Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ju-Hua Ni"'
Autor:
Hong-Yu Zhang, Yan-Yan Gu, Zeng-Gang Li, Yu-Hong Jia, Lan Yuan, Shu-Yan Li, Guo-Shun An, Ju-Hua Ni, Hong-Ti Jia
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 6, Iss 6, Pp 802-812 (2004)
8-Chloro-adenosine (8-CI-Ado) is a potent chemotherapeutic agent whose cytotoxicity in a variety of tumor cell lines has been widely investigated. However, the molecular mechanisms are uncertain. In this study, we found that exposure of human lung ca
Externí odkaz:
https://doaj.org/article/0a978eaca6cc4dcf87af4fe7f2b7052a
Autor:
Shu-Yan Li, Tong-Jia Zhang, Hong-Ti Jia, Jun-Yi Wang, Guo-Shun An, Jing-Jing Liang, Ju-Hua Ni
Publikováno v:
Current Topics in Medicinal Chemistry. 20:835-846
Background: Although the involvement of individual microRNA and lncRNA in the regulation of p21 expression has largely been evidenced, less is known about the roles of functional interactions between miRNAs and lncRNAs in p21 expression. Our previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f454fa0b5516e6a73d4a0facb45b734
https://doi.org/10.2174/1568026620666200306102713
https://doi.org/10.2174/1568026620666200306102713
Publikováno v:
The Journal of Biological Chemistry
Mitochondrial biogenesis and energy metabolism are essential for regulating the inflammatory state of monocytes. This state is partially controlled by peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), a coactivator that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f5a737a61216099b15e0cf529d0de75
http://europepmc.org/articles/PMC8406003
http://europepmc.org/articles/PMC8406003
Publikováno v:
The American journal of the medical sciences. 360(6)
Background Lung squamous cell carcinoma (LUSC) accounts up for approximately 30% of all lung cancers with a high mortality. The study was aimed at finding genes critical in the diagnosis and prognosis of LUSC. Materials and Methods The differentially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b09e7231dc8f7af4b99da6814dfea8
https://pubmed.ncbi.nlm.nih.gov/33012486
https://pubmed.ncbi.nlm.nih.gov/33012486
Autor:
Hong-Ti Jia, Ju-Hua Ni, Shu-Yan Li, Xian-Hui Wang, Yao Lu, Ji-Xiang Cao, Guo-Shun An, Ya-Qiong Jin, Jing-Jing Liang
Publikováno v:
Biochemical and Biophysical Research Communications. 478:676-682
MicroRNAs (miRNAs) are potent post-transcriptional regulators of gene expression and play roles in DNA damage response (DDR). PLK1 is identified as a modulator of DNA damage checkpoint. Although down-regulation of PLK1 by certain microRNAs has been r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e06ab0a202f6f6aafebdf95928ade14
https://doi.org/10.1016/j.bbrc.2016.08.006
https://doi.org/10.1016/j.bbrc.2016.08.006
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 6; Pages: 1587
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1587 (2018)
International Journal of Molecular Sciences; Volume 19; Issue 6; Pages: 1587
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1587 (2018)
Human lung cancer H1299 (p53-null) cells often display enhanced susceptibility to chemotherapeutics comparing to A549 (p53-wt) cells. However, little is known regarding to the association of DNA damage-response (DDR) pathway heterogeneity with drug s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5c7aa046c782c6a8579dfe8a09b57d
https://pubmed.ncbi.nlm.nih.gov/29843366
https://pubmed.ncbi.nlm.nih.gov/29843366
Autor:
Gang Li, Hong-Ti Jia, Ji-Xiang Cao, Ling Liu, Guo-Shun An, Ju-Hua Ni, Jun-Juan Qi, Shu-Yan Li
Publikováno v:
Molecular and Cellular Biochemistry. 399:179-188
The p53R2 gene encoding a small subunit of the ribonucleotide reductase has been identified as a p53-inducible gene. Although this gene is discovered as a target for p53 family proteins, the mechanism underlying p53R2 induction by DNA damage in p53-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0388240f1a6e35b473eee990a2163f
https://doi.org/10.1007/s11010-014-2244-7
https://doi.org/10.1007/s11010-014-2244-7
Autor:
Jun-Juan Qi, Ju-Hua Ni, Chao Du, Shu-Yan Li, Guo-Shun An, Hong-Ti Jia, Ya-Qiong Jin, Zhen-Xing Ji
Publikováno v:
Molecules and Cells. 34:133-142
MyoD and myogenin (Myog) recognize sets of distinct but overlapping target genes and play different roles in skeletal muscle differentiation. MyoD is sufficient for near-full expression of early targets, while Myog can only partially enhance expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c34fa3d6f5cb4eda1abfeb38e60c39
https://doi.org/10.1007/s10059-012-2286-1
https://doi.org/10.1007/s10059-012-2286-1
Publikováno v:
Biochemical Pharmacology. 77:433-443
8-Chloro-cAMP and 8-chloro-adenosine (8-Cl-Ado) are known to inhibit proliferation of cancer cells by converting 8-Cl-Ado into an ATP analog, 8-chloro-ATP (8-Cl-ATP). Because type II topoisomerases (Topo II) are ATP-dependent, we infer that 8-Cl-Ado
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a62c063824027b9a57a1fd15f9f220a
https://doi.org/10.1016/j.bcp.2008.10.022
https://doi.org/10.1016/j.bcp.2008.10.022
Publikováno v:
Biochemical Pharmacology. 72:541-550
A key feature of actin is its ability to bind and hydrolyze ATP. 8-Chloro-adenosine (8-Cl-Ado), which can be phosphorylated to the moiety of 8-Cl-ATP in living cells, inhibits tumor cell proliferation. Therefore we tested the hypothesis that 8-Cl-Ado
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e059c45d7cfebbb63aba8ea30a7f99a
https://doi.org/10.1016/j.bcp.2006.05.026
https://doi.org/10.1016/j.bcp.2006.05.026