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Autor:
Osvaldo Cox, Beatriz Zayas, Wigberto J. Hernandez, Marisol Cordero, Maria Terron, Antonio E. Alegria, Juan Beyley
Publikováno v:
Toxicology in Vitro. 21:1155-1164
The DNA binding capacity of two nitro-substituted benzazolo[3,2-a]quinolinium chlorides (NBQs), NBQ-38 and NBQ-95, was evaluated upon their enzymatic reduction with hypoxanthine (HX)/xanthine oxidase (XO) under anaerobic conditions. In the presence o