Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Juan C, Carril"'
Autor:
Ramón Cacabelos, Vinogran Naidoo, Olaia Martínez-Iglesias, Lola Corzo, Natalia Cacabelos, Rocío Pego, Juan C. Carril
Publikováno v:
Life, Vol 12, Iss 3, p 460 (2022)
Alzheimer’s disease (AD) is a priority health problem with a high cost to society and a large consumption of medical and social resources. The management of AD patients is complex and multidisciplinary. Over 90% of patients suffer from concomitant
Externí odkaz:
https://doaj.org/article/4857e8b2184348ddb68d2a0e563cf036
Autor:
Ramón Cacabelos, Juan C Carril, Lola Corzo, Rocío Pego, Natalia Cacabelos, Margarita Alcaraz, Adriana Muñiz, Olaia Martínez-Iglesias, Vinogran Naidoo
Publikováno v:
Pharmacogenomics. 24:27-57
Anxiety and depression coexist with cognitive impairment in Alzheimer's disease along with other concomitant disorders (>60%), which require multipurpose treatments. Polypharmaceutical regimens cause drug–drug interactions and adverse drug reaction
Autor:
Ramón Cacabelos, Juan C. Carril, Lola Corzo, Lucía Fernández-Novoa, Rocío Pego, Natalia Cacabelos, Pablo Cacabelos, Margarita Alcaraz, Iván Tellado, Vinogran Naidoo
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 366 (2021)
Background: Mood disorders represent a risk factor for dementia and are present in over 60% of cases with Alzheimer’s disease (AD). More than 80% variability in drug pharmacokinetics and pharmacodynamics is associated with pharmacogenetics. Methods
Externí odkaz:
https://doaj.org/article/7665d2b79dba451cba8d85d380b97617
Autor:
Ramón, Cacabelos, Vinogran, Naidoo, Olaia, Martínez-Iglesias, Lola, Corzo, Natalia, Cacabelos, Rocío, Pego, Juan C, Carril
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2547
Alzheimer's disease (AD) is a priority health problem in developed countries with a high cost to society. Approximately 20% of direct costs are associated with pharmacological treatment. Over 90% of patients require multifactorial treatments, with ri
Autor:
Ramón Cacabelos, Iván Carrera, Natalia Cacabelos, Lola Corzo, Juan C. Carril, Vinogran Naidoo, Ramón Alejo, Olaia Martínez-Iglesias, Susana Rodríguez
Publikováno v:
Current Pharmacogenomics and Personalized Medicine. 17:159-171
Background: Neurodegenerative disorders are one of the major health problems in Western countries. Genetic and epigenetic mechanisms play crucial roles in the origin and progression of these disorders. DNA methylation is the most widely studied epige
Autor:
Ramón Cacabelos, Juan C. Carril, Vinogran Naidoo, Natalia Cacabelos, Gjumrakch Aliev, Iván Carrera, Olaia Martínez
Publikováno v:
Drug Development Research. 82:695-706
Atremorine is a potent dopamine (DA) enhancer obtained by nondenaturing biotechnological processes from a genetic species of Vicia faba. Atremorine affects the neuronal dopaminergic system by acting as a neuroprotective agent against Parkinson's dise
Autor:
Ramón Cacabelos, Juan C. Carril, Marcos Santiago, Joaquin Guerra, Margarita Alcaraz, Lola Corzo
Publikováno v:
Current Pharmacogenomics and Personalized Medicine. 17:114-124
Background: Polymorphisms of selected inflammatory and metabolic genes have been described in the etiology of chronic rhinosinusitis, and these effects can be explained on a pharmacogenetic basis. Objective: The purpose of this study was to examine w
Autor:
Antón Álvarez, Verónica Couceiro, Susana Rodríguez, Ángela Casas, Margarita Alcaraz, Laura Nebril, Iván Tellado, Iván Carrera, Lola Corzo, Valter Lombardi, Adam McKay, Juan C. Carril, Ramón Cacabelos, Rocío Martínez-Bouza, Lucía Fernández-Novoa
Publikováno v:
Pharmaceuticals, Vol 3, Iss 10, Pp 3040-3100 (2010)
About 80% of functional genes in the human genome are expressed in the brain and over 1,200 different genes have been associated with the pathogenesis of CNS disorders and dementia. Pharmacogenetic studies of psychotropic drug response have focused o
Externí odkaz:
https://doaj.org/article/d0d0341d7b9840ac840829d3833dbe49
Autor:
Ramón Cacabelos, Vinogran Naidoo, Olaia Martínez-Iglesias, Lola Corzo, Natalia Cacabelos, Rocío Pego, Juan C. Carril
Publikováno v:
Methods in Molecular Biology ISBN: 9781071625729
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b96d5111ef00e8ae793dc41713a6bf7
https://doi.org/10.1007/978-1-0716-2573-6_13
https://doi.org/10.1007/978-1-0716-2573-6_13
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 13302, p 13302 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 13302, p 13302 (2021)
Adverse drug reactions (ADRs) rank as one of the top 10 leading causes of death and illness in developed countries. ADRs show differential features depending upon genotype, age, sex, race, pathology, drug category, route of administration, and drug