Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Juan A. Asenjo"'
Autor:
Rishi Vachaspathy Astakala, Gagan Preet, Ahlam Haj Hasan, Ria Desai, Juan A. Asenjo, Barbara Andrews, William T. A. Harrison, Rainer Ebel, Marcel Jaspars
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1822 (2024)
Microorganisms are a valuable source of pharmaceutically active chemicals, serving as scaffolds for synthesis as well as lead structures. Investigating novel biomes frequently yields intriguing chemistry; the Atacama Desert in Chile is one such examp
Externí odkaz:
https://doaj.org/article/15a6faa331ac4d7a82c43996116937f3
Autor:
Karen Y. Oróstica, Juan Saez-Hidalgo, Pamela R. de Santiago, Solange Rivas, Sebastian Contreras, Gonzalo Navarro, Juan A. Asenjo, Álvaro Olivera-Nappa, Ricardo Armisén
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Recently, extensive cancer genomic studies have revealed mutational and clinical data of large cohorts of cancer patients. For example, the Pan-Lung Cancer 2016 dataset (part of The Cancer Genome Atlas project), summarises the mut
Externí odkaz:
https://doaj.org/article/48c75e6dd127492abe9641717a22dadd
Publikováno v:
Marine Drugs, Vol 21, Iss 11, p 586 (2023)
Coenzyme Q (CoQ; ubiquinone) is an essential component of the respiratory chain. It is also a potent antioxidant that prevents oxidative damage to DNA, biological membranes, and lipoproteins. CoQ comprises a six-carbon ring with polar substituents th
Externí odkaz:
https://doaj.org/article/0af2138c89eb4fcbb05612f60153c5fb
Autor:
David Medina-Ortiz, Sebastian Contreras, Juan Amado-Hinojosa, Jorge Torres-Almonacid, Juan A. Asenjo, Marcelo Navarrete, Álvaro Olivera-Nappa
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Computational methods in protein engineering often require encoding amino acid sequences, i.e., converting them into numeric arrays. Physicochemical properties are a typical choice to define encoders, where we replace each amino acid by its value for
Externí odkaz:
https://doaj.org/article/8dd94a5127684fe4a9bf15f92f81a0e3
Autor:
Diego Valdebenito, Sebastián Urrutia, Allison Leyton, Yusuf Chisti, Juan A. Asenjo, Carolina Shene
Publikováno v:
Marine Drugs, Vol 21, Iss 1, p 15 (2022)
The psychrophilic marine microorganism Thraustochytrium sp. RT2316-16 can produce carotenoids as well as lipids containing the omega-3 polyunsaturated fatty acids (PUFA) eicosapentaenoic acid and docosahexaenoic acid. This work reports on the effects
Externí odkaz:
https://doaj.org/article/45e1fcc6f7014d5c8f0dbd3df42b5fad
Autor:
Rishi Vachaspathy Astakala, Gagan Preet, Bruce F. Milne, Julius Tibyangye, Valeria Razmilic, Jean Franco Castro, Juan A. Asenjo, Barbara Andrews, Rainer Ebel, Marcel Jaspars
Publikováno v:
Molecules, Vol 27, Iss 21, p 7185 (2022)
Bacteria belonging to the phylum Actinobacteria are a very good source of antibiotics, and indeed dominate the current clinical antibiotic space. This paper reports Mutactimycin AP, a new compound belonging to an anthracycline-type family of antibiot
Externí odkaz:
https://doaj.org/article/efb643557f68465e97d3108393ff7882
Publikováno v:
Marine Drugs, Vol 20, Iss 7, p 416 (2022)
The carotenogenic thraustochytrid Thraustochytrium sp. RT2316-16 was grown in batch and repeated-batch cultures using different feeds containing glucose, or glycerol, and yeast extract, for the production of lipids, phospholipids and carotenoids. RT2
Externí odkaz:
https://doaj.org/article/c9f73ee6d0bb412e885e8ca55b0aab3d
Publikováno v:
HardwareX, Vol 8, Iss , Pp e00128- (2020)
DNA electrophoresis is a fundamental technique in molecular biology that allows the separation of DNA molecules up to ~50 Kbp. Pulsed-field gel electrophoresis [PFGE] is a variation of the conventional DNA electrophoresis technique that allows the se
Externí odkaz:
https://doaj.org/article/ef639c941fcf4231b8d64657171817e8
Autor:
Allison Leyton, Liset Flores, Carolina Shene, Yusuf Chisti, Giovanni Larama, Juan A. Asenjo, Roberto E. Armenta
Publikováno v:
Marine Drugs, Vol 19, Iss 7, p 386 (2021)
Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and carotenoids are needed as human dietary supplements and are essential components in commercial feeds for the production of aquacultured seafood. Microorganisms such as thraustochytrids are
Externí odkaz:
https://doaj.org/article/3206fae8b75349bf8c5e3e94816ab4c5
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The Atacama Desert is the most extreme non-polar biome on Earth, the core region of which is considered to represent the dry limit for life and to be an analogue for Martian soils. This study focused on actinobacteria because they are keysto
Externí odkaz:
https://doaj.org/article/f1d8f84c67824c2b885c489236273fce