An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq.

Autor: Kolliari-Turner A; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK.; Centre for Stress and Age-Related Disease, University of Brighton, Brighton, UK., Lima G; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK.; Muscle Research, Murdoch Children's Research Institute, Parkville, VIC, Australia.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Wang G; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK.; Centre for Regenerative Medicine and Devices, University of Brighton, Brighton, UK., Malinsky FR; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK., Karanikolou A; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK., Eichhorn G; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK.; Environmental Extremes Laboratory, University of Brighton, Eastbourne, UK., Tanisawa K; Faculty of Sport Sciences, Waseda University, Tokorozawa, Japan., Ospina-Betancurt J; Faculty of Education, University of Valladolid, Soria, Spain., Hamilton B; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK.; Centre for Stress and Age-Related Disease, University of Brighton, Brighton, UK.; The Gender Identity Clinic, Tavistock and Portman NHS Foundation Trust, London, UK., Kumi PYO; Centre for Sports and Exercise Medicine, William Harvey Research Institute, Queen Mary University of London, London, UK., Shurlock J; Somerset NHS Foundation Trust, Taunton, UK., Skiadas V; University Hospital Southampton NHS Foundation Trust, Southampton, UK., Twycross-Lewis R; School of Engineering and Materials Science, Queen Mary University of London, London, UK.; St Mary's University, Twickenham, London, UK., Kilduff L; Applied Sports, Technology, Exercise, and Medicine Research Centre (A-STEM), Faculty of Science and Engineering, Swansea University, Swansea, Wales., Martin RP; Department of Biophysics, Federal University of Sao Paulo, Sao Paulo, Brazil.; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ash GI; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Center for Medical Informatics, Yale University, New Haven, CT, USA., Potter C; MGI, Riga, Latvia., Guppy FM; Centre for Stress and Age-Related Disease, University of Brighton, Brighton, UK.; Institute for Life and Earth Sciences, School of Energy, Geoscience, Infrastructure and Society, Heriot-Watt University, Edinburgh, UK., Seto JT; Muscle Research, Murdoch Children's Research Institute, Parkville, VIC, Australia.; Department of Paediatrics, University of Melbourne, Parkville, VIC, Australia., Fossati C; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Pigozzi F; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Borrione P; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Pitsiladis Y; School of Sport and Heath Sciences, University of Brighton Welkin House, 30 Carlisle Road, Eastbourne, BN20 7SN, UK. Y.Pitsiladis@brighton.ac.uk.; Centre for Stress and Age-Related Disease, University of Brighton, Brighton, UK. Y.Pitsiladis@brighton.ac.uk.

Publikováno v: BMC medical genomics [BMC Med Genomics] 2023 May 03; Vol. 16 (1), pp. 94. Date of Electronic Publication: 2023 May 03.

Response to the United Nations Human Rights Council's Report on Race and Gender Discrimination in Sport: An Expression of Concern and a Call to Prioritise Research.

