Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Juan A Ferrer-Bonsoms"'
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Splicing is a genetic process that has important implications in several diseases including cancer. Deciphering the complex rules of splicing regulation is crucial to understand and treat splicing-related diseases. Splicing factor
Externí odkaz:
https://doaj.org/article/aba8c8fbe95f45448647d3711341393d
Autor:
Juan A Ferrer-Bonsoms, Marian Gimeno, Danel Olaverri, Pablo Sacristan, César Lobato, Carlos Castilla, Fernando Carazo, Angel Rubio
Publikováno v:
NAR Genomics and Bioinformatics. 4
Alternative splicing (AS) plays a key role in cancer: all its hallmarks have been associated with different mechanisms of abnormal AS. The improvement of the human transcriptome annotation and the availability of fast and accurate software to estimat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4af9aea655b17579994aeeaaa3e6dc7
https://doi.org/10.1093/nargab/lqac067
https://doi.org/10.1093/nargab/lqac067
Autor:
Fernando Carazo, Carlos Castilla, Angel Rubio, Pablo Fernández-Acín, Ignacio Cassol, Juan A Ferrer-Bonsoms
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The advent of RNA-seq technologies has switched the paradigm of genetic analysis from a genome to a transcriptome-based perspective. Alternative splicing generates functional diversity in genes, but the precise functions of many individual isoforms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041fe204674ba6eade273704515dc93c
http://link.springer.com/article/10.1038/s41598-020-57974-z
http://link.springer.com/article/10.1038/s41598-020-57974-z
Publikováno v:
Bioinformatics
Motivation Isoform deconvolution is an NP-hard problem. The accuracy of the proposed solutions is far from perfect. At present, it is not known if gene structure and isoform concentration can be uniquely inferred given paired-end reads, and there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ead38dfcb2669e0b7e5a6f2c3820b1
https://europepmc.org/articles/PMC8896638/
https://europepmc.org/articles/PMC8896638/
Publikováno v:
Bioinformatics (Oxford, England).
Motivation Discover is an algorithm developed to identify mutually exclusive genomic events. Its main contribution is a statistical analysis based on the Poisson–Binomial (PB) distribution to take into account the mutation rate of genes and samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b8e0b1b16beaa124d851b3e2deb91e
https://pubmed.ncbi.nlm.nih.gov/34664620
https://pubmed.ncbi.nlm.nih.gov/34664620