Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Juan C. de la Torre"'
Autor:
Fernando M. Quintana, Juan C. de la Torre, Guillermo Barcena-Gonzalez, María P. Guerrero-Lebrero, Elisa Guerrero
Publikováno v:
SoftwareX, Vol 26, Iss , Pp 101696- (2024)
NESIM-RT is a specialized tool designed for simulating neuromorphic systems. In this new release we extend its capabilities to include state-of-the art models like the AdexLIF and Izhikevich, and to incorporate dynamic synaptic mechanisms such as Spi
Externí odkaz:
https://doaj.org/article/b887ed3f032c45e6aa23501793e3a1a6
Autor:
Haydar Witwit, Carlos Alberto Betancourt, Beatrice Cubitt, Roaa Khafaji, Heinrich Kowalski, Nathaniel Jackson, Chengjin Ye, Luis Martinez-Sobrido, Juan C. de la Torre
Publikováno v:
Viruses, Vol 16, Iss 9, p 1362 (2024)
The mammarenavirus matrix Z protein plays critical roles in virus assembly and cell egress. Meanwhile, heterotrimer complexes of a stable signal peptide (SSP) together with glycoprotein subunits GP1 and GP2, generated via co-and post-translational pr
Externí odkaz:
https://doaj.org/article/3cc8055eadb04d62a0b2a4c713f1089e
Publikováno v:
Viruses, Vol 13, Iss 7, p 1187 (2021)
Mammarenaviruses are prevalent pathogens distributed worldwide, and several strains cause severe cases of human infections with high morbidity and significant mortality. Currently, there is no FDA-approved antiviral drugs and vaccines against mammare
Externí odkaz:
https://doaj.org/article/32542867eec948f186f5dc4e1283e0bd
Autor:
James E. Robinson, Kathryn M. Hastie, Robert W. Cross, Rachael E. Yenni, Deborah H. Elliott, Julie A. Rouelle, Chandrika B. Kannadka, Ashley A. Smira, Courtney E. Garry, Benjamin T. Bradley, Haini Yu, Jeffrey G. Shaffer, Matt L. Boisen, Jessica N. Hartnett, Michelle A. Zandonatti, Megan M. Rowland, Megan L. Heinrich, Luis Martínez-Sobrido, Benson Cheng, Juan C. de la Torre, Kristian G. Andersen, Augustine Goba, Mambu Momoh, Mohamed Fullah, Michael Gbakie, Lansana Kanneh, Veronica J. Koroma, Richard Fonnie, Simbirie C. Jalloh, Brima Kargbo, Mohamed A. Vandi, Momoh Gbetuwa, Odia Ikponmwosa, Danny A. Asogun, Peter O. Okokhere, Onikepe A. Follarin, John S. Schieffelin, Kelly R. Pitts, Joan B. Geisbert, Peter C. Kulakoski, Russell B. Wilson, Christian T. Happi, Pardis C. Sabeti, Sahr M. Gevao, S. Humarr Khan, Donald S. Grant, Thomas W. Geisbert, Erica Ollmann Saphire, Luis M. Branco, Robert F. Garry
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Lassa virus can cause haemorrhagic fever for which no specific treatment currently exists. Here the authors have cloned 113 monoclonal antibodies from the survivors of Lassa infection and show that the majority of neutralizing antibodies target a com
Externí odkaz:
https://doaj.org/article/d40aae7302c442638a735c72e28f07c6
Autor:
Yu-Jin Kim, Beatrice Cubitt, Yingyun Cai, Jens H. Kuhn, Daniel Vitt, Hella Kohlhof, Juan C. de la Torre
Publikováno v:
Viruses, Vol 12, Iss 8, p 821 (2020)
Mammarenaviruses cause chronic infections in rodents, which are their predominant natural hosts. Human infection with some of these viruses causes high-consequence disease, posing significant issues in public health. Currently, no FDA-licensed mammar
Externí odkaz:
https://doaj.org/article/22a4df7bf5db418482a939e8c482b137
Autor:
Yíngyún Caì, Masaharu Iwasaki, Brett F. Beitzel, Shuīqìng Yú, Elena N. Postnikova, Beatrice Cubitt, Lisa Evans DeWald, Sheli R. Radoshitzky, Laura Bollinger, Peter B. Jahrling, Gustavo F. Palacios, Juan C. de la Torre, Jens H. Kuhn
Publikováno v:
Viruses, Vol 10, Iss 11, p 655 (2018)
Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000⁻300,000 individuals yearly in western Africa and frequently causes lethal disease. Currently, no LASV-specific antivirals or vaccines are commercially available for prevention or tr
Externí odkaz:
https://doaj.org/article/cff65530011244159414a272e7224567
Publikováno v:
Viruses, Vol 4, Iss 10, Pp 2137-2161 (2012)
Arenaviruses merit significant interest because several family members are etiological agents of severe hemorrhagic fevers, representing a major burden to public health. Currently, there are no FDA-licensed vaccines against arenaviruses and the only
Externí odkaz:
https://doaj.org/article/76cce75a9fa04792a30e5dd3609b9492
Publikováno v:
Journal of Virology. 97
Host-directed antivirals have gained great interest as an antiviral strategy to counteract the rapid emergence of drug-resistant viruses. The chaperonin TRiC/CCT complex has been involved in the life cycle of several viruses, including dengue, Zika,
Publikováno v:
J Virol
Several mammarenaviruses cause severe hemorrhagic fever (HF) disease in humans and pose important public health problems in their regions of endemicity. There are no United States (US) Food and Drug Administration (FDA)-approved mammarenavirus vaccin
Publikováno v:
Current topics in microbiology and immunology. 439
Members of the family Arenaviridae are classified into four genera: Antennavirus, Hartmanivirus, Mammarenavirus, and Reptarenavirus. Reptarenaviruses and hartmaniviruses infect (captive) snakes and have been shown to cause boid inclusion body disease