Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Ju-Seog L"'
Autor:
Yun Seong Jeong, Young-Gyu Eun, Sung Hwan Lee, Sang-Hee Kang, Sun Young Yim, Eui Hyun Kim, Joo Kyung Noh, Bo Hwa Sohn, Seon Rang Woo, Moonkyoo Kong, Deok Hwa Nam, Hee-Jin Jang, Hyun-Sung Lee, Shumei Song, Sang Cheul Oh, Jeeyun Lee, Jaffer A. Ajani, Ju-Seog Lee
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-17 (2023)
Abstract Gastric adenocarcinoma (GAC) is a lethal disease characterized by genomic and clinical heterogeneity. By integrating 8 previously established genomic signatures for GAC subtypes, we identified 6 clinically and molecularly distinct genomic co
Externí odkaz:
https://doaj.org/article/ccfad52390c4482ca6467186cf9c2361
Autor:
Rui Chen, Elaina Coleborn, Chintan Bhavsar, Yue Wang, Louisa Alim, Andrew N. Wilkinson, Michelle A. Tran, Gowri Irgam, Sharat Atluri, Kiefer Wong, Jae-Jun Shim, Siddharth Adityan, Ju-Seog Lee, Willem W. Overwijk, Raymond Steptoe, Da Yang, Sherry Y. Wu
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100725- (2023)
Immunotherapies have emerged as promising strategies for cancer treatment. However, existing immunotherapies have poor activity in high-grade serous ovarian cancer (HGSC) due to the immunosuppressive tumor microenvironment and the associated low tumo
Externí odkaz:
https://doaj.org/article/88542394fd9f4c9a9f44ff43addb21fd
Autor:
Masashi Fujita, Mei-Ju May Chen, Doris Rieko Siwak, Shota Sasagawa, Ayako Oosawa-Tatsuguchi, Koji Arihiro, Atsushi Ono, Ryoichi Miura, Kazuhiro Maejima, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuaki Chayama, Ju-Seog Lee, Yiling Lu, Gordon B. Mills, Han Liang, Satoshi S. Nishizuka, Hidewaki Nakagawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The molecular heterogeneity of primary liver cancer remains to be characterised. Here, the authors perform multi-omics analysis of 259 primary liver cancer tissues and identify three distinct molecular subtypes.
Externí odkaz:
https://doaj.org/article/2b8bfa4d2fb8409dadad46cf1b22157e
Autor:
Sung Hwan Lee, Yun Seong Jeong, Sunyoung Lee, Bo Hwa Sohn, Ho Kyoung Hwang, Gi Hong Choi, Chang Moo Kang, Jin Sub Choi, Woo Jung Lee, Jae‐Ho Cheong, Hee Jin Jang, Ahmed Kaseb, Lewis Roberts, Sun Young Yim, Yun Shin Chun, Ju‐Seog Lee
Publikováno v:
Cancer Communications, Vol 42, Iss 2, Pp 179-183 (2022)
Externí odkaz:
https://doaj.org/article/91ef7777a8c54618b418d09773ba857d
Autor:
Min‐Kyue Shin, Jungmin Kim, Dachan Kim, Sung Hwan Lee, Ji‐Hyun Shin, Yun Seong Jeong, Bo Hwa Sohn, Jimin Kim, Seong‐Ryong Kim, Jaffer A. Ajani, Ju‐Seog Lee, Jae‐Ho Cheong
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/9bfab09c645a4f4e9d6547ce82320e3e
Autor:
Ju-Seog Lee, Sung Uk Bae, Hye Won Lee, Incheol Seo, Sang Jun Byun, Jee Young Park, Hyeonji Min, Sung Hwan Lee, Shin Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Neoadjuvant chemoradiation therapy (CRT) is a widely used preoperative treatment strategy for locally advanced rectal cancer (LARC). However, a few studies have evaluated the molecular changes caused by neoadjuvant CRT in these cancer tiss
Externí odkaz:
https://doaj.org/article/76e097c2c7c2487b91abda284b224661
Autor:
Gena Lee, Yun Seong Jeong, Do Won Kim, Min Jun Kwak, Jiwon Koh, Eun Wook Joo, Ju-Seog Lee, Susie Kah, Yeong-Eun Sim, Sun Young Yim
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 11, Pp 1-12 (2018)
Cancer: Spotlighting hidden cancer-causing genes Mutation of a gene with no clear role in tumor development triggers a cascade of reactions that can cause liver cancer. Recent genome-wide analyses searching for genes connected to development of hepat
Externí odkaz:
https://doaj.org/article/9cb31fbad80d4cf9ad33d769870682e4
Autor:
Myoung-Hee Kang, Hyunji Choi, Masanobu Oshima, Jae-Ho Cheong, Seokho Kim, Jung Hoon Lee, Young Soo Park, Hueng-Sik Choi, Mi-Na Kweon, Chan-Gi Pack, Ju-Seog Lee, Gordon B. Mills, Seung-Jae Myung, Yun-Yong Park
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Very little is known regarding the molecular mechanisms involved in gastric cancer development. Here the authors show estrogen-related receptor gamma (ESRRG) is a tumor suppressor in gastric cancer and suggest the mechanism of this tumor suppression
Externí odkaz:
https://doaj.org/article/973b51c8851d4d10916c207ff982e196
Autor:
Sang Cheul Oh, Bo Hwa Sohn, Jae-Ho Cheong, Sang-Bae Kim, Jae Eun Lee, Ki Cheong Park, Sang Ho Lee, Jong-Lyul Park, Yun-Yong Park, Hyun-Sung Lee, Hee-Jin Jang, Eun Sung Park, Sang-Cheol Kim, Jeonghoon Heo, In-Sun Chu, You-Jin Jang, Young-Jae Mok, WonKyung Jung, Baek-Hui Kim, Aeree Kim, Jae Yong Cho, Jae Yun Lim, Yuki Hayashi, Shumei Song, Elena Elimova, Jeannelyn S. Estralla, Jeffrey H. Lee, Manoop S. Bhutani, Yiling Lu, Wenbin Liu, Jeeyun Lee, Won Ki Kang, Sung Kim, Sung Hoon Noh, Gordon B. Mills, Seon-Young Kim, Jaffer A. Ajani, Ju-Seog Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The prognosis and treatment of gastric cancer is complicated by heterogeneity. Here, the authors reveal two molecular subtypes, the mesenchymal subtype associated with poor survival and chemoresistance, and the epithelial phenotype associated with be
Externí odkaz:
https://doaj.org/article/cb4f389472124edeb3126b20dcd9ed15
Autor:
Ji-Hye Ahn, Hyun-Sung Lee, Ju-Seog Lee, Yeon-Su Lee, Jong-Lyul Park, Seon-Young Kim, Jung-Ah Hwang, Nawapol Kunkeaw, Sung Yun Jung, Tae Jin Kim, Kwang-Soo Lee, Sung Ho Jeon, Inhan Lee, Betty H. Johnson, Jung-Hye Choi, Yong Sun Lee
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Ovarian cancers often display elevated TGF-β signaling but repressed miRNA expression. Here the authors identify that non-coding RNA nc886 expression is induced by TGF-β, which then binds to DICER and impairs miRNA maturation.
Externí odkaz:
https://doaj.org/article/1fef08d16d4f4920ab3eed8776cd77e0