Autor: Hamilton BR; Collaborating Centre of Sports Medicine, University of Brighton, Eastbourne, UK.; Centre for Stress and Age-Related Disease, University of Brighton, Eastbourne, UK.; The Gender Identity Clinic Tavistock and Portman NHS Foundation Trust, London, UK., Martinez-Patiño MJ; Faculty of Educational Sciences and Sports, University of Vigo, Galicia, Spain., Barrett J; The Gender Identity Clinic Tavistock and Portman NHS Foundation Trust, London, UK., Seal L; The Gender Identity Clinic Tavistock and Portman NHS Foundation Trust, London, UK., Tucker R; World Rugby, Dublin, Ireland., Papadopoulou T; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; British Association Sport and Exercise Medicine, Doncaster, UK.; Defense Medical Rehabilitation Centre (DMRC), Loughborough, UK., Bigard X; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Union Cycliste Internationale (UCI), Aigle, Switzerland., Kolliari-Turner A; Collaborating Centre of Sports Medicine, University of Brighton, Eastbourne, UK., Löllgen H; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland., Zupet P; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland., Ionescu A; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland., Debruyne A; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland., Jones N; British Association Sport and Exercise Medicine, Doncaster, UK.; British Cycling and University of Liverpool, Liverpool, UK., Steinacker JM; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Division of Sports and Rehabilitation Medicine, Ulm University Hospital, Ulm, Germany., Vonbank K; Department of Pneumology, Pulmonary Function Laboratory, Medicine Clinic (KIMII), University of Vienna, Vienna, Austria., Lima G; Collaborating Centre of Sports Medicine, University of Brighton, Eastbourne, UK.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Fagnani F; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Fossati C; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.; Villa Stuart Sport Clinic, FIFA Medical Center of Excellence, Rome, Italy., Di Luigi L; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Pigozzi F; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy.; Villa Stuart Sport Clinic, FIFA Medical Center of Excellence, Rome, Italy., Casasco M; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Italian Federation of Sports Medicine (FMSI), Rome, Italy., Geistlinger M; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Unit International Law, Department of Constitutional, International and European Law, University of Salzburg, Salzburg, Austria., Wolfarth B; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Department of Sports Medicine, Humboldt University and Charité University School of Medicine, Berlin, Germany., Seto JT; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC, 3052, Australia.; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC, 3052, Australia., Bachl N; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Institute of Sports Science, University of Vienna, Vienna, Austria.; Austrian Institute of Sports Medicine, Vienna, Austria., Twycross-Lewis R; School of Engineering and Materials Science, Queen Mary University of London, London, UK., Niederseer D; Department of Cardiology, University Hospital Zurich University Heart Centre, University of Zurich, Zurich, Switzerland., Bosch A; Division of Exercise Science and Sports Medicine, University of Cape Town, Cape Town, South Africa., Swart J; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Division of Exercise Science and Sports Medicine, University of Cape Town, Cape Town, South Africa., Constantinou D; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Centre for Exercise Science and Sports Medicine, University of the Witwatersrand, Johannesburg, South Africa., Muniz-Pardos B; GENUD Research Group, Faculty of Sport and Health Sciences, Department of Physiatry and Nursing, University of Zaragoza, Zaragoza, Spain., Casajus JA; GENUD Research Group, Faculty of Sport and Health Sciences, Department of Physiatry and Nursing, University of Zaragoza, Zaragoza, Spain., Badtieva V; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russian Federation.; Moscow Research and Practical Centre for Medical Rehabilitation, Restorative and Sports Medicine, Moscow Healthcare Department, Moscow, Russian Federation., Zelenkova I; GENUD Research Group, Faculty of Sport and Health Sciences, Department of Physiatry and Nursing, University of Zaragoza, Zaragoza, Spain.; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia, Moscow, Russian Federation., Bilzon JLJ; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; British Association Sport and Exercise Medicine, Doncaster, UK.; Department for Health, University of Bath, Bath, UK., Dohi M; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Sport Medical Center, Japan Institute of Sports Sciences, Tokyo, Japan., Schneider C; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Orthopaedic Center Theresie, Munich, Germany., Loland S; Institute of Sport and Social Sciences, Norwegian School of Sport Sciences, Oslo, Norway., Verroken M; Sporting Integrity Ltd, Stoke Mandeville, UK.; Centre of Research and Innovation for Sport, Technology and Law (CRISTAL), Faculty of Business and Law, De Montfort University, Leicester, UK., Marqueta PM; Department of Sports Medicine, San Antonio Catholic University of Murcia, Murcia, Spain., Arroyo F; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; FIMS Collaborating Center of Sports Medicine, Guadalajara, Mexico., Pedrinelli A; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Department of Orthopaedics, University of São Paulo Medical School, São Paulo, Brazil., Natsis K; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Intebalkan Medical Centre, FIMS Collaborating Centre of Sports Medicine, Thessaloniki, Greece., Verhagen E; Amsterdam Collaboration On Health and Safety in Sports, Department of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands., Roberts WO; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Department of Family Medicine and Community Health, University of Minnesota, Minneapolis, USA., Lazzoli JK; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Biomedical Institute, Fluminense Federal University Medical School, Niterói, Brazil., Friedman R; Universidade Federal Do Rio Grande Do Sul, Endocrine Unit, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil., Erdogan A; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Gloria Sports Arena, FIMS Collaborating Centre of Sports Medicine, Antalya, Turkey., Cintron AV; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Puerto Rico Sports Medicine Federation, San Juan, Puerto Rico., Yung SP; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Asian Federation of Sports Medicine (AFSM), Hong Kong Center of Sports Medicine and Sports Science, Hong Kong, China., van Rensburg DCJ; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Section Sports Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa., Ramagole DA; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Section Sports Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa., Rozenstoka S; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; FIMS Collaboration Centre of Sports Medicine, Sports Laboratory, Riga, Latvia., Drummond F; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; FIMS Collaboration Centre of Sports Medicine, Instituto de Medicina Do Esporte, Porto Alegre, Brazil., Webborn N; School of Sport and Service Management, University of Brighton, Eastbourne, UK., Guppy FM; Collaborating Centre of Sports Medicine, University of Brighton, Eastbourne, UK.; Centre for Stress and Age-Related Disease, University of Brighton, Eastbourne, UK., Pitsiladis YP; Collaborating Centre of Sports Medicine, University of Brighton, Eastbourne, UK. y.pitsiladis@brighton.ac.uk.; European Federation of Sports Medicine Associations (EFSMA), Lausanne, Switzerland. y.pitsiladis@brighton.ac.uk.; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland. y.pitsiladis@brighton.ac.uk.; Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy. y.pitsiladis@brighton.ac.uk.

