Immune Cell Plasticity Allows for Resetting of Phenotype From Effector to Regulator With Combined Inhibition of Notch/eIF5A Pathways

Autor: Shahnawaz Imam, Pervaiz Dar, Saba Wasim Aziz, Zeeshan A. Zahid, Haider Sarwar, Tamanna Karim, Sarah Faisal, Ibrahim Haseeb, Ahmed S. Naqvi, Rayyan Shah, Amna Haque, Nancy Salim, Juan C. Jaume

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Type 1 diabetes (T1D) results from the destruction of pancreatic β-cells caused by an altered immune balance in the pancreatic microenvironment. In humans as well as in mouse models, T cells are well recognized as key orchestrators of T1D, which is

Externí odkaz: https://doaj.org/article/11f41157c227412190e76c9525833c80

Posttransplant Tacrolimus-Induced Diabetic Ketoacidosis: Review of the Literature

Autor: Zaid Ammari, Stella C. Pak, Mohammed Ruzieh, Osama Dasa, Abhinav Tiwari, Juan C. Jaume, Maria A. Alfonso-Jaume

Publikováno v: Case Reports in Endocrinology, Vol 2018 (2018)

Diabetic ketoacidosis (DKA) in patients receiving tacrolimus as part of their immunosuppressive regimen is a rarely reported adverse event. We report a patient with autosomal dominant polycystic kidney disease (ADPKD) and no known history of diabetes

Externí odkaz: https://doaj.org/article/5aa2a2dff83f447597ff89ae8b6b90a4

Hyperinsulinemia Associated Depression

Autor: Haider Sarwar, Shafiya Imtiaz Rafiqi, Showkat Ahmad, Sruthi Jinna, Sawleha Arshi Khan, Tamanna Karim, Omar Qureshi, Zeeshan A Zahid, Jon D Elhai, Jason C Levine, Shazia J Naqvi, Juan C Jaume, Shahnawaz Imam

Publikováno v: Clinical medicine insights. Endocrinology and diabetes. 15

Hyperinsulinemia promotes fat accumulation, causing obesity. Being an inflammatory state, obesity can induce further inflammation and is a risk factor for HPA (hypothalamic pituitary axis) dysregulation through hypercortisolism-related hyperglycemia.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8310bc9e3b388b743b3813b261de127b
https://pubmed.ncbi.nlm.nih.gov/35494421

