NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model

Autor: Shu-ichi Okamoto, Olga Prikhodko, Juan Pina-Crespo, Anthony Adame, Scott R. McKercher, Laurence M. Brill, Nobuki Nakanishi, Chang-ki Oh, Tomohiro Nakamura, Eliezer Masliah, Stuart A. Lipton

Publikováno v: Neurobiology of Disease, Vol 127, Iss , Pp 390-397 (2019)

Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by heterozygous mutations in the TSC1 or TSC2 gene. TSC is often associated with neurological, cognitive, and behavioral deficits. TSC patients also express co-morbidity with anxiety a

Externí odkaz: https://doaj.org/article/a572bd40338d4b15b09c31e72f6e65cb

Optimizing design in open channel

Autor: Martin Hidalgo, Juan Pina, Dante Bragoni

Publikováno v: Environmental Hydraulics-Theoretical, Experimental and Computational Solutions: Proceedings of the International Workshop on Environmental Hydraulics, IWEH09, 29 & 30 October 2009, Valencia, Spain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d8de8af9e7e2615bc771588d60e2e0a
https://doi.org/10.1201/b10999-7

Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment.

Autor: Lu-Lin Jiang¹, Bing Zhu¹, Yingjun Zhao¹, Xiaoguang Li¹, Tongfei Liu¹, Juan Pina-Crespo¹, Lisa Zhou¹, Wenxi Xu², Rodriguez, Maria J.^3,4, Haiyang Yu⁵, Cleveland, Don W.^3,5,6, Ravits, John^3,4, Da Cruz, Sandrine⁵, Tao Long², Dongxian Zhang¹, Huang, Timothy Y.¹, Huaxi Xu¹ xuh@sbpdiscovery.org, Jiang, Lu-Lin¹ (AUTHOR), Zhu, Bing¹ (AUTHOR), Zhao, Yingjun¹ (AUTHOR)

Publikováno v: Journal of Clinical Investigation. Aug2019, Vol. 129 Issue 8, p3103-3120. 18p.