Strategies to Overcome Obstacles to Successful Immunotherapy of Melanoma

Autor: Serena Lolli, Franco Pandolfi, Rossella Cianci, Tj Haggerty, Jt Kurnick, Ee Newton, La Boyle, Is Dunn

Publikováno v: Scopus-Elsevier

The immunogenicity of malignant melanomas has been recognized by the observed recruitment of tumor-specific cytotoxic T-cells (CTL), leading to the identification of several melanoma associated antigen (MAA). However, numerous strategies to treat mel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d28480340d36c900f64463121a9207a
https://doi.org/10.1177/039463200802100302

Factor XIII A is synthesized and expressed on the surface of U937 cells and alveolar macrophages

Autor: RL Kradin, GW Lynch, JT Kurnick, M Erikson, RB Colvin, J McDonagh

Publikováno v: Blood. 69(3)

Factor XIII A subunit was detected in U937 cells and human alveolar macrophages by immunohistology and Western blotting. U937 cells synthesize factor XIII A subunit de novo under serum-free, platelet- free conditions, as indicated by 35S-methionine l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b92f5d5206bbc723bc256dd997dcb68
https://pubmed.ncbi.nlm.nih.gov/2880614

Assembly of Biologically Functional Structures by Nucleic Acid Templating: Implementation of a Strategy to Overcome Inhibition by Template Excess.

Autor: Lawler MM; TriBiotica LLC, 100 Cummings Center, Suite 424-J, Beverly, MA 01915, USA., Kurnick JT; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Fagundes St Pierre L; TriBiotica LLC, 100 Cummings Center, Suite 424-J, Beverly, MA 01915, USA., Newton EE; TriBiotica LLC, 100 Cummings Center, Suite 424-J, Beverly, MA 01915, USA., Rose LB; TriBiotica LLC, 100 Cummings Center, Suite 424-J, Beverly, MA 01915, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Dunn IS; TriBiotica LLC, 100 Cummings Center, Suite 424-J, Beverly, MA 01915, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 12; Vol. 27 (20). Date of Electronic Publication: 2022 Oct 12.

Heat shock protein-90 inhibitors enhance antigen expression on melanomas and increase T cell recognition of tumor cells.

Autor: Haggerty TJ; CytoCure LLC, Suite 430C, 100 Cummings Center, Beverly, MA, United States of America; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America., Dunn IS; CytoCure LLC, Suite 430C, 100 Cummings Center, Beverly, MA, United States of America., Rose LB; CytoCure LLC, Suite 430C, 100 Cummings Center, Beverly, MA, United States of America., Newton EE; CytoCure LLC, Suite 430C, 100 Cummings Center, Beverly, MA, United States of America., Pandolfi F; Department of Internal Medicine, Catholic University, Rome, Italy., Kurnick JT; CytoCure LLC, Suite 430C, 100 Cummings Center, Beverly, MA, United States of America; Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Dec 12; Vol. 9 (12), pp. e114506. Date of Electronic Publication: 2014 Dec 12 (Print Publication: 2014).

Skewed T-cell receptor repertoire: more than a marker of malignancy, a tool to dissect the immunopathology of inflammatory diseases.

Autor: Pandolfi F, Cianci R, Casciano F, Pagliari D, De Pasquale T, Landolfi R, Di Sante G, Kurnick JT, Ria F

Publikováno v: Journal of biological regulators and homeostatic agents [J Biol Regul Homeost Agents] 2011 Apr-Jun; Vol. 25 (2), pp. 153-61.