Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Juan‐Li Duan"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Liver sinusoidal endothelial cells (LSECs) play a pivotal role in maintaining liver homeostasis and influencing the pathological processes of various liver diseases. However, neither LSEC-specific hallmark genes nor a LSEC promoter-driven Cr
Externí odkaz:
https://doaj.org/article/39e96225c5d94e58b5561c3e37be29df
Autor:
Zi-Yan Yang, Xian-Chun Yan, Jia-Yu-Lin Zhang, Liang Liang, Chun-Chen Gao, Pei-Ran Zhang, Yuan Liu, Jia-Xing Sun, Bai Ruan, Juan-Li Duan, Ruo-Nan Wang, Xing-Xing Feng, Bo Che, Tian Xiao, Hua Han
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Human cancers induce a chaotic, dysfunctional vasculature that promotes tumor growth and blunts most current therapies; however, the mechanisms underlying the induction of a dysfunctional vasculature have been unclear. Here, we show that split end (S
Externí odkaz:
https://doaj.org/article/bd6ace602e4845dc99347c79490dd45e
Autor:
Ping Song, Juan‐Li Duan, Jian Ding, Jing‐Jing Liu, Zhi‐Qiang Fang, Hao Xu, Zhi‐Wen Li, Wei Du, Ming Xu, Yu‐Wei Ling, Fei He, Kai‐Shan Tao, Lin Wang
Publikováno v:
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Cellular senescence plays a pivotal role in wound healing. At the initiation of liver fibrosis regression, accumulated senescent cells were detected and genes of senescence were upregulated. Flow cytometry combined with single‐cell RNA seq
Externí odkaz:
https://doaj.org/article/282de715011246228dbc7080c8b11c4f
Autor:
Juan-Li Duan, Zi-Yi Zhou, Bai Ruan, Zhi-Qiang Fang, Jian Ding, Jing-Jing Liu, Ping Song, Hao Xu, Chen Xu, Zhen-Sheng Yue, Hua Han, Guo-Rui Dou, Lin Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 6, Pp 1741-1756 (2022)
Background & Aims: Liver sinusoidal endothelial cells (SECs) promote the proliferation of hepatocytes during liver regeneration. However, the specific subset of SECs and its mechanisms during the process remain unclear. In this study, we investigated
Externí odkaz:
https://doaj.org/article/b27444dfc94d4ffca32566f095d14851
Autor:
Jia-Xing Sun, Guo-Rui Dou, Zi-Yan Yang, Liang Liang, Juan-Li Duan, Bai Ruan, Man-Hong Li, Tian-Fang Chang, Xin-Yuan Xu, Juan-Juan Chen, Yu-Sheng Wang, Xian-Chun Yan, Hua Han
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 554-566 (2021)
After angiogenesis-activated embryonic and early postnatal vascularization, endothelial cells (ECs) in most tissues enter a quiescent state necessary for proper tissue perfusion and EC functions. Notch signaling is essential for maintaining EC quiesc
Externí odkaz:
https://doaj.org/article/6b355598f6fc466e98e22b4d43c3b38d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Tissue-specific endothelial cells are more than simply a barrier lining capillaries and are proved to be capable of remarkable plasticity to become active collagen matrix-producing myofibroblasts (MFs) in solid organs with fibrosis. Liver sinusoidal
Externí odkaz:
https://doaj.org/article/168b357a9b45476b939d838ca462ff0d
Publikováno v:
Journal of Bio-X Research, Vol 1, Iss 2, Pp 95-104 (2018)
Abstract. This review aims to compile recent advances regarding the significance of Notch signaling in different types of intrahepatic cells during liver injury and repair. The functions of Notch signaling in regulating cell development, fate decisio
Externí odkaz:
https://doaj.org/article/0d0e9edba8c3473488ab53ba6f44b72e
Autor:
Xian‐Chun Yan, Jing Cao, Liang Liang, Li Wang, Fang Gao, Zi‐Yan Yang, Juan‐Li Duan, Tian‐Fang Chang, San‐Ming Deng, Yuan Liu, Guo‐Rui Dou, Jian Zhang, Qi‐Jun Zheng, Ping Zhang, Hua Han
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
BackgroundEndothelial cells (ECs) form blood vessels through angiogenesis that is regulated by coordination of vascular endothelial growth factor (VEGF), Notch, transforming growth factor β, and other signals, but the detailed molecular mechanisms r
Externí odkaz:
https://doaj.org/article/eef58ee14aa048468431e50968e09608
Autor:
Jian Ding, Ming Xu, Wei Du, Zhi-Qiang Fang, Hao Xu, Jing-Jing Liu, Ping Song, Chen Xu, Zhi-Wen Li, Zhen-Sheng Yue, Yu-Wei Ling, Juan-Li Duan, Kai-Shan Tao, Fei He, Lin Wang
Publikováno v:
International Journal of Biological Sciences. 19:1941-1954
Autor:
Juan-Li Duan, Jing-Jing Liu, Bai Ruan, Jian Ding, Zhi-Qiang Fang, Hao Xu, Ping Song, Chen Xu, Zhi-Wen Li, Wei Du, Ming Xu, Yu-Wei Ling, Fei He, Lin Wang
Publikováno v:
Nature Aging. 3:258-274