Výsledky vyhledávání - "Juan Colberg"

Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to United Nations Sustainable Development Goal 12

Autor: Frank Roschangar, Jun Li, Yanyan Zhou, Wim Aelterman, Alina Borovika, Juan Colberg, David P. Dickson, Fabrice Gallou, John D. Hayler, Stefan G. Koenig, Michael E. Kopach, Birgit Kosjek, David K. Leahy, Erin O’Brien, Austin G. Smith, Manuel Henry, Jutta Cook, Roger A. Sheldon

Publikováno v: ACS Sustainable Chemistry and Engineering, 10(16)

The large and steadily growing demand for medicines combined with their inherent resource-intensive manufacturing necessitates a relentless push for their sustainable production. Pharmaceutical companies are constantly seeking to perform reliable lif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77447aad8953a5d71e8bac64965dd6a1
https://doi.org/10.1021/acssuschemeng.1c01940

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A Green Chemistry Continuum for a Robust and Sustainable Active Pharmaceutical Ingredient Supply Chain

Autor: Helen F. Sneddon, Frank Roschangar, Sudhir Nambiar, Seth D. Ribe, Jeremy P. Scott, Michael E. Kopach, Scott V. Plummer, Guy R. Humphrey, Juan Colberg, Alina Borovika, Christiana Briddell, Isamir Martinez, Cisco Bee, Stefan G. Koenig

Publikováno v: ACS Sustainable Chemistry & Engineering. 7:16937-16951

In an effort to improve sustainability and reduce the cost of goods for active pharmaceutical ingredients (APIs), pharma companies have partnered on varying portions of their supply chain with cont...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84afb2c0f74a6c1b1faa69c220f1e00b
https://doi.org/10.1021/acssuschemeng.9b02842

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A deeper shade of green: inspiring sustainable drug manufacturing

Autor: John D. Hayler, Frank Roschangar, David K. Leahy, Roger A. Sheldon, Fabrice Gallou, Juan Colberg, John L. Tucker, Peter J. Dunn, Michael E. Kopach, Ingrid Mergelsberg, Stefan G. Koenig, Chris H. Senanayake

Publikováno v: Green Chemistry. 19:281-285

Green and sustainable drug manufacturing go hand in hand with forward-looking visions seeking to balance the long-term sustainability of business, society, and the environment. However, a lack of harmonization among available metrics has inhibited op

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1745a7b0b111d234cc3a302a5808750a
https://doi.org/10.1039/c6gc02901a

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Pharmaceutical Roundtable Study Demonstrates the Value of Continuous Manufacturing in the Design of Greener Processes

Autor: Martin D. Johnson, Peter Poechlauer, Laporte Thomas L, Stefan G. Koenig, Anne O’Kearney-McMullan, Michael Jansen, Elizabeth Fisher, Juan Colberg, Benjamin Martin, Julie B. Manley, Michael Lawler

Publikováno v: Organic Process Research & Development. 17:1472-1478

The American Chemical Society (ACS) Green Chemistry Institute (GCI) Pharmaceutical Roundtable conducted a study to elucidate the value of continuous processing, which had been defined as a key research area for green engineering. In the course of def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8744ce7bf937c2a23d2866bb428c48e
https://doi.org/10.1021/op400245s

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Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation

Autor: Johnson Timothy Allan, Kim Alfonsi, David Austen Perry, Thomas Lee Fevig, Mark H. Stefaniak, Mark A. Nagy, Sandra M. Jennings, H. Peter Kleine, Juan Colberg, Peter J. Dunn, Craig J. Knight

Publikováno v: Green Chem.. 10:31-36

Influencing and improving the environmental performance of a large multi-national pharmaceutical company can be achieved with the help of electronic education tools, backed up by site champions and strong site teams. This paper describes the developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49f76c1c6b89b7fd919ac47e0a94208b
https://doi.org/10.1039/b711717e

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A New and Simplified Process for Preparing N-[4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine and a Telescoped Process for the Synthesis of (1S-cis)-4-(3,4-Dichlorophenol)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine Mandelate: Key Intermediates in the Synthesis of Sertraline Hydrochloride

Autor: Taber Geraldine Patricia, Juan Colberg, Pfisterer David Michael

Publikováno v: Organic Process Research & Development. 8:385-388

N-[4-(3,4-Dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene]methanamine, sertraline imine (3), is an intermediate for the synthesis of Zoloft, sertraline hydrochloride (1). A cleaner, simpler, and more efficient alternative to the Schiff base-media

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5763399c448de248bc1d162de639f30c
https://doi.org/10.1021/op0341465

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