Contributors

Autor: James L. Abbruzzese, Ghassan K. Abou-Alfa, Janet L. Abrahm, Jeffrey S. Abrams, Dara L. Aisner, Shaheen Alanee, Steven R. Alberts, Michelle Alonso-Basanta, Megan E. Anderson, Emmanuel S. Antonarakis, Frederick R. Appelbaum, Jonathan B. Ashman, Juliet L. Aylward, Ali A. Baaj, Arjun V. Balar, Lodovico Balducci, Nancy L. Bartlett, Qaiser Bashir, Lynda Kwon Beaupin, Al B. Benson, Ross Stuart Berkowitz, Donald A. Berry, Therese B. Bevers, John F. Boggess, Leif-Erik Bohman, Michael J. Borowitz, Jeff Boyd, Julie R. Brahmer, Joanna M. Brell, Karen Brown, Powel H. Brown, Paul A. Bunn, John C. Byrd, Dario Campana, David P. Carbone, H. Ballentine Carter, Jorge J. Castillo, Manpreet K. Chadha, Richard Champlin, Alfred E. Chang, Stephen J. Chanock, Vikash P. Chauhan, Herbert Chen, Ronald C. Chen, Nai-Kong V. Cheung, Michaele C. Christian, Paul M. Cinciripini, Michael F. Clarke, Anthony J. Cmelak, Robert E. Coleman, Jerry M. Collins, Kevin R. Coombes, Jorge Cortes, Mauro W. Costa, Anne Covey, Kenneth H. Cowan, Daniel J. Culkin, Brian G. Czito, Piero Dalerba, Josep Dalmau, Michael D'Angelica, Nancy E. Davidson, Theodore L. DeWeese, Mark Dickson, Maximilian Diehn, Subba R. Digumarthy, Angela Dispenzieri, Susan M. Domchek, Jeffrey S. Dome, John H. Donohue, James H. Doroshow, Jay F. Dorsey, Laura Doyon, Ronny Drapkin, Dan G. Duda, Linda R. Duska, Rosana Eisenberg, Mario A. Eisenberger, Janine Erler, Lola A. Fashoyin-Aje, Eric R. Fearon, Leslie A. Fecher, Joseph M. Flynn, James M. Ford, Patrick M. Forde, Arlene A. Forastiere, Laura P. Forsythe, Kelley V. Foyil, Wilbur A. Franklin, Alison G. Freifeld, Terence W. Friedlander, Debra L. Friedman, Arlan F. Fuller, Lorenzo Galluzzi, Tara C. Gangadhar, Marileila Varella Garcia, Mark C. Gebhardt, Amato J. Giaccia, Mark R. Gilbert, David Gius, John Glaspy, Ziya L. Gokaslan, Donald Peter Goldstein, Anne Kathryn Goodman, Karyn A. Goodman, Adrian Greenstein, Alexander Greenstein, Ellen R. Gritz, Thomas G. Gross, Stuart A. Grossman, Roy M. Gulick, Leonard L. Gunderson, Barrett G. Haik, John D. Hainsworth, Benjamin E. Haithcock, Christopher L. Hallemeier, Aphrothiti J. Hanrahan, Ernest T. Hawk, Jonathan E. Heinlen, Lee J. Helman, Joseph M. Herman, H. William Higgins, Alan L. Ho, Ingunn Holen, Andrew B. Hollander, Leora Horn, Scott C. Howard, Fumito Ito, Gopa Iyer, Elaine S. Jaffe, Elizabeth M. Jaffee, Rakesh K. Jain, William Jarnagin, Dawn E. Jaroszewski, Aminah Jatoi, Juan C. Jaume, Anuja Jhingran, David H. Johnson, Brian Johnston, Patrick G. Johnston, Lee W. Jones, Kevin D. Judy, Lisa A. Kachnic, Deborah Y. Kamin, Hagop Kantarjian, Giorgos Karakousis, Maher Karam-Hage, Zeynel A. Karcioglu, Norbert Kased, Michael B. Kastan, Stuart Katz, Eric Kauffman, Daniel R. Kaul, Ronan Kelly, Nancy Kemeny, Thomas W. Kensler, Erin E. Kent, Oliver Kepp, Joshua E. Kilgore, Ellen Kim, Katherine N. Kimmelshue, Lawrence Kleinberg, Boris Kobrinsky, Guido Kroemer, Shivaani Kummar, Daniel A. Laheru, Paul F. Lambert, Janessa Laskin, Mark Lawler, Jack Lee, John Y.K. Lee, Kachiu Lee, Nancy Y. Lee, Susanna I. Lee, Renato Lenzi, Allen S. Lichter, Allan Lipton, Charles L. Loprinzi, Paula Loughlin, Maeve Lowery, Sam J. Lubner, Emmy Ludwig, Robert A. Lustig, Mitchell Machtay, Lukasz Macyszyn, David M. Mahvi, Amit Maity, Robert G. Maki, Marcos Malumbres, John C. Mansour, Pierre P. Massion, Karen Colbert Maresso, Lauren A. Mauro, R. Samuel Mayer, Haggi Mazeh, Beryl McCormick, Charles J. McDonald, Steven Meranze, Chris J. Miller, Matthew I. Milowsky, Bruce Minsky, Margaret Mooney, Mark Morgan, A. Ross Morton, Anthony J. Murgo, Lida Nabati, William G. Nelson, Suzanne Nesbit, John E. Niederhuber, Ariela Noy, Tracey O'Connor, Kenneth Offit, Mihaela Onciu, Eileen M. O'Reilly, Elaine A. Ostrander, Joel Palefsky, Lisa Pappas-Taffer, Drew Pardoll, Jae H. Park, Peter C. Phillips, Roberto Pili, Peter A. Pinto, Miriam D. Post, Amy A. Pruitt, Ching-Hon Pui, Joe Bill Putnam, Christiane Querfeld, Martin N. Raber, Vance Rabius, Soroush Rais-Bahrami, S. Vincent Rajkumar, R. Lor Randall, Erinn B. Rankin, Nadeem Riaz, R. Taylor Ripley, Tina Rizack, Clifford G. Robinson, Jason D. Robinson, Leslie Robinson-Bostom, Carlos Rodriguez-Galindo, Ronald Rodriguez, Paul B. Romesser, Mark J. Roschewski, Steven T. Rosen, Myrna R. Rosenfeld, Nadia Rosenthal, Julia H. Rowland, James L. Rubenstein, Paul G. Rubinstein, Valerie W. Rusch, Anthony H. Russell, Charles J. Ryan, Virgilio Sacchini, Manuel Salto-Tellez, John T. Sandlund, Victor M. Santana, David F. Schneider, Kasmintan A. Schrader, Eric C. Schreiber, Lynn M. Schuchter, Daniel M. Sciubba, Michael V. Seiden, Ravi Sharaf, Neelesh Sharma, Karen L. Sherman, Jinru Shia, Kostandinos Sideras, Elin R. Sigurdson, Eric J. Small, Angela Smith, Penny K. Sneed, Stephen N. Snow, David B. Solit, James L. Speyer, Vladimir Spiegelman, Dempsey S. Springfield, Sheri L. Spunt, David P. Steensma, Elizabeth Stier, Thomas E. Stinchcombe, Richard M. Stone, Steven Kent Stranne, Michael B. Streiff, Paul T. Strickland, Bill Sugden, Martin S. Tallman, James E. Talmadge, Ayalew Tefferi, Joyce M.C. Teng, Joel E. Tepper, Kensei Tobinai, Joseph E. Tomaszewski, Frank Torti, Donald L. Trump, Kunihiro Tsukasaki, Sandra Van Schaeybroeck, Erin Vanness, Gauri R. Varadhachary, James Vardiman, Robert Vonderheide, Richard L. Wahl, Jean S. Wang, Toshiki Watanabe, Irving L. Weissman, Jeffrey D. White, Richard Wilson, Wyndham H. Wilson, Antonio C. Wolff, Richard J. Wong, Gary S. Wood, George Xu, Yaohui Gloria Xu, Stephen Yang, John Yee, Shlomit Yust-Katz, Timothy M. Zagar, Amer M. Zeidan, Elaine M. Zeman, Longzhen Zhang, Haoyi Zheng, James A. Zwiebel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ab14eb4af79571986a0d0a4861812c6
https://doi.org/10.1016/b978-1-4557-2865-7.00116-8

Correspondence

Autor: Panayiotis A. Ellinas, Fred Rosner, Juan C. Jaume

Publikováno v: The American Journal of Medicine. 89:696

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f42085a1cc941032bf419eb6be55aa6a
https://doi.org/10.1016/0002-9343(90)90201-n