UHRF genes regulate programmed interdigital tissue regression and chondrogenesis in the embryonic limb

Autor: Juan M. Hurle, Carlos I. Lorda-Diez, Juan A. García-Porrero, Cristina Sanchez-Fernandez, Juan A. Montero

Publikováno v: Cell Death Dis. 2019 10(5):347
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Cell Death and Disease, Vol 10, Iss 5, Pp 1-14 (2019)
Cell Death & Disease

The primordium of the limb contains a number of progenitors far superior to those necessary to form the skeletal components of this appendage. During the course of development, precursors that do not follow the skeletogenic program are removed by cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2674c83b6fb914eb4ee19a2be55717dd
http://hdl.handle.net/10902/18311

Heschl’s gyrus fiber intersection area: a new insight on the connectivity of the auditory-language hub

Autor: Carlos Velasquez, Leticia Fernández, Juan Martino, Enrique Marco de Lucas, Juan A García Porrero

Publikováno v: Neurosurgical Focus. 48:E7

OBJECTIVEThe functional importance of the superior temporal lobe at the level of Heschl’s gyrus is well known. However, the organization and function of these cortical areas and the underlying fiber tracts connecting them remain unclear. The goal o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6669bcd6c3768095a55e4febb00167d
https://doi.org/10.3171/2019.11.focus19778

Apoptosis during embryonic tissue remodeling is accompanied by cell senescence

Autor: Carlos I. Lorda-Diez, Juan A. García-Porrero, Juan M. Hurle, Beatriz Garcia-Riart, Joaquín Rodríguez-León, Juan A. Montero

Publikováno v: Aging (Albany NY). 2015 Nov;7(11):974-85
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Aging (Albany NY)

This study re-examined the dying process in the interdigital tissue during the formation of free digits in the developing limbs. We demonstrated that the interdigital dying process was associated with cell senescence, as deduced by induction of β-ga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdccbe9dcb94a1786b4dd247561fff0
https://doi.org/10.18632/aging.100844

Four and a half domain 2 (FHL2) scaffolding protein is a marker of connective tissues of developing digits and regulates fibrogenic differentiation of limb mesodermal progenitors

Autor: Jesús Chimal-Monroy, Cristina Sanchez-Fernandez, Juan A. García-Porrero, Juan M. Hurle, Carlos I. Lorda-Diez, Juan A. Montero

Publikováno v: Journal of tissue engineering and regenerative medicine. 12(4)

Four and a half LIM domain 2 (FHL2) is a multifunctional scaffolding protein of well-known function regulating cell signalling cascades and gene transcription in cancer tissues. However, its function in embryonic systems is poorly characterized. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0882d190256c4d5cd9ddb89da2479777
https://pubmed.ncbi.nlm.nih.gov/29330921

Sox9 Expression in Amniotes: Species-Specific Differences in the Formation of Digits

Autor: Carlos I. Lorda-Diez, Juan A. García-Porrero, Jesús Chimal-Monroy, Javier Francisco-Morcillo, Juan M. Hurle, Juan A. Montero

Publikováno v: Front. Cell Dev. Biol., 23 March 2017
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Frontiers in Cell and Developmental Biology

In tetrapods the digit pattern has evolved to adapt to distinct locomotive strategies. The number of digits varies between species or even between hindlimb and forelimb within the same species. These facts illustrate the plasticity of embryonic limb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701a7a328583034b2239ef1c0ba1dc48
http://hdl.handle.net/10902/11831