Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Juan A. Sanchez-Arias"'
Autor:
Edurne San José-Enériz, Xabier Agirre, Obdulia Rabal, Amaia Vilas-Zornoza, Juan A. Sanchez-Arias, Estibaliz Miranda, Ana Ugarte, Sergio Roa, Bruno Paiva, Ander Estella-Hermoso de Mendoza, Rosa María Alvarez, Noelia Casares, Victor Segura, José I. Martín-Subero, François-Xavier Ogi, Pierre Soule, Clara M. Santiveri, Ramón Campos-Olivas, Giancarlo Castellano, Maite Garcia Fernandez de Barrena, Juan Roberto Rodriguez-Madoz, Maria José García-Barchino, Juan Jose Lasarte, Matias A Avila, Jose Angel Martinez-Climent, Julen Oyarzabal, Felipe Prosper
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Epigenetic drugs are emerging as a powerful therapeutic option for cancer treatment. Here, the authors synthesized selective chemical probes that simultaneously inhibit the G9a and DNMTs methyltransferase activity and demonstrate their anti-tumour ac
Externí odkaz:
https://doaj.org/article/286f3156e84448249eb1c05f274be064
Autor:
Nicole S, York, Juan C, Sanchez-Arias, Alexa C H, McAdam, Joel E, Rivera, Laura T, Arbour, Leigh Anne, Swayne
Publikováno v:
Frontiers in Cardiovascular Medicine. 9
The ANK2 gene encodes for ankyrin-B (ANKB), one of 3 members of the ankyrin family of proteins, whose name is derived from the Greek word for anchor. ANKB was originally identified in the brain (B denotes “brain”) but has become most widely known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4147bd8dd208810cee6231b8ade8cb8
https://doi.org/10.3389/fcvm.2022.964675
https://doi.org/10.3389/fcvm.2022.964675
Autor:
Juan C. Sanchez-Arias, Brant E. Isakson, Alexander W. Lohman, Silvia Penuela, Abigail G. Wolpe, Miranda E. Good, X. Michael Koval, Leigh Anne Swayne, Chen Seng Ng, Scott R. Johnstone, Victor E. Laubach
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Anatomy and Cell Biology Publications
Anatomy and Cell Biology Publications
Copyright © 2020 the American Physiological Society Pannexin 1 (PANX1) is a ubiquitously expressed, channel-forming protein found in a number of tissues throughout the body (e.g., lung, vasculature, liver, central nervous system, immune system) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12a188afec7a7c70aa9377f0461004b
http://europepmc.org/articles/PMC7347959
http://europepmc.org/articles/PMC7347959
Publikováno v:
Biochemistry and Cell Biology. 98:299-306
Ankyrin-B (AnkB) is scaffolding protein that anchors integral membrane proteins to the cardiomyocyte cytoskeleton. We recently identified an AnkB variant, AnkB p.S646F (ANK2 c.1937 C>T) associated with a phenotype ranging from predisposition for card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c427fe46c3ee40a52143b8ca6788d0
https://doi.org/10.1139/bcb-2019-0082
https://doi.org/10.1139/bcb-2019-0082
Autor:
Juan C. Sanchez-Arias, Micaël Carrier, Simona D. Frederiksen, Olga Shevtsova, Chloe McKee, Emma van der Slagt, Elisa Gonçalves de Andrade, Hai Lam Nguyen, Penelope A. Young, Marie-Ève Tremblay, Leigh Anne Swayne
Publikováno v:
Frontiers in Neuroanatomy
Frontiers in Neuroanatomy, Vol 15 (2021)
Frontiers in Neuroanatomy, Vol 15 (2021)
The ever-expanding availability and evolution of microscopy tools has enabled ground-breaking discoveries in neurobiology, particularly with respect to the analysis of cell-type density and distribution. Widespread implementation of many of the elega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6fb914ec4808dc33cded127b0c0f07
Macropinocytosis is an endocytic process that allows cells to respond to changes in their environment by internalizing nutrients and cell surface proteins, as well as modulating cell size. Here, we identify that adenosine triphosphate (ATP) triggers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60ed6fcbd8de3bd49b556996914fb59
https://doi.org/10.1101/2020.11.19.389072
https://doi.org/10.1101/2020.11.19.389072
Publikováno v:
eNeuro
The integration of neurons into networks relies on the formation of dendritic spines. These specialized structures arise from dynamic filopodia-like dendritic protrusions. It was recently reported that cortical neurons lacking the channel protein pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026498cbe6bb09cfae38593aa2692f38
https://pubmed.ncbi.nlm.nih.gov/32737184
https://pubmed.ncbi.nlm.nih.gov/32737184
The integration of neurons into networks relies on the formation of dendritic spines. These specialized structures arise from dynamic filopodia-like spiny protrusions. Recently, it was discovered that cortical neurons lacking the channel protein Pann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c900cc81a2620df0065198864a7862
Autor:
Nicole York, Afnan Juma, Olga Shevtsova, Leigh Anne Swayne, Haley A. Vecchiarelli, Juan C. Sanchez-Arias, Penelope A. Young, Emma van der Slagt, Rebecca C. Candlish, Marie-Ève Tremblay
Publikováno v:
Pharmacology & Therapeutics. 225:107840
Purinergic signaling encompasses the cycle of adenosine 5' triphosphate (ATP) release and its metabolism into nucleotide and nucleoside derivatives, the direct release of nucleosides, and subsequent receptor-triggered downstream intracellular pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0f0bc548177bd3ad12fc904996d52b
https://doi.org/10.1016/j.pharmthera.2021.107840
https://doi.org/10.1016/j.pharmthera.2021.107840
The Pannexin 1 (Panx1) channel-forming protein is enriched in the central nervous system, and has been associated with several critical neurodevelopmental and plasticity functions; these include dendritic spine formation, neuronal network development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f06c7c3dde50949e552b14e34a3f257b
https://doi.org/10.1101/801563
https://doi.org/10.1101/801563