Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ju Yuel, Baek"'
Autor:
Felix Broecker, Jonas Hanske, Christopher E. Martin, Ju Yuel Baek, Annette Wahlbrink, Felix Wojcik, Laura Hartmann, Christoph Rademacher, Chakkumkal Anish, Peter H. Seeberger
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Immunologically-active glycans are promising vaccine candidates but can be difficult to synthesize. Here, the authors show that pentavalent display of a minimal disaccharde epitope on a chemical scaffold can mimic a native C. difficileglycan antigen,
Externí odkaz:
https://doaj.org/article/14c948723fd84a6ab537dce51dcba054
Autor:
Someswara Rao, Sanapala, Bruna M S, Seco, Ju Yuel, Baek, Shahid I, Awan, Claney L, Pereira, Peter H, Seeberger
Publikováno v:
Chemical Science
Streptococcus pneumoniae 19A (ST19A) and 19F (ST19F) are among the prevalent serotypes causing pneumococcal disease worldwide even after introduction of a 13-valent pneumococcal conjugate vaccine (PCV13). Synthetic glycoconjugate vaccines have define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e20e99b4454436f57d11d3e022c2306
https://pubmed.ncbi.nlm.nih.gov/34123020
https://pubmed.ncbi.nlm.nih.gov/34123020
Autor:
Peter H. Seeberger, Dominea C. K. Rathwell, Claney L. Pereira, Andreas Geissner, David Meierhofer, Ju Yuel Baek
Publikováno v:
Chemical Science
The first glycoconjugate vaccine using isolated glycans was licensed to protect children from Haemophilus influenzae serotype b (Hib) infections. Subsequently, the first semisynthetic glycoconjugate vaccine using a mixture of antigens derived by poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d00f96d6a2b539d7ab7d1f31a3bf75d
https://doi.org/10.1039/c7sc04521b
https://doi.org/10.1039/c7sc04521b
Autor:
Someswara Rao Sanapala, Bruna M. S. Seco, Ju Yuel Baek, Shahid I. Awan, Peter H. Seeberger, Claney L. Pereira
Publikováno v:
Chemical Science
Streptococcus pneumoniae 19A (ST19A) and 19F (ST19F) are among the prevalent serotypes causing pneumococcal disease worldwide even after introduction of a 13-valent pneumococcal conjugate vaccine (PCV13). Synthetic glycoconjugate vaccines have define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86eaa38723fcaedc7c56b17ce74fca18
https://hdl.handle.net/21.11116/0000-0006-CF90-E21.11116/0000-0006-CF92-C
https://hdl.handle.net/21.11116/0000-0006-CF90-E21.11116/0000-0006-CF92-C
Publikováno v:
The Journal of Organic Chemistry. 81:11372-11383
An efficient direct phthalic anhydride-mediated one-pot glycosylation method employing anomeric hydroxy arabinofuranose as glycosyl donor and triflic anhydride as activating agent has been developed. This method afforded the desired di- and oligoarab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988bc8e28f7740b3a93f6adc29e96fb6
https://doi.org/10.1021/acs.joc.6b01723
https://doi.org/10.1021/acs.joc.6b01723
Autor:
Ju Yuel Baek, Se Jin Myung, Dominea C. K. Rathwell, Mi Young Kim, Hea-Won Kwon, Kwan Soo Kim, Jung Jun Park, Peter H. Seeberger, Heung Bae Jeon
Publikováno v:
Tetrahedron. 71:5315-5320
Glucosylations and galactosylations of various acceptors with donors possessing an electron-withdrawing benzylsulfonyl, benzoyl, or acetyl group at the O-3 or O-4 position were performed. A β-directing effect by the benzylsulfonyl group at O-3 of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::653fbb19dbcdf34b411c11056b17a559
https://doi.org/10.1016/j.tet.2015.06.014
https://doi.org/10.1016/j.tet.2015.06.014
Autor:
Jin Won Cho, Kwang Min Choe, Jürgen Roth, Kwan Soo Kim, Ye Jin Jy, Si Hyoung Park, Ju Yuel Baek, Su-Jin Park
Publikováno v:
Cellular and Molecular Life Sciences. 68:3377-3384
Modification of nuclear and cytosolic proteins by O-linked N-acetylglucosamine (O-GlcNAcylation) is ubiquitous in cells. The in vivo function of the protein O-GlcNAcylation, however, is not well understood. Here, we manipulated the cellular O-GlcNAcy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fcfa472e8966af248406ec3d1ff6e0
https://doi.org/10.1007/s00018-011-0640-7
https://doi.org/10.1007/s00018-011-0640-7
Publikováno v:
Tetrahedron Letters. 51:6250-6254
An efficient and direct one-pot glycosylation method using anomeric hydroxy sugars as glycosyl donors, employing 3-fluorophthalic anhydride and triflic anhydride as activating agents, has been developed. The present glycosylation utilizing 3-fluoroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0d6b1420dd0cf66aaff9b3fc993b843
https://doi.org/10.1016/j.tetlet.2010.09.064
https://doi.org/10.1016/j.tetlet.2010.09.064
Autor:
Gha-Seung Park, Han Kyong Kim, Moon Sub Lee, Kwan Soo Kim, Young-Kil Chang, Jaeheon Lee, Chul Hyun Park, Ju Yuel Baek, Gwan-Sun Lee, Bo-Young Lee
Publikováno v:
Tetrahedron. 66:5687-5691
An efficient large-scale synthesis of gemcitabine was achieved without chromatography or fractional crystallization. The key steps include stereospecific conversion of a novel β-ribofuranosyl phosphate into a highly crystalline α-ribofuranosyl brom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c5a6d9088d5a753f9d563e40731173
https://doi.org/10.1016/j.tet.2010.05.039
https://doi.org/10.1016/j.tet.2010.05.039
Publikováno v:
Journal of the American Chemical Society. 131:17705-17713
Mannosylations of various acceptors with donors possessing an electron-withdrawing o-trifluoromethylbenzenesulfonyl, benzylsulfonyl, p-nitrobenzoyl, benzoyl, or acetyl group at O-3, O-4, or O-6 positions were found to be beta-selective except when do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5eefdf784344950eea3bcb8794dbd9e
https://doi.org/10.1021/ja907252u
https://doi.org/10.1021/ja907252u