Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Juan C. Salinas"'
Autor:
Marcela Alcota, Juan C. Salinas, Marco Cornejo-Ovalle, Pilar Ruiz de Gauna, Fermín E. González
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The University should be considered a favourable space and agent for the training and transmission of values and attitudes related to professionalism, such as responsibility, teamwork and ethical commitment. In addition, dentistry
Externí odkaz:
https://doaj.org/article/74ace7ae733f4b39b94c9685e92018ed
Autor:
Tamilselvan Rajasekaran, Graeme C. Freestone, Rodrigo Galindo-Murillo, Barbara Lugato, Lorena Rico, Juan C. Salinas, Hans Gaus, Michael T. Migawa, Eric E. Swayze, Thomas E. Cheatham, Stephen Hanessian, Punit P. Seth
Publikováno v:
J Am Chem Soc
Journal of the American Chemical Society, vol 144, iss 4
Journal of the American Chemical Society, vol 144, iss 4
The binding affinity of therapeutic oligonucleotides (ONs) for their cognate RNA is determined by the rates of association (ka) and dissociation (kd). Single-stranded ONs are highly flexible and can adopt multiple conformations in solution, some of w
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 39:384-406
We report the synthesis and biophysical evaluation of an azabicycle dinucleotide with restricted γ, β, and ε torsion angles, featuring the introduction of a piperidine ring that locks the conformation of the nucleoside into an RNA-type nucleic aci
Autor:
Juan C. Salinas, Stephen Hanessian, Robert D. Giacometti, Punit P. Seth, Michael E. Østergaard, Eric E. Swayze
Publikováno v:
Organic & Biomolecular Chemistry. 14:2034-2040
The design, synthesis and biophysical evaluation of two highly-constrained tricyclic analogues of locked nucleic acid (LNA), which restrict rotation around the C4'-C5'-exocyclic bond (torsion angle γ) and enhance hydrophobicity in the minor groove a
Publikováno v:
Organic letters. 20(17)
The stereocontrolled synthesis of a novel oxabicyclic nucleoside phosphonate comprising a perhydrofuropyran core unit was achieved. It was incorporated in an oligonucleotide sequence as a 5'-3' phosphonate-phosphate insert, and the stability properti
Publikováno v:
The Journal of Organic Chemistry. 79:11651-11660
Approaches to the synthesis of the constrained 5-methyluracil nucleoside (S)-cEt-BNA, a key "gapmer" unit in a number of biologically relevant antisense oligonucleotides, are described using 5-methyluridine as starting material. In the shorter synthe
Autor:
José M. Moya, Juan C. Salinas Hilburg, José Luis Risco Martín, Jose Luis Rodrigo, Marina Zapater
Publikováno v:
CISIS
Ninth International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS 2015) | Ninth International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS 2015) | 08/07/2015-10/07/2015 | Blumenau, Brasil
Archivo Digital UPM
instname
Ninth International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS 2015) | Ninth International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS 2015) | 08/07/2015-10/07/2015 | Blumenau, Brasil
Archivo Digital UPM
instname
The increasing demand for computational resources has led to a significant growth of data center facilities. A major concern has appeared regarding energy efficiency and consumption in servers and data centers. The use of flexible and scalable server
Publikováno v:
Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
Instituto de Salud Carlos III (ISCIII)
Academica-e: Repositorio Institucional de la Universidad Pública de Navarra
Universidad Pública de Navarra
Noise Mapping, Vol 1, Iss 1 (2014)
Instituto de Salud Carlos III (ISCIII)
Academica-e: Repositorio Institucional de la Universidad Pública de Navarra
Universidad Pública de Navarra
Noise Mapping, Vol 1, Iss 1 (2014)
Two of the main objectives of the European Directive on environmental noise are, firstly, to unify acoustic indices for assessing environmental noise and, secondly, to standardize assessment methodologies. The ultimate goal is to objectively and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a50f194e08af43ddb90c93be476f974
https://hdl.handle.net/2454/38052
https://hdl.handle.net/2454/38052
Publikováno v:
Marine Mammal Science. 10:471-473
Using Grammatical Evolution Techniques to Model the Dynamic Power Consumption of Enterprise Servers.
Autor:
Hilburg, Juan C. Salinas, Zapater, Marina, Martin, Jose L. Risco, Moya, Jose M., Rodrigo, Jose L.
Publikováno v:
2015 Ninth International Conference on Complex, Intelligent & Software Intensive Systems; 2015, p110-117, 8p