Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Juan A, Marchal"'
Unveiling the microRNA landscape in pancreatic ductal adenocarcinoma patients and cancer cell models
Autor:
Grazia Fenu, Carmen Griñán-Lisón, Andrea Pisano, Aitor González-Titos, Cristiano Farace, Giovanni Fiorito, Federica Etzi, Teresa Perra, Angela Sabalic, Belén Toledo, Macarena Perán, Maria Giuliana Solinas, Alberto Porcu, Juan Antonio Marchal, Roberto Madeddu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) poses a significant challenge due to late-stage diagnoses resulting from nonspecific early symptoms and the absence of early diagnostic biomarkers. MicroRNAs (miRNAs) play a crucial role in
Externí odkaz:
https://doaj.org/article/92f9560de5734c30960654cf42e7dd4c
Autor:
María Ángeles Fernández-Mimbrera, Sofía Salido, Juan Alberto Marchal, Alfonso Alejo-Armijo
Publikováno v:
ACS Omega, Vol 9, Iss 38, Pp 39503-39512 (2024)
Externí odkaz:
https://doaj.org/article/54f103279f4541fbb292f0a6e9d14ee0
Autor:
Pedro Justicia-Lirio, María Tristán-Manzano, Noelia Maldonado-Pérez, Carmen Barbero-Jiménez, Marina Cortijo-Gutiérrez, Kristina Pavlovic, Francisco J. Molina-Estevez, Pilar Muñoz, Ana Hinckley-Boned, Juan R. Rodriguez-Madoz, Felipe Prosper, Carmen Griñán-Lison, Saúl A. Navarro-Marchal, Carla Panisello, Julia Muñoz-Ballester, Pedro A. González-Sierra, Concha Herrera, Juan A. Marchal, Francisco Martín
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102308- (2024)
Although chimeric antigen receptor (CAR) T cell therapy has revolutionized type B cancer treatment, efficacy remains limited in various lymphomas and solid tumors. Reinforcing conventional CAR-T cells to release cytokines can improve their efficacy b
Externí odkaz:
https://doaj.org/article/bffb79b98bd04d24b3575e2ddc65fa95
Autor:
Julia López de Andrés, César Rodríguez-Santana, Laura de Lara-Peña, Gema Jiménez, Germaine Escames, Juan Antonio Marchal
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101246- (2024)
Head and neck squamous cell carcinoma (HNSCC) presents a significant challenge worldwide due to its aggressiveness and high recurrence rates post-treatment, often linked to cancer stem cells (CSCs). Melatonin shows promise as a potent tumor suppresso
Externí odkaz:
https://doaj.org/article/7cbfd1e5d849460395d10bbfaa529649
Autor:
Belén Toledo, Linrui Zhu Chen, María Paniagua-Sancho, Juan Antonio Marchal, Macarena Perán, Elisa Giovannetti
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-34 (2024)
Abstract Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours are known as tumour-associated macrophages (TAMs). These specialized immune cells play crucial roles in tumour growth, angiogenesis, immune regulati
Externí odkaz:
https://doaj.org/article/04bae7a90baa4ad0a0fd1a84ab9ec11f
Autor:
José L. Blaya-Cánovas, Carmen Griñán-Lisón, Isabel Blancas, Juan A. Marchal, César Ramírez-Tortosa, Araceli López-Tejada, Karim Benabdellah, Marina Cortijo-Gutiérrez, M. Victoria Cano-Cortés, Pablo Graván, Saúl A. Navarro-Marchal, Jaime Gómez-Morales, Violeta Delgado-Almenta, Jesús Calahorra, María Agudo-Lera, Amaia Sagarzazu, Carlos J. Rodríguez-González, Tania Gallart-Aragón, Christina Eich, Rosario M. Sánchez-Martín, Sergio Granados-Principal
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-20 (2024)
Abstract Background Active targeting by surface-modified nanoplatforms enables a more precise and elevated accumulation of nanoparticles within the tumor, thereby enhancing drug delivery and efficacy for a successful cancer treatment. However, surfac
Externí odkaz:
https://doaj.org/article/7eccea89fef54fdfadb06b2ab6ab804f
Autor:
Cristina Galocha-León, Cristina Antich, Beatriz Clares-Naveros, Ana Voltes-Martínez, Juan Antonio Marchal, Patricia Gálvez-Martín
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1422 (2024)
Background/Objectives: Three-dimensional bioprinting technology has enabled great advances in the treatment of articular cartilage (AC) defects by the biofabrication of biomimetic constructs that restore and/or regenerate damaged tissue. In this sens
Externí odkaz:
https://doaj.org/article/06229a19304b4f4ebb707b51906bd3ab
Autor:
María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Marina Cortijo-Gutierréz, Pablo Tristán-Ramos, Carlos Blanco-Benítez, Kristina Pavlovic, Araceli Aguilar-González, Pilar Muñoz, Francisco J. Molina-Estevez, Valerie Griesche, Juan Antonio Marchal, Sara R. Heras, Karim Benabdellah, Francisco Martin
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 322-339 (2023)
Controlling transgene expression through an externally administered inductor is envisioned as a potent strategy to improve safety and efficacy of gene therapy approaches. Generally, inducible ON systems require a chimeric transcription factor (transa
Externí odkaz:
https://doaj.org/article/5e23d31a5c5e4bcd886b94089d46f8e8
Autor:
Carmen González‐Olmedo, Francisco José García‐Verdejo, Antonio Reguera‐Teba, Carmen Rosa‐Garrido, José Antonio López‐López, Leticia Díaz‐Beltrán, Patricia Mena García, Natalia Luque‐Caro, Fernando Gálvez‐Montosa, Ana Laura Ortega‐Granados, María Ruiz‐Sanjuan, Antonio Cózar‐Ibáñez, Juan Sainz, Juan Antonio Marchal, José Camacho, José Pérez delPalacio, Rosario Fernández‐Godino, Caridad Díaz, Pedro Sánchez‐Rovira
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/7b4ca450c8c744ecbc50aea1cb5911cf
Autor:
María G. González-Pedroza, Andrea Regina Tapia Benítez, Saúl A. Navarro-Marchal, Eduardo Martínez-Martínez, Juan A. Marchal, Houria Boulaiz, Raúl A. Morales-Luckie
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nanotechnology is one of the most important and relevant disciplines today due to the specific electrical, optical, magnetic, chemical, mechanical and biomedical properties of nanoparticles. In the present study we demonstrate the efficacy o
Externí odkaz:
https://doaj.org/article/4a53f8d20e204792a5cb87f5596c0af9