Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Juan C. Piña"'
Autor:
Wenlong Zhang, Huaqing Chen, Liuyan Ding, Jie Huang, Mengran Zhang, Yan Liu, Runfang Ma, Shaohui Zheng, Junwei Gong, Juan C. Piña‐Crespo, Yunlong Zhang
Publikováno v:
Exploration, Vol 3, Iss 3, Pp n/a-n/a (2023)
Abstract Contactin‐associated protein‐like 4 (Cntnap4) is critical for GABAergic transmission in the brain. Impaired Cntnap4 function is implicated in neurological disorders, such as autism; however, the role of Cntnap4 on memory processing is po
Externí odkaz:
https://doaj.org/article/455e5addb6bb436c9dd620117d03a645
Publikováno v:
Brain Plasticity
Background: Acute (ex vivo) and chronic (in vivo) alcohol exposure induces neuroplastic changes in the dorsal striatum, a critical region implicated in instrumental learning. Objective: Sex differences are evident in alcohol reward and reinforcement,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d5f8c533f79fee4af7c096ba6d4fa4
http://europepmc.org/articles/PMC7903017
http://europepmc.org/articles/PMC7903017
Autor:
Wulfran Trenet, Nancy Xing, Britta D. Sibley, Sucharita S. Somkuwar, Sumaiya Olia, Alison D. Kreisler, Juan C. Piña-Crespo, Jacob R Watson, Chitra D. Mandyam, Yosef Avchalumov, Tejash Bharadwaj, Marisa Roberto, Amin A Shayan
Publikováno v:
Neuropsychopharmacology
Angiogenesis or proliferation of endothelial cells plays a role in brain microenvironment homeostasis. Previously we have shown enhanced expression of markers of angiogenesis in the medial prefrontal cortex during abstinence in an animal model of eth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664e7a5aa60c2f14fee02da8afc75e20
https://europepmc.org/articles/PMC8429630/
https://europepmc.org/articles/PMC8429630/
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-11 (2019)
Molecular Brain
Molecular Brain
Alzheimer’s disease (AD) is an aging-related neurological disorder characterized by synaptic loss and dementia. Wnt/β-catenin signaling is an essential signal transduction pathway that regulates numerous cellular processes including cell survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c36f3cc2932d61ba1fe826d23dc147e
https://doaj.org/article/6550cea85bf24f87b175d5c864ef8368
https://doaj.org/article/6550cea85bf24f87b175d5c864ef8368
Autor:
Don W. Cleveland, Lu-Lin Jiang, Tongfei Liu, Wenxi Xu, Lisa Zhou, Huaxi Xu, Tao Long, Sandrine Da Cruz, María Jesús Delgado Rodríguez, Yingjun Zhao, Dongxian Zhang, Xiaoguang Li, Juan C. Piña-Crespo, Timothy Y. Huang, John Ravits, Bing Zhu, Haiyang Yu
Publikováno v:
Journal of Clinical Investigation. 129:3103-3120
Mechanisms underlying motor neuron degeneration in amyotrophic lateral sclerosis (ALS) are yet unclear. Specific deletion of the ER-component membralin in astrocytes manifested postnatal motor defects and lethality in mice, causing the accumulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c52e2b644cdba2e7459a8f8cb8a3d6a
https://doi.org/10.1172/jci127695
https://doi.org/10.1172/jci127695
Autor:
Juan Valderrama, Carlos Alberto Vega-Mejía, Jaén Suárez-Rodríguez, Melissa Correa, Valentina Blanco, Laura Malagón-Alvarado, Juan C. Piña, Mariana Lopera, Laura De La Rosa
Publikováno v:
Production Research ISBN: 9783030763060
Course Timetabling at universities can be defined as the scheduling of different courses in specific time slots. To carry out this process it is necessary to take into account key factors such as: available courses, the distribution of time slots and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e7c4380786415d047d4b2df41c4123
https://doi.org/10.1007/978-3-030-76307-7_3
https://doi.org/10.1007/978-3-030-76307-7_3
Autor:
Swagata Ghatak, Maria Talantova, Sara Sanz-Blasco, Mohd Waseem Akhtar, Jeffery W. Kelly, Stuart A. Lipton, William P. Lynch, Dorit Trudler, Juan C. Piña-Crespo, Karthik Bodhinathan, Yvonne S. Eisele
Publikováno v:
J Neurosci
Synaptic and neuronal loss are major neuropathological characteristics of Parkinson's disease. Misfolded protein aggregates in the form of Lewy bodies, comprised mainly of α-synuclein (αSyn), are associated with disease progression, and have also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d04f7556e99abdc9d37a9b1cbb4a39
https://pubmed.ncbi.nlm.nih.gov/33483428
https://pubmed.ncbi.nlm.nih.gov/33483428
Autor:
Brian P. Head, Wulfran Trenet, Yosef Avchalumov, Alison D. Kreisler, Juan C. Piña-Crespo, Chitra D. Mandyam, Mahasweta Nayak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8219, p 8219 (2021)
International journal of molecular sciences, vol 22, iss 15
International Journal of Molecular Sciences
Volume 22
Issue 15
International journal of molecular sciences, vol 22, iss 15
International Journal of Molecular Sciences
Volume 22
Issue 15
Dopamine D1 receptor (D1R) function is regulated by membrane/lipid raft-resident protein caveolin-1 (Cav1). We examined whether altered expression of Cav1 in the dorsal striatum would affect self-administration of methamphetamine, an indirect agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7b8b59bdfda88fffbd0a2d041a39ae
https://doi.org/10.3390/ijms22158219
https://doi.org/10.3390/ijms22158219
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 24, Pp 2978-2990 (2017)
Chinese Medical Journal
Chinese Medical Journal
Objective: To review recent research advances on tau, a major player in Alzheimer’s disease (AD) pathogenesis, a biomarker for AD onset, and potential target for AD therapy. Data Sources: This review was based on a comprehensive search using online
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2543e891b44a832a80edfc9eb607dfa2
https://doi.org/10.4103/0366-6999.220313
https://doi.org/10.4103/0366-6999.220313
Autor:
Thomas E. Willnow, Timothy Y. Huang, Eliezer Masliah, Yan Liu, Xiaoguang Li, Juan C. Piña-Crespo, Huaxi Xu, Yingjun Zhao, Bing Zhu, Elena B. Pasquale, Yu Sun, Lu-Lin Jiang
Publikováno v:
The Journal of Experimental Medicine
Huang et al. show that the Alzheimer’s disease (AD) risk factor SORLA inhibits amyloid β–induced synaptotoxicity and cognitive impairment through interacting with and subsequently inactivating EphA4. These findings provide a novel mechanism by w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cbbcea54f1d6c4d2a01e09608c3648
https://doi.org/10.1084/jem.20171413
https://doi.org/10.1084/jem.20171413