Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Juan Segura-Aguilar"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 529-535 (2024)
The positive effect of levodopa in the treatment of Parkinson’s disease, although it is limited in time and has severe side effects, has encouraged the scientific community to look for new drugs that can stop the neurodegenerative process or even r
Externí odkaz:
https://doaj.org/article/ded20040041d47f681f4884efddbdfcf
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1125 (2024)
Recently, a single-neuron degeneration model has been proposed to understand the development of idiopathic Parkinson’s disease based on (i) the extremely slow development of the degenerative process before the onset of motor symptoms and during the
Externí odkaz:
https://doaj.org/article/a2e7e358fa814ef282b4eee715f14532
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 673 (2024)
One of the biggest problems in the treatment of idiopathic Parkinson’s disease is the lack of new drugs that slow its progression. L-Dopa remains the star drug in the treatment of this disease, although it induces severe side effects. The failure o
Externí odkaz:
https://doaj.org/article/db213a531a6741dba54f45bb7c317735
Autor:
Mattace Raso G; Department of Pharmacy, University of Naples, Federioco II, Italy. Electronic address: mattace@unina.it., Avagliano C; Department of Pharmacy, University of Naples, Federioco II, Italy., Calignano A; Department of Pharmacy, University of Naples, Federioco II, Italy.
Publikováno v:
Pharmacological research [Pharmacol Res] 2017 May; Vol. 119, pp. 491-492. Date of Electronic Publication: 2016 Nov 24.
Autor:
Victor Da Silva, Fillipe De Araújo, Cleonice Creusa Dos Santos, Jéssica Souza, Érica Soares, Lucas Matheus Gonçalves De Oliveira, Maria De Fátima Costa, Silvia Costa, Juan Segura-Aguilar, María-Trinidad Herrero
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S49-S50 (2023)
Externí odkaz:
https://doaj.org/article/6c48c51daddd4e0698057420f9e6e5e2
Publikováno v:
Pharmacological research. 119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f85c7faf00b07b586959cadfdabd4c5
https://pubmed.ncbi.nlm.nih.gov/27890814
https://pubmed.ncbi.nlm.nih.gov/27890814
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3094 (2023)
The transition metal characteristics of iron allow it to play a fundamental role in several essential aspects of human life such as the transport of oxygen through hemoglobin or the transport of electrons in the mitochondrial respiratory chain couple
Externí odkaz:
https://doaj.org/article/d8c0c7d09d2c41cea9576978f51c4869
Autor:
Juan Segura-Aguilar, Bengt Mannervik, José Inzunza, Mukesh Varshney, Ivan Nalvarte, Patricia Muñoz
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1861-1866 (2022)
Astrocytes protect neurons by modulating neuronal function and survival. Astrocytes support neurons in several ways. They provide energy through the astrocyte-neuron lactate shuttle, protect neurons from excitotoxicity, and internalize neuronal lipid
Externí odkaz:
https://doaj.org/article/7b1d2a4e60d64753bef746c18035d9e4
Akademický článek
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Autor:
Juan Segura-Aguilar, Bengt Mannervik
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 673 (2023)
Investigations of the effect of antioxidants on idiopathic Parkinson’s disease have been unsuccessful because the preclinical models used to propose these clinical studies do not accurately represent the neurodegenerative process of the disease. Tr
Externí odkaz:
https://doaj.org/article/8245bb6d8123478fab2fbc5999a85e1a