Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Juan Angel Fresno Vara"'
Autor:
Angelo Gámez-Pozo, Iker Sánchez-Navarro, Manuel Nistal, Enrique Calvo, Rosario Madero, Esther Díaz, Emilio Camafeita, Javier de Castro, Juan Antonio López, Manuel González-Barón, Enrique Espinosa, Juan Angel Fresno Vara
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7731 (2009)
BACKGROUND:Proteomics is expected to play a key role in cancer biomarker discovery. Although it has become feasible to rapidly analyze proteins from crude cell extracts using mass spectrometry, complex sample composition hampers this type of measurem
Externí odkaz:
https://doaj.org/article/3758d45e9802400c8d8805be7f8c9549
Autor:
Enrique Espinosa, Iker Sánchez-Navarro, Angelo Gámez-Pozo, Alvaro Pinto Marin, David Hardisson, Rosario Madero, Andrés Redondo, Pilar Zamora, Belén San José Valiente, Marta Mendiola, Manuel González Barón, Juan Angel Fresno Vara
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5911 (2009)
INTRODUCTION: Gene profiling may improve prognostic accuracy in patients with early breast cancer, but this technology is not widely available. We used commercial assays for qRT-PCR to assess the performance of the gene profiles included in the 70-Ge
Externí odkaz:
https://doaj.org/article/bd6fb78093714c29bc4d6a6a052b1ca5
Autor:
Marta Mendiola, Jorge Barriuso, Andrés Redondo, Adrián Mariño-Enríquez, Rosario Madero, Enrique Espinosa, Juan Angel Fresno Vara, Iker Sánchez-Navarro, Ginés Hernández-Cortes, Pilar Zamora, Elia Pérez-Fernández, María Miguel-Martín, Asunción Suárez, José Palacios, Manuel González-Barón, David Hardisson
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e4051 (2008)
BACKGROUND: Ovarian carcinoma is the most important cause of gynecological cancer-related mortality in Western societies. Despite the improved median overall survival in patients receiving chemotherapy regimens such as paclitaxel and carboplatin comb
Externí odkaz:
https://doaj.org/article/ea7e833d93d04d07873dba09f27b7498
Autor:
Lucia Trilla-Fuertes, Guillermo Prado-Vazquez, Angelo Gámez-Pozo, Rocio Lopez-Vacas, Maria Isabel Lumbreras Herrera, Virtudes Soriano, Fernando Garicano, Maria Jose Lecumberri, Maria Rodriguez, Margarita Majem, Elisabeth Perez, Maria Gonzalez-Cao, Juana Oramas, Alejandra Magdaleno, Joaquin Fra, Alfonso Martin, Monica Corral, Teresa Puertolas, Juan Angel Fresno Vara, Enrique Espinosa
Publikováno v:
Cancer Research. 82:5416-5416
Background: Prediction of response to immunotherapy remains an unmet need in the field of advanced melanoma. Methods: Computational analyses, including probabilistic graphical models, sparse k-means, and consensus cluster, were used to characterize m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d529f480afca1b478160c1657f261e
https://doi.org/10.1158/1538-7445.am2022-5416
https://doi.org/10.1158/1538-7445.am2022-5416
Autor:
Alvaro Pinto, Lucía Trilla-Fuertes, Jesus Miranda Poma, Naveen Vasudev, Eugenia García-Fernández, Rocio Lopez Vacas, Natalia Miranda, Michelle Wilson, Elena López-Camacho, Ana Pertejo, Maria Isabel Lumbreras-Herrera, Joanne C Brown, Andrea Zapater-Moros, Guillermo De Velasco, Daniel E. Castellano, María Pilar González-Peramato, Enrique Espinosa, Rosamonde Banks, Juan Angel Fresno-Vara, Angelo Gámez-Pozo
Publikováno v:
Journal of Clinical Oncology. 40:e16519-e16519
e16519 Background: Prognosis of localized clear cell renal cell carcinoma (ccRCC) patients is estimated by nomograms based on clinico-pathological factors. However, clinical guidelines do not recommend their use. Recently, pembrolizumab has demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f97c803eb5eb3a8ea0830f6cbc93819
