Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ju-Xian Wang"'
Autor:
Jian Xu, Ju-xian Wang, Jin-ming Zhou, Chang-liang Xu, Bin Huang, Yun Xing, Bin Wang, Rui Luo, Yu-cheng Wang, Xue-fu You, Yu Lu, Li-yan Yu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Protein kinase B (PknB) is one of the Mycobacterium tuberculosis serine/threonine protein kinases and has an essential role in sustaining mycobacterial growth. Here, we identified and characterized a novel small molecule compound named IMB-Y
Externí odkaz:
https://doaj.org/article/a22e2ae045844aef9db204f3b1fa9c74
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 17256-17278 (2014)
A series of chalcones a1–20 bearing a 4-OMe groups on the A-ring were initially synthesized and their anticancer activities towards HepG2 cells evaluated. Subsequently, a series of chalcones b1–42 bearing methoxy groups at the 2' and 6'-positions
Externí odkaz:
https://doaj.org/article/9b92b063732a47c4bc0346718259895d
Autor:
Rong-Guang Shao, Shi-Ying Cai, Chang-Liang Xu, Ju-Xian Wang, Xiao-Guang Bai, Hong-Wei He, Hong-Tao Liu, Yu-Cheng Wang
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 6883-6897 (2013)
The apical sodium-dependent bile salt transporter (ASBT) plays a pivotal role in maintaining bile acid homeostasis. Inhibition of ASBT would reduce bile acid pool size and lower cholesterol levels. In this report, a series of novel arylsulfonylaminob
Externí odkaz:
https://doaj.org/article/74be97d8ff37447ca2417e02c84560b7
Autor:
Ju-Xian Wang, Chao Feng
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 12, Pp o1287-o1287 (2014)
In the title molecule, C13H14N2O2, the dihedral angle between the pyrazole and benzene ring mean planes is 76.06 (11)°, and the conformation of the ethyl side chain is anti [C—O—C—C = −175.4 (3)°]. In the crystal, the only directional inter
Externí odkaz:
https://doaj.org/article/cbac0844775c4ad781b7d745729b9f9f
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 8, Pp o843-o843 (2014)
The title compound, C14H28N2O5S, was synthesized by the reaction of 2-[(methylsulfanyl)methyl]oxirane with di-tert-butyl oxalate in hydrazine hydrate. In the crystal, molecules are linked by N—H...O and O—H...O hydrogen bonds into supramolecular
Externí odkaz:
https://doaj.org/article/0c006ef8c3ae4c68bc2b686d8c428c16
Autor:
Xiao-Guang Bai, Ju-Xian Wang
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 6, Pp o674-o674 (2014)
The title compound, C18H30N2O5S, was synthesized by the reaction of tert-butyl 2-(isobutylamino)ethylcarbamate with p-methoxyphenylsulfonyl chloride. In the molecule, two intramolecular C—H...O hydrogen bonds are observed. In the crystal, molecules
Externí odkaz:
https://doaj.org/article/ac1bd47952ac4be2ac4ea46731998c69
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 6, Pp o1677-o1677 (2012)
In the molecule of the title compound, C21H18N4O3, the fused pyrrolo[3,4-c]pyrazole ring system is approximately planar [maximum deviation = 0.0486 (16) Å] and forms dihedral angles of 87.21 (8) and 35.46 (7)° with the phenyl rings. In the crystal,
Externí odkaz:
https://doaj.org/article/49ba37b210d54c71bf6b2c6ba8525529
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 1, Pp o4-o4 (2012)
The molecular structure of the title compound, C10H8Cl2O3, exists in a cis-enol form, which is stabilized by a strong intramolecular O—H...O hydrogen bond. In the crystal, C—H...O interactions generate zigzag chains along the c axis which are, in
Externí odkaz:
https://doaj.org/article/593d2b3111054799b065928bbd65cf36
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 5, Pp o1150-o1150 (2011)
The asymmetric unit of the title compound, C13H20N4O4, contains two crystallographically independent molecules in which the dihedral angles between the fused pyrrole and pyrazole rings are 5.06 (8) and 1.12 (8)°. In the crystal, molecules are linked
Externí odkaz:
https://doaj.org/article/a9afc58b80044b11928967be195192ed
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 5, Pp o1103-o1103 (2011)
In the cation of the title compound, C18H20ClN4O3S+·Cl−, the tetrahydropyridinium ring assumes a half-chair conformation. The dihedral angle between the pyrazole ring and the naphthalene ring system is 75.19 (6)°. In the crystal, ions are linked
Externí odkaz:
https://doaj.org/article/2952bb062c7d4f12b42e0e2fa353a315