Publikováno v: Sports medicine (Auckland, N.Z.) [Sports Med] 2021 Apr; Vol. 51 (4), pp. 839-842. Date of Electronic Publication: 2020 Dec 08.

Cullin-3 dependent deregulation of ACTN1 represents a new pathogenic mechanism in nemaline myopathy.

Autor: Blondelle J; Division of Cardiology, School of Medicine, UCSD, La Jolla, California, USA., Tallapaka K; Division of Cardiology, School of Medicine, UCSD, La Jolla, California, USA., Seto JT; Neuromuscular Research, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia., Ghassemian M; Department of Chemistry and Biochemistry. UCSD, La Jolla, California, USA., Clark M; Division of Cardiology, School of Medicine, UCSD, La Jolla, California, USA., Laitila JM; Folkhälsan Research Center and Medicum, University of Helsinki, Helsinki, Finland., Bournazos A; Kids Neuroscience Centre, Kids Research, Children's Hospital at Westmead, Sydney, New South Wales, Australia.; Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Singer JD; Department of Biology, Portland State University, Portland, Oregon, USA., Lange S; Division of Cardiology, School of Medicine, UCSD, La Jolla, California, USA.; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Publikováno v: JCI insight [JCI Insight] 2019 Apr 16; Vol. 5. Date of Electronic Publication: 2019 Apr 16.

The Effect of ACTN3 Gene Doping on Skeletal Muscle Performance.

Autor: Garton FC; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia., Houweling PJ; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC 3052, Australia., Vukcevic D; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; School of Mathematics and Statistics, Faculty of Science, University of Melbourne, Parkville, VIC 3052, Australia; School of BioSciences, Faculty of Science, University of Melbourne, Parkville, VIC 3052, Australia; Centre for Systems Genomics, University of Melbourne, Parkville, VIC 3052, Australia., Meehan LR; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia., Lee FXZ; Institute for Neuroscience and Muscle Research, The Children's Hospital at Westmead, Sydney, NSW 2145, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW 2145, Australia., Lek M; Institute for Neuroscience and Muscle Research, The Children's Hospital at Westmead, Sydney, NSW 2145, Australia; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA., Roeszler KN; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC 3052, Australia., Hogarth MW; Institute for Neuroscience and Muscle Research, The Children's Hospital at Westmead, Sydney, NSW 2145, Australia., Tiong CF; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia., Zannino D; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC 3052, Australia., Yang N; Institute for Neuroscience and Muscle Research, The Children's Hospital at Westmead, Sydney, NSW 2145, Australia., Leslie S; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; School of Mathematics and Statistics, Faculty of Science, University of Melbourne, Parkville, VIC 3052, Australia; School of BioSciences, Faculty of Science, University of Melbourne, Parkville, VIC 3052, Australia; Centre for Systems Genomics, University of Melbourne, Parkville, VIC 3052, Australia., Gregorevic P; Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia., Head SI; School of Medical Sciences, University of New South Wales, Sydney, NSW 2031, Australia; School of Medicine, Western Sydney University, Sydney, NSW 2751, Australia., Seto JT; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC 3052, Australia., North KN; Murdoch Children's Research Institute, The Royal Children's Hospital, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, The Royal Children's Hospital, Melbourne, VIC 3052, Australia. Electronic address: kathryn.north@mcri.edu.au.

Publikováno v: American journal of human genetics [Am J Hum Genet] 2018 May 03; Vol. 102 (5), pp. 845-857. Date of Electronic Publication: 2018 Apr 26.

Progress and prospects of gene therapy clinical trials for the muscular dystrophies.

Autor: Bengtsson NE; Department of Neurology and., Seto JT; Department of Neurology and., Hall JK; Department of Neurology and., Chamberlain JS; Department of Neurology and Department of Biochemistry, University of Washington School of Medicine, Seattle, WA 98195-7350, USA., Odom GL; Department of Neurology and godom@uw.edu.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2016 Apr 15; Vol. 25 (R1), pp. R9-17. Date of Electronic Publication: 2015 Oct 08.