https://doi.org/10.1200/jco.2022.40.16_suppl.e16519
https://doi.org/10.1200/jco.2022.40.16_suppl.e16519
Autor:
Sonia Alcalá, Lara Villarino, Laura Ruiz-Cañas, José R. Couceiro, Miguel Martínez-Calvo, Adrián Palencia-Campos, Diego Navarro, Pablo Cabezas-Sainz, Iker Rodriguez-Arabaolaza, Alfonso Cordero-Barreal, Lucia Trilla-Fuertes, Juan A. Rubiolo, Sandra Batres-Ramos, Mireia Vallespinos, Cristina González-Páramos, Jéssica Rodríguez, Angelo Gámez-Pozo, Juan Ángel Fresno Vara, Sara Fra Fernández, Amparo Benito Berlinches, Nicolás Moreno-Mata, Ana María Torres Redondo, Alfredo Carrato, Patrick C. Hermann, Laura Sánchez, Susana Torrente, Miguel Ángel Fernández-Moreno, José L. Mascareñas, Bruno Sainz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-27 (2024)
Abstract Background Previous studies by our group have shown that oxidative phosphorylation (OXPHOS) is the main pathway by which pancreatic cancer stem cells (CSCs) meet their energetic requirements; therefore, OXPHOS represents an Achille’s heel
Externí odkaz:
https://doaj.org/article/a0e8a35f5983431287f4bb493ff1d8e0
Autor:
Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Joan Maurel, Rocio Garcia-Carbonero, Jaume Capdevila, Laura G-Pastrián, Marta Mendiola, Cristina Peña, Rocío López-Vacas, Miriam Cuatrecasas, Pilar García-Alfonso, Ricardo Ramos-Ruiz, Carlos Llorens, Ismael Ghanem, Carles Conill, Victoria Heredia-Soto, Ángel Campos-Barros, Juan Ángel Fresno Vara, Jaime Feliu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Squamous cell carcinoma is the most frequent histologic type of anal carcinoma. The standard of care since the 1970s has been a combination of 5-fluorouracil, mitomycin C, and radiotherapy. This treatment is very effective in T1/T2 tumors (a
Externí odkaz:
https://doaj.org/article/d4fe26f9fdff4908953ce34c605cf410
Autor:
Elena López-Camacho, Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Irene Dapía, Rocío López-Vacas, Andrea Zapater-Moros, María Isabel Lumbreras-Herrera, Pedro Arias, Pilar Zamora, Juan Ángel Fresno Vara, Enrique Espinosa
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 149, Iss , Pp 112844- (2022)
The triple-negative breast cancer (TNBC) subtype comprises approximately 15% of all breast cancers and is associated with poor long-term outcomes. Classical chemotherapy remains the standard of treatment, with toxicity and resistance being major limi
Externí odkaz:
https://doaj.org/article/27c9f7d5fafb40a5a3d190aa5fbca735
Autor:
José Manuel, García-Martínez, Juan Angel, Fresno Vara, Pedro, Lastres, Carmelo, Bernabéu, Pablo Ortiz, Betés, Jorge, Martín-Pérez
Publikováno v:
Biochemical pharmacology. 65(2)
Metamizol is an analgesic and antipyretic agent that can induce agranulocytosis in certain patients. However, its effects on granulocyte viability and differentiation have been poorly evaluated. Here we analysed the effects of metamizol and its activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce273da430ea3c5be5ca74c5b46cdd61
https://pubmed.ncbi.nlm.nih.gov/12504796
https://pubmed.ncbi.nlm.nih.gov/12504796
Autor:
Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Elena López-Camacho, Guillermo Prado-Vázquez, Andrea Zapater-Moros, Rocío López-Vacas, Jorge M. Arevalillo, Mariana Díaz-Almirón, Hilario Navarro, Paloma Maín, Enrique Espinosa, Pilar Zamora, Juan Ángel Fresno Vara
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Metabolomics has a great potential in the development of new biomarkers in cancer and it has experiment recent technical advances. Methods In this study, metabolomics and gene expression data from 67 localized (stage I to IIIB) br
Externí odkaz:
https://doaj.org/article/b0992cc46a1c43dca0e68fab2cd0fd3e