Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Juan Carabana"'
Publikováno v:
The Journal of Immunology. 186:3556-3562
In CD4−CD8− double-negative thymocytes, the murine Tcrb locus is composed of alternating blocks of active and inactive chromatin containing Tcrb gene segments and trypsinogen genes, respectively. Although chromatin structure is appreciated to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49dd3177772a3e241768731d8ae609c2
https://doi.org/10.4049/jimmunol.1003164
https://doi.org/10.4049/jimmunol.1003164
Publikováno v:
The Journal of Immunology. 183:6513-6521
CD69 is a type II C-type lectin involved in lymphocyte migration and cytokine secretion. CD69 expression represents one of the earliest available indicators of leukocyte activation and its rapid induction occurs through transcriptional activation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0c8ec46be2b6a1539cd591eb183a94d
https://doi.org/10.4049/jimmunol.0900839
https://doi.org/10.4049/jimmunol.0900839
Publikováno v:
Immunological Reviews. 200:224-232
V(D)J recombination proceeds according to defined developmental programs at T-cell receptor (TCR) and immunoglobulin loci as a function of cell lineage and stage of differentiation. Although the molecular details are still lacking, such regulation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9ae387eb009d7794e808baefe2aece
https://doi.org/10.1111/j.0105-2896.2004.00155.x
https://doi.org/10.1111/j.0105-2896.2004.00155.x
Publikováno v:
Immunology. 104:11-18
Although situated close together within the T-cell receptor (TCR) alpha/delta locus, TCR delta and TCR alpha gene segments are controlled by two developmental stage-specific enhancers and are activated according to distinct developmental programmes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ebc8da01ea91b3a59aed070536ebf47
https://doi.org/10.1046/j.1365-2567.2001.01304.x
https://doi.org/10.1046/j.1365-2567.2001.01304.x
Publikováno v:
Immunity. 24:361-363
In this issue of Immunity, Oestreich et al. (2006) show that, during V(D)J recombination, RSSs may have distinct accessibility requirements. Some rely on an enhancer-intrinsic, general chromatin opening function, whereas others require enhancer-promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeed490189b5ce0094595743bd3b1ba
https://doi.org/10.1016/j.immuni.2006.04.002
https://doi.org/10.1016/j.immuni.2006.04.002
Autor:
David L. Wiest, Roberta E. Parrott, Jeffery H. Carpenter, Marcella Sarzotti, Michael S. Krangel, Myriah Cooney, Chan M. Win, Jens Peter Holst Lauritsen, Juan Carabana, Xiao-Ping Zhong, E.O. Sajaroff, Michael D. Keller, Joseph L. Roberts, Rebecca H. Buckley
Publikováno v:
Blood. 109(8)
CD3zeta is a subunit of the T-cell antigen receptor (TCR) complex required for its assembly and surface expression that also plays an important role in TCR-mediated signal transduction. We report here a patient with T(-)B(+)NK(+) severe combined immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a2449431c09d51b973bf3d2433e1b9
https://pubmed.ncbi.nlm.nih.gov/17170122
https://pubmed.ncbi.nlm.nih.gov/17170122
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 174(7)
Accessibility control of V(D)J recombination at Ag receptor loci depends on the coordinate activities of transcriptional enhancers and germline promoters. Recombination of murine Tcrd gene segments is known to be regulated, at least in part, by the T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f2e36bfd23a4754a4d8d22af2f549c
https://pubmed.ncbi.nlm.nih.gov/15778374
https://pubmed.ncbi.nlm.nih.gov/15778374
Autor:
Juan Carabana, Michael S. Krangel, Cristina Hernández-Munain, Michelle Taylor McMurry, Xiao-Ping Zhong
Publikováno v:
Immunologic research. 22(2-3)
The joining of T cell receptor (TCR) and immunoglobulin (Ig) gene segments through the process of V(D)J recombination occurs in a lineage-specific and developmental-stage-specific way during the early stages of lymphocyte development. Such developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf8bb9dc033b9010b3b7512473ff215
https://pubmed.ncbi.nlm.nih.gov/11339350
https://pubmed.ncbi.nlm.nih.gov/11339350
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(21)
Previous studies have identified nuclear matrix attachment regions (MARs) that are closely associated with transcriptional enhancers in the IgH, Igκ, and T cell receptor (TCR) β loci, but have yielded conflicting information regarding their functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c322120d98e84b161c9c2850bc04c7a2
https://pubmed.ncbi.nlm.nih.gov/10518560
https://pubmed.ncbi.nlm.nih.gov/10518560