Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Ju Zhu"'
Publikováno v:
BMC Chemistry, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract As an essential marker of cancer treatment, PARP-1 inhibitors could effectively kill tumor cells through a mechanism known as synthetic lethality and are used to treat a variety of cancers. In order to explore novel PARP-1 inhibitors, a seri
Externí odkaz:
https://doaj.org/article/db53e270e2de483ea50fed1ed2e39fe2
Autor:
Chao Hu, Meiying Shen, Xiaojian Han, Qian Chen, Luo Li, Siyin Chen, Jing Zhang, Fengxia Gao, Wang Wang, Yingming Wang, Tingting Li, Shenglong Li, Jingjing Huang, Jianwei Wang, Ju Zhu, Dan Chen, Qingchen Wu, Kun Tao, Da Pang, Aishun Jin
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 216-229 (2022)
Despite the growing knowledge of T cell responses in COVID-19 patients, there is a lack of detailed characterizations for T cell-antigen interactions and T cell functions. Here, with a predicted peptide library from SARS-CoV-2 S and N proteins, we fo
Externí odkaz:
https://doaj.org/article/dbbc61accec0439f8144016538c03889
Publikováno v:
The Astrophysical Journal Supplement Series, Vol 265, Iss 1, p 18 (2023)
We present low-resolution optical spectra and classifications of 92 blue objects with mid-infrared excesses in the Large Magellanic Cloud. The majority of these objects were selected with the criteria of U − B < 0 and V < 17 from the potential youn
Externí odkaz:
https://doaj.org/article/2b6e5994da794efe9d6b09288886ee02
Autor:
Jian Hu, Wei Tian, Ruolan Zhou, Yuefan Zhang, Jiaguo Lv, Ju Zhu, Xin Chen, Xianhua Pan, Canhui Zheng
Publikováno v:
Journal of Saudi Chemical Society, Vol 23, Iss 3, Pp 255-262 (2019)
Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is an important enzyme response for the metabolism or detoxification of toxic aldehydes, in particular acetaldehyde and 4-hydroxynonenal (4-HNE), which were important risk factors for acute alcoholism an
Externí odkaz:
https://doaj.org/article/9ebfcbea0ee74adf874c32f43fa7eebe
Autor:
Ling Zhang, Yunlong Song, Jingjing Huang, Jia Liu, Wenwen Zhu, Youjun Zhou, Jiaguo Lv, Canhui Zheng, Ju Zhu
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 10173-10184 (2015)
A series of 1,4-disubstituted-3,4-dihydroisoquinoline derivatives designed as tubulin polymerization inhibitors were synthesized. Their cytotoxic activities against the CEM leukemia cell line were evaluated. Most of them displayed moderate cytotoxic
Externí odkaz:
https://doaj.org/article/0597fa695e434544b0c43c7538516fc9
Publikováno v:
Journal of Diabetes Research, Vol 2017 (2017)
Impaired glucose regulation (IGR) is the prestate of diabetes; about 1/3 of IGR patients will develop to diabetes finally. In this study, we investigated the serum tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) levels in peripheral neu
Externí odkaz:
https://doaj.org/article/e53691615fdc4352aa00d4e3d6bea64f
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 4, Pp o1111-o1111 (2012)
The asymmetric unit of the title compound, C12H12N2O3, contains two molecules in which the benzene and isoxazole rings are almost coplanar, the dihedral angles between their mean planes being 1.76 (9) and 5.85 (8)°. The two molecules interact with e
Externí odkaz:
https://doaj.org/article/09fb35d2ab0b4feeadb9085a3fc575c1
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 3, Pp o901-o901 (2012)
In the title compound, C13H15N3O3, the dihedral angle between the benzene and pyrazole rings is 7.7 (1)° and the O—C—C—N torsion angle of the side chain is 74.1 (2)°. In the crystal, molecules are linked by O—H...O, N—H...O and N—H...N
Externí odkaz:
https://doaj.org/article/203ec79bdcc44933aa3405af176c6d76
Akademický článek
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Publikováno v:
Medical Ultrasonography. 2023, Vol. 25 Issue 1, p22-28. 7p.