Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Juan C. Laguna"'
Autor:
Roger Bentanachs, Lluïsa Miró, Rosa M. Sánchez, Patricia Ramírez-Carrasco, Concepció Amat, Marta Alegret, Anna Pérez, Núria Roglans, Juan C. Laguna
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117067- (2024)
Background and aims: Drugs resolving steatotic liver disease (SLD) could prevent the evolution of metabolic dysfunction associated SLD (MASLD) to more aggressive forms but must show not only efficacy, but also a high safety profile. Repurposing of dr
Externí odkaz:
https://doaj.org/article/5df01807c6744dbc8f567596638bf3f0
Autor:
Núria Roglans, Elena Fauste, Roger Bentanachs, Ana M. Velázquez, Madelin Pérez-Armas, Cristina Donis, María I. Panadero, Marta Alegret, Paola Otero, Carlos Bocos, Juan C. Laguna
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 473 (2022)
We previously demonstrated that treatment with BemA (bempedoic acid), an inhibitor of ATP citrate lyase, significantly reduces fatty liver in a model of liver steatosis (HFHFr—female Sprague-Dawley rat fed a high-fat high-fructose diet). Since the
Externí odkaz:
https://doaj.org/article/099727e40dd74b5b81636f3371b79327
Autor:
Silvia Rodrigo, María I. Panadero, Elena Fauste, Lourdes Rodríguez, Núria Roglans, Juan J. Álvarez-Millán, Paola Otero, Juan C. Laguna, Carlos Bocos
Publikováno v:
Nutrients, Vol 11, Iss 8, p 1935 (2019)
Endoplasmic reticulum (ER) homeostasis is crucial to appropriate cell functioning, and when disturbed, a safeguard system called unfolded protein response (UPR) is activated. Fructose consumption modifies ER homeostasis and has been related to metabo
Externí odkaz:
https://doaj.org/article/abb7d31bca58486abb1a0b8e75894d39
Autor:
Gemma Llaverias, Manuel Vázquez-Carrera, Rosa M. Sánchez, Véronique Noé, Carlos J. Ciudad, Juan C. Laguna, Marta Alegret
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 11, Pp 2015-2024 (2004)
Peroxisome proliferator-activated receptor γ (PPARγ) activation or overexpression induces caveolin-1 (cav-1) expression in several cell types. The objective of this study was to investigate if PPAR agonists could also regulate the cav-1 gene in mac
Externí odkaz:
https://doaj.org/article/2d424694008f45528f41eed9f6ec29f2
Autor:
Mireia Jové, Joel Salla, Anna Planavila, Àgatha Cabrero, Liliane Michalik, Walter Wahli, Juan C. Laguna, Manuel Vázquez-Carrera
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 1, Pp 113-123 (2004)
Type 2 diabetes has been related to a decrease of mitochondrial DNA (mtDNA) content. In this study, we show increased expression of the peroxisome proliferator-activated receptor-α (PPARα) and its target genes involved in fatty acid metabolism in s
Externí odkaz:
https://doaj.org/article/b78e7176f6594d0ca2d32637ba580906
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 2, Pp 388-398 (2003)
Activation of nuclear factor-κB (NF-κB) is required for hypertrophic growth of cardiomyocytes. Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase I (CPT-I) that activates peroxisome proliferator-activated receptor α (PPARα) a
Externí odkaz:
https://doaj.org/article/181a12dee86c43af82fe64d310209ae0
Autor:
Sonia Muñoz, Manuel Merlos, Daniel Zambón, Cristina Rodríguez, Joan Sabaté, Emilio Ros, Juan C. Laguna
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 12, Pp 2069-2076 (2001)
In a randomized, cross-over feeding trial involving 10 men with polygenic hypercholesterolemia, a control, Mediterranean-type cholesterol-lowering diet, and a diet of similar composition in which walnuts replaced ~35% of energy from unsaturated fat,
Externí odkaz:
https://doaj.org/article/35abee197d5649f4b6487e3f1d352d54
Autor:
Miguel A. Muñoz, Ángel M. Alonso-Gómez, Olga Castañer, Marta Alegret, Miquel Fiol, Judith B. Ramírez-Sabio, José Lapetra, Ana Sánchez-Tainta, José J. Portu, José V. Sorlí, Montserrat Cofán, Xavier Pintó, Enrique Gómez-Gracia, Ramon Estruch, Jordi Salas-Salvadó, Miguel Ángel Martínez-González, Lluis Serra-Majem, Juan C. Laguna, Andrés Díaz-López, Montserrat Fitó, Emilio Ros
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
[EN]Objective: To examine associations between intake of simple sugars and cancer incidence, cancer mor-tality, and total mortality in a prospective cohort study based on the PREDIMED trial conducted from 2003 to 2010. Methods: Participants were olde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab398dec75a81fcdd24389735870d0af
http://hdl.handle.net/10810/54153
http://hdl.handle.net/10810/54153
Autor:
Marta Alegret, Ana Magdalena Velázquez, Gemma Sangüesa, Núria Roglans, Mercè Pallàs, Christian Griñán-Ferré, Juan C. Laguna, Miguel Baena, Rosa M. Sánchez
Publikováno v:
Food & Nutrition Research, Vol 65, Pp 1-15 (2021)
Dipòsit Digital de la UB
Universidad de Barcelona
Food & Nutrition Research
Dipòsit Digital de la UB
Universidad de Barcelona
Food & Nutrition Research
Background: Non-alcoholic fatty liver disease (NAFLD) has increased over the last decades and may evolve into hepatocellular carcinoma (HCC). As HCC is challenging to treat, knowledge on the modifiable risk factors for NAFLD/HCC (e.g. hyper caloric d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda95fa9834d422f88acff486db3df7f
https://doi.org/10.29219/fnr.v65.7670
https://doi.org/10.29219/fnr.v65.7670
Publikováno v:
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 19(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97392a00772e77ec5b36db9d07b5ef7d
https://pubmed.ncbi.nlm.nih.gov/33890396
https://pubmed.ncbi.nlm.nih.gov/33890396