/jneurosci.1751-15.2016
Autor:
Juan Carlos G. Marvizón, Wenling Chen
Publikováno v:
Neuropharmacology. 177:108253
Latent sensitization is a model of chronic pain in which a persistent state of pain hypersensitivity is suppressed by opioid receptors, as evidenced by the ability of opioid antagonists to induce a period of mechanical allodynia. Our objective was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408f1f65e999c1247ac094984c97990c
https://doi.org/10.1016/j.neuropharm.2020.108253
https://doi.org/10.1016/j.neuropharm.2020.108253
Publikováno v:
Neuroscience. 267:67-82
Opiate analgesia in the spinal cord is impaired during neuropathic pain. We hypothesized that this is caused by a decrease in μ-opioid receptor inhibition of neurotransmitter release from primary afferents. To investigate this possibility, we measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e1edc97e29d6a675651e83b3aade50
https://doi.org/10.1016/j.neuroscience.2014.02.023
https://doi.org/10.1016/j.neuroscience.2014.02.023
Publikováno v:
European Journal of Neuroscience. 32:963-973
GABA(B) , μ-opioid and adrenergic α(2) receptors inhibit substance P release from primary afferent terminals in the dorsal horn. Studies in cell expression systems suggest that μ-opioid and GABA(B) receptors inhibit transmitter release from primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3691c5eb88c2826bc64726a30909f539
https://doi.org/10.1111/j.1460-9568.2010.07335.x
https://doi.org/10.1111/j.1460-9568.2010.07335.x