Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Juan B De Sanctis"'
Autor:
Gabriella Wojewodka, Juan B De Sanctis, Joanie Bernier, Julie Bérubé, Heather G Ahlgren, Jim Gruber, Jennifer Landry, Larry C Lands, Dao Nguyen, Simon Rousseau, Andrea Benedetti, Elias Matouk, Danuta Radzioch
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88567 (2014)
Pulmonary exacerbations (PEs) cause significant morbidity and can severely impact disease progression in cystic fibrosis (CF) lung disease, especially in patients who suffer from recurrent PEs. The assessments able to predict a future PE or a recurre
Externí odkaz:
https://doaj.org/article/2793943f2127415e8008b604a02cb010
Autor:
Claude Lachance, Gabriella Wojewodka, Tom A A Skinner, Claudine Guilbault, Juan B De Sanctis, Danuta Radzioch
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74875 (2013)
We previously identified Fragile X-related protein 1 (FXR1) as an RNA-binding protein involved in the post-transcriptional control of TNF and other cytokines in macrophages. Macrophages derived from FXR1-KO mice overexpress several inflammatory cytok
Externí odkaz:
https://doaj.org/article/3dcb8abab53a45ea8b6d179c7f5c9337
Autor:
Amrit Singh, Masatsugu Yamamoto, Sarah H Y Kam, Jian Ruan, Gail M Gauvreau, Paul M O'Byrne, J Mark FitzGerald, Robert Schellenberg, Louis-Philippe Boulet, Gabriella Wojewodka, Cynthia Kanagaratham, Juan B De Sanctis, Danuta Radzioch, Scott J Tebbutt
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67907 (2013)
Some asthmatic individuals undergoing allergen inhalation challenge develop an isolated early response whereas others develop a dual response (early plus late response). In the present study we have used transcriptomics (microarrays) and metabolomics
Externí odkaz:
https://doaj.org/article/3be8355a3e9c42fa9d132d399b6bf561
Autor:
Zuleima Blanco, Esteban Fernandez-Moreira, Michael R. Mijares, Carmen Celis, Gricelis Martínez, Juan B. De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdůch, Ali Mijoba, Yael García, Xenón Serrano, Nahum Herrera, Jhonny Correa-Abril, Yonathan Parra, Jorge Ángel, Hegira Ramírez, Jaime E. Charris
Publikováno v:
Molecules, Vol 27, Iss 17, p 5626 (2022)
The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensively documented. The use of common drugs in the treatment of these pathologies invites us to search for new molecules with these characteristics. In this
Externí odkaz:
https://doaj.org/article/2f9fecb0b6884c4cb8a3b7f2b739e2f1
Autor:
Radu A. Paun, Daciana C. Dumut, Amanda Centorame, Thusanth Thuraisingam, Marian Hajduch, Martin Mistrik, Petr Dzubak, Juan B. De Sanctis, Danuta Radzioch, Maryam Tabrizian
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 640 (2022)
The metal complex copper diethyldithiocarbamate (CuET) induces cancer cell death by inhibiting protein degradation and induces proteotoxic stress, making CuET a promising cancer therapeutic. However, no clinical formulation of CuET exists to date as
Externí odkaz:
https://doaj.org/article/9a7a1378cb3244ff93fef87229b73e23
Autor:
José L Peréz-Vicuña, Juan B. De Sanctis, Wheeler Torres, Mervin Chávez-Castillo, Clímaco Cano, Valmore Bermúdez, Joselyn Rojas-Quintero, Maricarmen Chacín, Yosselin Gómez, Rubén Carrasquero, María P. Díaz, Paola Ramírez, Manuel Velasco
Publikováno v:
Current Pharmaceutical Design. 27:4434-4451
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that involves a pathological inflammatory response against articular cartilage in multiple joints throughout the body. It is a complex disorder associated with comorbidities such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9815d1c815d1fe364328f10cf80e77
https://doi.org/10.2174/1381612827666210525164734
https://doi.org/10.2174/1381612827666210525164734
Autor:
Jenny V. Garmendia, Juan B. De Sanctis
Publikováno v:
Immuno, Vol 1, Iss 11, Pp 174-193 (2021)
NK cells are lymphocytes involved in the innate and adaptative immune response. These cells are located in peripheral blood and tissues with ample functions, from immune vigilant to tolerogenic reactions. In the endometrium, NK cell populations vary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bae87f97d0ac081831903e73e7b104
https://doi.org/10.3390/immuno1030011
https://doi.org/10.3390/immuno1030011
Autor:
Marian Hajduch, Nicolas E. Bianco, Michael Mijares, Gricelis Martínez, Maria Johanna Peña, Juan B. De Sanctis, I. Blanca, Alexis Garcia, Daniela Cerezo-Wallis, Camilo Di Giulio, Danuta Radzioch, Jenny V. Garmendia
Publikováno v:
Gaceta Médica de Caracas. 128:290-295
El cáncer es una enfermedad compleja en el cual se han utilizado numerosos tratamientos. El mayor avance en tratamiento ha sido el uso de inhibidores de puntos de control, disminuyendo la carga tumoral. La esperanza de vida de los pacientes con cán
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f6ec9395a00adfe9b172cd6333083b
https://doi.org/10.47307/gmc.2020.128.3.7
https://doi.org/10.47307/gmc.2020.128.3.7
Autor:
Danuta Radzioch, Mina Youssef, Marian Hajduch, Basil J. Petrof, Juhi Shah, Juan B. De Sanctis, Daciana Catalina Dumut
Publikováno v:
Lung. 198:459-469
Cystic fibrosis (CF) is a progressive disease which causes a continuous decline in lung capacity with age. Our study aimed to investigate the age-dependent deterioration in lung function and the effects of treatment with Fenretinide formulation (LAU-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c98a835a278b647855aa87e598b273
https://doi.org/10.1007/s00408-020-00353-2
https://doi.org/10.1007/s00408-020-00353-2
Autor:
Marian Hajduch, Daciana Catalina Dumut, Danuta Radzioch, Mina Youssef, Juhi Shah, Juan B. De Sanctis, Anna K. Naumova
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 373:476-487
Zona pellucida binding protein 2 (Zpbp2) and ORMDL sphingolipid biosynthesis regulator 3 (Ormdl3), mapped downstream of Zpbp2, were identified as two genes associated with airway hyper-responsiveness (AHR). Ormdl3 gene product has been shown to regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d61dc7e1b08509f590708e1db9a9ec1f
https://doi.org/10.1124/jpet.119.263715
https://doi.org/10.1124/jpet.119.263715