Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Juan Alberto Mondotte"'
Autor:
Marcelo M. Samsa, Cecilia Alvarez, Nestor Gabriel Iglesias, Andrea V. Gamarnik, Laura Andrea Byk, Federico Andres de Maio, Juan Alberto Mondotte
Publikováno v:
Traffic. 16:962-977
Dengue viruses cause the most important human viral disease transmitted by mosquitoes. In recent years, a great deal has been learned about molecular details of dengue virus genome replication; however, little is known about genome encapsidation and
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Little is known about the mechanism of flavivirus genome encapsidation. Here, functional elements of the dengue virus (DENV) capsid (C) protein were investigated. Study of the N-terminal region of DENV C has been limited by the presence of overlappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46f854b8f2f2b39ac42135daf8f53ee
http://jvi.asm.org/content/86/2/1046.long
http://jvi.asm.org/content/86/2/1046.long
Autor:
Dominique Schols, Mathy Froeyen, Suzanne J.F. Kaptein, Boris Pastorino, Tine De Burghgraeve, Michael Jacobs, Xavier de Lamballerie, Juan Alberto Mondotte, Piet Herdewijn, Andrea V. Gamarnik, Ferenc Sztaricskai, Marijke Alen, Johan Neyts
A doxorubicin derivate, SA-17, that carries a squaric acid amide ester moiety at the carbohydrate (-Ldaunosaminyl) group was identified as a selective inhibitor of in vitro dengue virus (DENV) serotype 2 replication (50% effective concentration [EC50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70e1f5dd7c3ddf0b63a0533dc460a75
https://europepmc.org/articles/PMC2981273/
https://europepmc.org/articles/PMC2981273/
Autor:
Iranaia Assunção-Miranda, Juan Alberto Mondotte, Patrícia T. Bozza, Andrea T. Da Poian, Nestor Gabriel Iglesias, Marcelo M. Samsa, Andrea V. Gamarnik, Giselle Barbosa-Lima
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 5, Iss 10, p e1000632 (2009)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Pathogens, Vol 5, Iss 10, p e1000632 (2009)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Dengue virus is responsible for the highest rates of disease and mortality among the members of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating an urgent need of prophylactic vaccines and antivirals. In recent
Autor:
Claudia Veronica Filomatori, Diego E. Alvarez, Andrea V. Gamarnik, Maria Fernanda Lodeiro, Silvana Fucito, Juan Alberto Mondotte
Publikováno v:
New Treatment Strategies for Dengue and Other Flaviviral Diseases: Novartis Foundation Symposium 277
Sequences and structures present at the 5' and 3' UTRs of RNA viruses play crucial roles in the initiation and regulation of translation, RNA synthesis and viral assembly. In dengue virus, as well as in other mosquito-borne flaviviruses, the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52105fc2b8fcf295d5b50c3efde55fa2
https://doi.org/10.1002/0470058005.ch9
https://doi.org/10.1002/0470058005.ch9
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2007, 81 (13), pp.7136-7148. ⟨10.1128/JVI.00116-07⟩
Journal of Virology, 2007, 81 (13), pp.7136-7148. ⟨10.1128/JVI.00116-07⟩
Journal of Virology, American Society for Microbiology, 2007, 81 (13), pp.7136-7148. ⟨10.1128/JVI.00116-07⟩
Journal of Virology, 2007, 81 (13), pp.7136-7148. ⟨10.1128/JVI.00116-07⟩
Dengue virus envelope protein (E) contains two N-linked glycosylation sites, at Asn-67 and Asn-153. The glycosylation site at position 153 is conserved in most flaviviruses, while the site at position 67 is thought to be unique for dengue viruses. N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f1564ef2fd34198c5108d55443d381
https://hal.inrae.fr/hal-03331578
https://hal.inrae.fr/hal-03331578
Autor:
Michael Jacobs, Maria N. Preobrazhenskaya, Boris Pastorino, Tine De Burghgraeve, Suzanne J.F. Kaptein, Xavier de Lamballerie, Andrea V. Gamarnik, Johan Neyts, Juan Alberto Mondotte, Nilda V. Ayala-Nunez, Jolanda M. Smit, Svetlana S. Printsevskaya
Publikováno v:
PLoS ONE; Vol 7
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, 7(5):e37244. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 7, Iss 5, p e37244 (2012)
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE, 7(5):e37244. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 7, Iss 5, p e37244 (2012)
There is an urgent need for potent inhibitors of dengue virus (DENV) replication for the treatment and/or prophylaxis of infections with this virus. We here report on an aglycon analogue of the antibiotic teicoplanin (code name LCTA-949) that inhibit