Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Juan C. Mayo"'
Autor:
Alejandro Alvarez-Artime, Belen Garcia-Soler, Pedro Gonzalez-Menendez, Sheila Fernandez-Vega, Rafael Cernuda-Cernuda, David Hevia, Juan C. Mayo, Rosa M. Sainz
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Adipose tissue has gained attention due to its potential paracrine role. Periprostatic adipose tissue surrounds the prostate and the prostatic urethra, and it is an essential player in prostate cancer progression. Since obesity is
Externí odkaz:
https://doaj.org/article/d8b21b4158a14cab9e1ce16f0da4a391
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2717 (2023)
Nowadays, the study of cell metabolism is a hot topic in cancer research. Many studies have used 2D conventional cell cultures for their simplicity and the facility to infer mechanisms. However, the limitations of bidimensional cell cultures to recre
Externí odkaz:
https://doaj.org/article/2f309e101ce445fa93e9a6e69edfe4b0
Autor:
Isabel Quiros-Gonzalez, Pedro Gonzalez-Menendez, Juan C. Mayo, David Hevia, Francisco Artime-Naveda, Sheila Fernandez-Vega, Mario Fernandez-Fernandez, Pablo Rodriguez-Gonzalez, José I. Garcia-Alonso, Rosa M. Sainz
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 313 (2022)
Prostate cancer is the second leading cause of cancer in men across the globe. The prostate gland accounts for some unique glycolytic metabolic characteristics, which causes the metabolic features of prostate tumor initiation and progression to remai
Externí odkaz:
https://doaj.org/article/682345f4ae014cc89147e7c1f6866505
Autor:
Pedro Gonzalez-Menendez, David Hevia, Rebeca Alonso-Arias, Alejandro Alvarez-Artime, Aida Rodriguez-Garcia, Sandrina Kinet, Ivan Gonzalez-Pola, Naomi Taylor, Juan C. Mayo, Rosa M. Sainz
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 112-127 (2018)
Glucose, chief metabolic support for cancer cell survival and growth, is mainly imported into cells by facilitated glucose transporters (GLUTs). The increase in glucose uptake along with tumor progression is due to an increment of facilitative glucos
Externí odkaz:
https://doaj.org/article/c84b028c5123400eb74d3a8c79501889
Autor:
Aida Rodriguez-Garcia, David Hevia, Juan C. Mayo, Pedro Gonzalez-Menendez, Lucia Coppo, Jun Lu, Arne Holmgren, Rosa M. Sainz
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 634-647 (2017)
Accumulating evidence suggests that natural bioactive compounds, alone or in combination with traditional chemotherapeutic agents, could be used as potential therapies to fight cancer. In this study, we employed four natural bioactive compounds (curc
Externí odkaz:
https://doaj.org/article/b0e40129d39446a9bcbbc8944e54f153
Autor:
Juan C. Mayo, Rosa M. Sainz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3645 (2020)
During the last 25 years we have accomplished great advances in melatonin research, regarding antioxidant or anti-inflammatory functions, oncostatic actions, glucose metabolism regulation or plant physiology, among others. Of course, we should not fo
Externí odkaz:
https://doaj.org/article/90368a3efa854145adfbfc6dafcb48ce
Publikováno v:
Antioxidants, Vol 9, Iss 2, p 142 (2020)
Diets are currently characterized by elevated sugar intake, mainly due to the increased consumption of processed sweetened foods and drinks during the last 40 years. Diet is the main source of advanced glycation endproducts (AGEs). These are toxic co
Externí odkaz:
https://doaj.org/article/e7426cb3af2f47029d8f6876cc8577ea
Autor:
Alejandro Alvarez-Artime, Rafael Cernuda-Cernuda, Francisco-Artime-Naveda, Vanesa Cepas, Pedro Gonzalez-Menendez, Sheila Fernadez-Vega, Isabel Quiros-Gonzalez, Rosa M. Sainz, Juan C. Mayo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 548 (2020)
Neuroindole melatonin, a hormone synthesized during the night mainly—but not exclusively—by the pineal gland of all vertebrates, functions as an adapting signal to the light-dark cycle. Its antioxidant, neuroprotective, anti-inflammatory, and ant
Externí odkaz:
https://doaj.org/article/82a12318030b4cbda7eb63bf72ca6a84
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T lymphocytes, from their first encounter with their specific antigen as naïve cell until the last stages of their differentiation, in a replicative state of senescence, go through a series of phases. In several of these stages, T lymphocytes are su
Externí odkaz:
https://doaj.org/article/d01fbbb6da7c4eb1aeb188bb34f0a904
Autor:
Juan C. Mayo, Arturo Aguado, Rafael Cernuda-Cernuda, Alejandro Álvarez-Artime, Vanesa Cepas, Isabel Quirós-González, David Hevia, Rosa M. Sáinz
Publikováno v:
Molecules, Vol 23, Iss 8, p 1999 (2018)
Melatonin, N-acetyl-5-methoxytryptamine, is an indole mainly synthesized from tryptophan in the pineal gland and secreted exclusively during the night in all the animals reported to date. While the pineal gland is the major source responsible for thi
Externí odkaz:
https://doaj.org/article/81e0534b276d409d94c67d7ae0e64cad