Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Juan A. Diez-Pardo"'
Publikováno v:
Pediatric Surgery International. 19:331-334
Nitrofen induces in rats diaphragmatic hernia (CDH) with heart and lung hypoplasia by a mechanism involving oxidation. The aim of this study was to examine if prenatal administration of the anti-oxidant agent vitamin E (VitE) prevents to some extent
Publikováno v:
Pediatric Surgery International. 19:355-358
Prenatal exposure of rat embryos to retinoic acid induces severe malformations involving various organs. The mechanisms of this embryopathy are known only in part. This study describes the malformations of the neural crest-derived organs in this mode
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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8 pages, 6 figures.
The thyroid transcription factor (TTF)-1 has an essential role in lung morphogenesis and development. It is involved in the transcription of surfactant proteins (SP), which are critical in respiratory function. Neonates with
The thyroid transcription factor (TTF)-1 has an essential role in lung morphogenesis and development. It is involved in the transcription of surfactant proteins (SP), which are critical in respiratory function. Neonates with
Publikováno v:
Pediatric Surgery International. 15:188-191
Prenatal exposure to nitrofen induces lung hypoplasia and diaphragmatic hernias very similar to those in human disease, but the mechanisms are still unknown. Thyroid transcription factor 1 (TTF-1) is involved in lung ontogeny and regulation of the ex
Autor:
Juan A. Tovar, Aranzazu Arnaiz, Jose I. Alvarez, Huimin Xia, Lucia Migliazza, Juan A. Diez-Pardo, Luisa F. Alfonso
Publikováno v:
Journal of Pediatric Surgery. 34:706-711
Background/Purpose: Heart hypoplasia is associated with congenital diaphragmatic hernia (CDH) and decisively influences survival rate. This study examines whether nitrofen-exposed fetal rats have heart hypoplasia. Methods: Pregnant rats received eith
Publikováno v:
Journal of Pediatric Surgery. 34:536-539
Malformations of the tracheobronchial tree may account for postoperative respiratory symptoms in patients with esophageal atresia (EA). This study examines the respiratory tract in fetal rats with EA induced by Adriamycin.Time-mated female rats were
Publikováno v:
Digestive Diseases and Sciences. 44:2283-2289
This study tests the hypothesis that eitherselective or combined destruction of the loweresophageal sphincter and the diaphragmatic crural slingshould induce reflux in the rat. Pull-through perfusion manometry was performed before and after loweresop
Autor:
Alberto Mate, Juan A. Tovar, Sandra Montedonico, Jorge Godoy, Anne K Possögel, Juan A. Diez-Pardo
Publikováno v:
Digestive Diseases and Sciences. 44:2449-2455
The two components of the gastroesophageal barrier, the sphincter and the crural sling, closely overlap in humans, whereas they are widely separated in the rat. This investigation correlates the anatomical components of the barrier and their manometr
Publikováno v:
Journal of Pediatric Surgery. 33:606-612
Purpose: The aim of this study was to describe the dysmorphogenetic process leading to esophageal atresia and tracheoesophageal fistula (EA + TEF) in the recently developed Adriamycin model of the malformation. Methods: Time-mated pregnant rats were
Publikováno v:
Journal of Pediatric Surgery. 32:1310-1313
Gastroesophageal reflux (GER) is increasingly reported after surgical repair of congenital diaphragmatic hernia (CDH) and eventration. The aim of this study was to test the hypothesis that transdiaphragmatic pressure gradients are increased and that